Literature DB >> 26313225

Building a staircase to precision medicine for biliary tract cancer.

Nataliya Razumilava1, Gregory J Gores2.   

Abstract

A new study has conducted a comprehensive exome and transcriptome analysis of a large number of intrahepatic, perihilar and distal cholangiocarcinomas and gallbladder cancers in Japanese patients. This study identifies many new alterations, confirms genetic differences in these distinct subtypes of biliary tract cancer and demonstrates that approximately 40% of described genetic aberrations are potentially targetable.

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Year:  2015        PMID： 26313225     DOI： 10.1038/ng.3386

Source DB:  PubMed          Journal:  Nat Genet        ISSN： 1061-4036            Impact factor:   38.330


  11 in total

1.  Genomic spectra of biliary tract cancer.

Authors:  Hiromi Nakamura; Yasuhito Arai; Yasushi Totoki; Tomoki Shirota; Asmaa Elzawahry; Mamoru Kato; Natsuko Hama; Fumie Hosoda; Tomoko Urushidate; Shoko Ohashi; Nobuyoshi Hiraoka; Hidenori Ojima; Kazuaki Shimada; Takuji Okusaka; Tomoo Kosuge; Shinichi Miyagawa; Tatsuhiro Shibata
Journal:  Nat Genet       Date:  2015-08-10       Impact factor: 38.330

2.  Fibroblast growth factor receptor 2 tyrosine kinase fusions define a unique molecular subtype of cholangiocarcinoma.

Authors:  Yasuhito Arai; Yasushi Totoki; Fumie Hosoda; Tomoki Shirota; Natsuko Hama; Hiromi Nakamura; Hidenori Ojima; Koh Furuta; Kazuaki Shimada; Takuji Okusaka; Tomoo Kosuge; Tatsuhiro Shibata
Journal:  Hepatology       Date:  2014-02-18       Impact factor: 17.425

3.  Integrative molecular analysis of intrahepatic cholangiocarcinoma reveals 2 classes that have different outcomes.

Authors:  Daniela Sia; Yujin Hoshida; Augusto Villanueva; Sasan Roayaie; Joana Ferrer; Barbara Tabak; Judit Peix; Manel Sole; Victoria Tovar; Clara Alsinet; Helena Cornella; Brandy Klotzle; Jian-Bing Fan; Christian Cotsoglou; Swan N Thung; Josep Fuster; Samuel Waxman; Juan Carlos Garcia-Valdecasas; Jordi Bruix; Myron E Schwartz; Rameen Beroukhim; Vincenzo Mazzaferro; Josep M Llovet
Journal:  Gastroenterology       Date:  2013-01-04       Impact factor: 22.682

Review 4.  Cholangiocarcinoma.

Authors:  Nataliya Razumilava; Gregory J Gores
Journal:  Lancet       Date:  2014-02-26       Impact factor: 79.321

5.  Detection of a recurrent DNAJB1-PRKACA chimeric transcript in fibrolamellar hepatocellular carcinoma.

Authors:  Joshua N Honeyman; Elana P Simon; Nicolas Robine; Rachel Chiaroni-Clarke; David G Darcy; Irene Isabel P Lim; Caroline E Gleason; Jennifer M Murphy; Brad R Rosenberg; Lydia Teegan; Constantin N Takacs; Sergio Botero; Rachel Belote; Soren Germer; Anne-Katrin Emde; Vladimir Vacic; Umesh Bhanot; Michael P LaQuaglia; Sanford M Simon
Journal:  Science       Date:  2014-02-28       Impact factor: 47.728

6.  Pattern of chromosomal aberrations in primary liver cancers identified by comparative genomic hybridization.

Authors:  Kia Homayounfar; Bastian Gunawan; Silke Cameron; Florian Haller; Daniel Baumhoer; Stefan Uecker; Bjoern Sander; Giuliano Ramadori; Thomas Lorf; László Füzesi
Journal:  Hum Pathol       Date:  2009-02-05       Impact factor: 3.466

7.  High frequency of telomerase reverse-transcriptase promoter somatic mutations in hepatocellular carcinoma and preneoplastic lesions.

