| Literature DB >> 26308768 |
Larissa Gabriela Faqueti1, Ingrid Vicente Farias1, Elem Cristina Sabedot1, Franco Delle Monache1, Arturo San Feliciano2, Ivânia Teresinha Albrecht Schuquel3, Valdir Cechinel-Filho1, Alexandre Bella Cruz1, Christiane Meyre-Silva1.
Abstract
Certain members of the genus Eugenia are used as foods. One of these species is Eugenia umbelliflora, which is used for its fruits. The aim of the study was to isolate the constituents of the CH2Cl2 fraction obtained from E. umbelliflora O. Berg (Myrtaceae) and also to evaluate its antimicrobial properties. Two new meroterpenoids, eugenial C (3) and eugenial D (4) were isolated from the unripe fruits of E. umbelliflora and their structures established mainly by extensive NMR spectroscopy. In previous studies, the CH2Cl2 extract showed significant antibacterial activity, which can be attributed to meroterpenoids isolated in this study. The compounds eugenials C and D exhibited potent activity against Bacillus subtilis and Staphylococcus aureus and different strains of MRSA and activity similar to those of the antibiotics used in antimicrobial therapies.Entities:
Keywords: Eugenia umbelliflora; Myrtaceae; antibacterial activity; eugenial C; eugenial D; phloroglucinol-sesquiterpene
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Year: 2015 PMID： 26308768 DOI： 10.1021/acs.jafc.5b03562
Source DB: PubMed Journal: J Agric Food Chem ISSN： 0021-8561 Impact factor: 5.279