Gongbo Chen1, Xin Sun2, Hongyan Ren3, Xia Wan4, Hecang Huang5, Xiangyun Ma5, Bofu Ning5, Xiaonong Zou6, Weijiang Hu2, Gonghuan Yang7. 1. Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & School of Basic Medicine, Peking Union Medical College, Beijing 100005, China; Cancer Hospital/Institute, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100021, China. 2. National Institute of Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing 100050, China. 3. Institute of Geographic Sciences and Nature Resources Research, Chinese Academy of Sciences, Beijing 100101, China. 4. Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & School of Basic Medicine, Peking Union Medical College, Beijing 100005, China. 5. Xuanwei Center for Disease Control and Prevention, Xuanwei, Qujing, Yunnan 655400, China. 6. Cancer Hospital/Institute, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100021, China. 7. Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & School of Basic Medicine, Peking Union Medical College, Beijing 100005, China. Electronic address: yangghuan@vip.sina.com.
Abstract
OBJECTIVES: To explore the variations in the mortality trends, especially death due to lung cancer, from 1990 to 2013 in Xuanwei City. MATERIALS AND METHODS: Mortality data were collected in Xuanwei during the 2nd and 3rd National Retrospective Sampling Survey on Mortality and Routine Death Registration System (DRS) during 2011-2013. According to the result of the survey on under-reported deaths, mortality data from DRS during 2011-2013 were adjusted. Disease specific mortality rate, age-standardized mortality rate (ASMR) and 45Q15 were calculated in Xuanwei and compared with those in rural areas of China. RESULTS: During three periods, 1990-1992, 2004-2005 and 2011-2013, lung cancer contributed to 56.86%, 58.45% and 63.03% of deaths from all cancers respectively with a much higher proportion than rural areas nationally. The ASMR of lung cancer for males surged from 41.43/10(5) to 88.17/10(5) during 1990-2005 and it surged from 37.70/10(5) to 74.45/10(5) for females. Although they declined slightly during 2011-2013 (82.53/10(5) and 62.62/10(5) for males and females respectively), the ASMR of lung cancer among males in Xuanwei was three times of that in rural areas in China, and it was six times higher among females. The 45Q15 of lung cancer for males in Xuanwei was 3-5 times of that in rural areas of China and for females it was 7-9 times. The high-mortality areas of lung cancer were still located in Laibin, Longchang, Wanshui and Shuanglong Communities. High-mortality areas of lung cancer expanded to their surrounding areas and those in southeast. CONCLUSIONS: Although indoor air pollution caused by smoky coal has been fairly well controlled, patterns of death due to lung cancer have not obviously changed. The mortality rate of lung cancer among females was similar to that among males. Therefore, further studies should be conducted to comprehensively explore the risk factors of lung cancer in Xuanwei.
OBJECTIVES: To explore the variations in the mortality trends, especially death due to lung cancer, from 1990 to 2013 in Xuanwei City. MATERIALS AND METHODS: Mortality data were collected in Xuanwei during the 2nd and 3rd National Retrospective Sampling Survey on Mortality and Routine Death Registration System (DRS) during 2011-2013. According to the result of the survey on under-reported deaths, mortality data from DRS during 2011-2013 were adjusted. Disease specific mortality rate, age-standardized mortality rate (ASMR) and 45Q15 were calculated in Xuanwei and compared with those in rural areas of China. RESULTS: During three periods, 1990-1992, 2004-2005 and 2011-2013, lung cancer contributed to 56.86%, 58.45% and 63.03% of deaths from all cancers respectively with a much higher proportion than rural areas nationally. The ASMR of lung cancer for males surged from 41.43/10(5) to 88.17/10(5) during 1990-2005 and it surged from 37.70/10(5) to 74.45/10(5) for females. Although they declined slightly during 2011-2013 (82.53/10(5) and 62.62/10(5) for males and females respectively), the ASMR of lung cancer among males in Xuanwei was three times of that in rural areas in China, and it was six times higher among females. The 45Q15 of lung cancer for males in Xuanwei was 3-5 times of that in rural areas of China and for females it was 7-9 times. The high-mortality areas of lung cancer were still located in Laibin, Longchang, Wanshui and Shuanglong Communities. High-mortality areas of lung cancer expanded to their surrounding areas and those in southeast. CONCLUSIONS: Although indoor air pollution caused by smoky coal has been fairly well controlled, patterns of death due to lung cancer have not obviously changed. The mortality rate of lung cancer among females was similar to that among males. Therefore, further studies should be conducted to comprehensively explore the risk factors of lung cancer in Xuanwei.
Authors: Hongyan Ren; Wei Cao; Gongbo Chen; Junxing Yang; Liqun Liu; Xia Wan; Gonghuan Yang Journal: Int J Environ Res Public Health Date: 2016-05-06 Impact factor: 3.390