Authors:  Jean Charles Nault; Maxime Mallet; Camilla Pilati; Julien Calderaro; Paulette Bioulac-Sage; Christophe Laurent; Alexis Laurent; Daniel Cherqui; Charles Balabaud; Jessica Zucman-Rossi; Jessica Zucman Rossi
Journal:  Nat Commun       Date:  2013       Impact factor: 14.919

8.  Mutation profiling in cholangiocarcinoma: prognostic and therapeutic implications.

Authors:  Chaitanya R Churi; Rachna Shroff; Ying Wang; Asif Rashid; HyunSeon C Kang; Jacqueline Weatherly; Mingxin Zuo; Ralph Zinner; David Hong; Funda Meric-Bernstam; Filip Janku; Christopher H Crane; Lopa Mishra; Jean-Nicholas Vauthey; Robert A Wolff; Gordon Mills; Milind Javle
Journal:  PLoS One       Date:  2014-12-23       Impact factor: 3.240

9.  Integrated genomic characterization reveals novel, therapeutically relevant drug targets in FGFR and EGFR pathways in sporadic intrahepatic cholangiocarcinoma.

Authors:  Mitesh J Borad; Mia D Champion; Jan B Egan; Winnie S Liang; Rafael Fonseca; Alan H Bryce; Ann E McCullough; Michael T Barrett; Katherine Hunt; Maitray D Patel; Scott W Young; Joseph M Collins; Alvin C Silva; Rachel M Condjella; Matthew Block; Robert R McWilliams; Konstantinos N Lazaridis; Eric W Klee; Keith C Bible; Pamela Harris; Gavin R Oliver; Jaysheel D Bhavsar; Asha A Nair; Sumit Middha; Yan Asmann; Jean-Pierre Kocher; Kimberly Schahl; Benjamin R Kipp; Emily G Barr Fritcher; Angela Baker; Jessica Aldrich; Ahmet Kurdoglu; Tyler Izatt; Alexis Christoforides; Irene Cherni; Sara Nasser; Rebecca Reiman; Lori Phillips; Jackie McDonald; Jonathan Adkins; Stephen D Mastrian; Pamela Placek; Aprill T Watanabe; Janine Lobello; Haiyong Han; Daniel Von Hoff; David W Craig; A Keith Stewart; John D Carpten
Journal:  PLoS Genet       Date:  2014-02-13       Impact factor: 5.917

10.  Identification of targetable FGFR gene fusions in diverse cancers.

Authors:  Yi-Mi Wu; Fengyun Su; Shanker Kalyana-Sundaram; Nickolay Khazanov; Bushra Ateeq; Xuhong Cao; Robert J Lonigro; Pankaj Vats; Rui Wang; Su-Fang Lin; Ann-Joy Cheng; Lakshmi P Kunju; Javed Siddiqui; Scott A Tomlins; Peter Wyngaard; Seth Sadis; Sameek Roychowdhury; Maha H Hussain; Felix Y Feng; Mark M Zalupski; Moshe Talpaz; Kenneth J Pienta; Daniel R Rhodes; Dan R Robinson; Arul M Chinnaiyan
Journal:  Cancer Discov       Date:  2013-04-04       Impact factor: 39.397
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  4 in total

1.  Evaluation of NUC-1031: a first-in-class ProTide in biliary tract cancer.

Authors:  Mansi Arora; James M Bogenberger; Amro Abdelrahman; Jennifer L Leiting; Xianfeng Chen; Jan B Egan; Aradhana Kasimsetty; Elzbieta Lenkiewicz; Smriti Malasi; Pedro Luiz Serrano Uson; Bolni Marius Nagalo; Yumei Zhou; Marcela A Salomao; Heidi E Kosiorek; Esteban Braggio; Michael T Barrett; Mark J Truty; Mitesh J Borad
Journal:  Cancer Chemother Pharmacol       Date:  2020-05-21       Impact factor: 3.288

2.  Variants in oxidative stress-related genes affect the chemosensitivity through Nrf2-mediated signaling pathway in biliary tract cancer.

Authors:  Ming Zhan; Hui Wang; Sun-Wang Xu; Lin-Hua Yang; Wei Chen; Shuang-Xia Zhao; Hui Shen; Qiang Liu; Rui-Meng Yang; Jian Wang
Journal:  EBioMedicine       Date:  2019-10-04       Impact factor: 8.143

Review 3.  Emerging role of precision medicine in biliary tract cancers.

Authors:  James M Bogenberger; Thomas T DeLeon; Mansi Arora; Daniel H Ahn; Mitesh J Borad
Journal:  NPJ Precis Oncol       Date:  2018-10-03

4.  Guided chemotherapy based on patient-derived mini-xenograft models improves survival of gallbladder carcinoma patients.

Authors:  Ming Zhan; Rui-Meng Yang; Hui Wang; Min He; Wei Chen; Sun-Wang Xu; Lin-Hua Yang; Qiang Liu; Man-Mei Long; Jian Wang
Journal:  Cancer Commun (Lond)       Date:  2018-07-17
  4 in total

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