Literature DB >> 26307435

Dose-response association of moderate-to-vigorous physical activity with cardiovascular biomarkers and all-cause mortality: Considerations by individual sports, exercise and recreational physical activities.

Paul D Loprinzi1.   

Abstract

BACKGROUND: Previous research demonstrates that moderate-to-vigorous physical activity (MVPA) is associated with reduced all-cause mortality risk. Our understanding of whether individual physical activities are associated with all-cause mortality is less understood.
METHODS: Data from the 1999-2006 NHANES were employed, with follow-up through 2011. 48 different individual physical activities (e.g., swimming, running, bicycling) were assessed, and total MVPA MET-min-month was calculated based on their responses to these 48 individual physical activities.
RESULTS: Greater engagement in MVPA was associated with more favorable cardiovascular biomarkers, particularly for men. Even after adjustment for total MVPA, different individual physical activities were associated with cardiovascular biomarkers across gender. When compared to those not meeting guidelines (0-1999 MVPA MET-min-month), a dose-response association between MVPA and mortality was observed, with those engaging in 5 times the guideline level having the lowest risk of all-cause mortality (45% reduced risk). There was no evidence of a harmful effect of very high MVPA (e.g., 20,000+ MVPA MET-min-month).
CONCLUSIONS: Engaging in MVPA even below the minimum recommendation was associated with survival benefits, and the greatest survival effects occurred at a dose of approximately 5 times the minimum recommendation. Although very high levels (e.g., 10 times the minimum recommendation) of self-reported MVPA did not demonstrate the greatest survival effects, high levels of physical activity did not appear to have harmful effects.
Copyright © 2015 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Cardiovascular biomarkers; Epidemiology; Mortality; Survival

Mesh:

Substances:

Year:  2015        PMID: 26307435     DOI: 10.1016/j.ypmed.2015.08.014

Source DB:  PubMed          Journal:  Prev Med        ISSN: 0091-7435            Impact factor:   4.018


  20 in total

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Journal:  Age (Dordr)       Date:  2016-01-14

2.  The protective effects of a novel fitness-fatness index on all-cause mortality among adults with cardiovascular disease.

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Journal:  Clin Cardiol       Date:  2017-03-10       Impact factor: 2.882

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Authors:  Paul D Loprinzi; Meghan K Edwards; Ovuokerie Addoh; John P Bentley
Journal:  Eur J Appl Physiol       Date:  2018-01-19       Impact factor: 3.078

4.  The Association Between Weight Status, Weight History, Physical Activity, and Cognitive Task Performance.

Authors:  Meghan K Edwards; Scott J Dankel; Jeremy P Loenneke; Paul D Loprinzi
Journal:  Int J Behav Med       Date:  2017-06

5.  Lower extremity muscular strength, sedentary behavior, and mortality.

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Journal:  Age (Dordr)       Date:  2016-03-01

6.  Sleep, Sedentary Behavior, Physical Activity, and Cardiovascular Health: MESA.

Authors:  Charles German; Nour Makarem; Jason Fanning; Susan Redline; Tali Elfassy; Amanda McClain; Marwah Abdalla; Brooke Aggarwal; Norrina Allen; Mercedes Carnethon
Journal:  Med Sci Sports Exerc       Date:  2021-04-01

7.  Survival effects of physical activity on mortality among persons with liver disease.

Authors:  Paul D Loprinzi; Lisa B VanWagner
Journal:  Prev Med Rep       Date:  2015-12-29

8.  Psycho-socioeconomic bio-behavioral associations on all-cause mortality: cohort study.

Authors:  Paul D Loprinzi; Robert E Davis
Journal:  Health Promot Perspect       Date:  2016-06-11

9.  The association of physical activity and cholesterol concentrations across different combinations of central adiposity and body mass index.

Authors:  Paul D Loprinzi; Ovuokerie Addoh
Journal:  Health Promot Perspect       Date:  2016-08-10

10.  Effect of physical activity on mortality risk among Americans with retinopathy.

Authors:  Paul D Loprinzi
Journal:  Health Promot Perspect       Date:  2016-08-10
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