Mohammad Qrimli1,2, Hamid Ebadi3, Ari Breiner1, Hafsah Siddiqui1, Majed Alabdali1,4, Alon Abraham1, Leif E Lovblom5, Bruce A Perkins5, Vera Bril1. 1. Ellen and Martin Prosserman Centre for Neuromuscular Diseases, Department of Medicine, Toronto General Hospital, University of Toronto University Health Network, 200 Elizabeth Street 5EC-309, Ontario, M5G 2C4, Canada. 2. King Fahad Hospital, Ministry of Health, Madinah, Saudi Arabia. 3. Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada. 4. King Fahad University Hospital, University of Dammam, Dammam, Saudi Arabia. 5. Division of Endocrinology and Metabolism, Department of Medicine, Mount Sinai Hospital and Lunenfeld-Tanenbaum Research Institute, University of Toronto, Toronto, Ontario, Canada.
Abstract
INTRODUCTION: High-resolution ultrasonography (HRU) is a novel method that provides morphological information about peripheral nerves. We aimed to determine reference values for nerve cross-sectional area (CSA) on HRU. METHODS: One hundred healthy volunteers had HRU of median, radial, ulnar, fibular, tibial, sural, and superficial fibular nerves at defined sites. The CSA was measured and the effects of age, gender, and body mass index (BMI) were evaluated. RESULTS: CSA values in healthy subjects are described. CSA is larger in lower limb motor nerves than in sensory nerves at similar sites, and the CSA tends to be symmetrical. The strongest effect on CSA was for age, although gender and BMI had some effects. CONCLUSIONS: This study provides normative values for HRU, and it suggests that further research with age- and gender-specific distributions must be a key priority in the development of HRU for use as a diagnostic test for peripheral nerve diseases.
INTRODUCTION: High-resolution ultrasonography (HRU) is a novel method that provides morphological information about peripheral nerves. We aimed to determine reference values for nerve cross-sectional area (CSA) on HRU. METHODS: One hundred healthy volunteers had HRU of median, radial, ulnar, fibular, tibial, sural, and superficial fibular nerves at defined sites. The CSA was measured and the effects of age, gender, and body mass index (BMI) were evaluated. RESULTS:CSA values in healthy subjects are described. CSA is larger in lower limb motor nerves than in sensory nerves at similar sites, and the CSA tends to be symmetrical. The strongest effect on CSA was for age, although gender and BMI had some effects. CONCLUSIONS: This study provides normative values for HRU, and it suggests that further research with age- and gender-specific distributions must be a key priority in the development of HRU for use as a diagnostic test for peripheral nerve diseases.
Authors: A Picelli; S Tamburin; G Berto; E Chemello; Marialuisa Gandolfi; Leopold Saltuari; Andreas Waldner; Nicola Smania Journal: Funct Neurol Date: 2017 Jul/Sep
Authors: Maria Rasenack; Bernhard F Décard; Sabine Schädelin; Alexander Grimm; Dirk Fischer; Patricia Hafner Journal: BMJ Open Date: 2016-12-09 Impact factor: 2.692