Literature DB >> 26299275

Update on TBI and Cognitive Impairment in Military Veterans.

Gregory A Elder1.   

Abstract

Traumatic brain injury (TBI) is a common cause of morbidity and mortality in military life. Interest in military TBI has increased recently due to the conflicts in Iraq and Afghanistan. Certain types of TBI are relatively unique to the military, the most prominent being blast-related TBI. Blast-related mild TBI has been of particular concern in veterans from the most recent conflicts although controversy remains concerning its separation from post-traumatic stress disorder. TBI is also a risk factor for the later development of neurodegenerative diseases in which cognitive impairment is prominent putting veterans at risk for disorders including Alzheimer's disease and chronic traumatic encephalopathy. Recent evidence associating TBI with chronic cognitive impairment is reviewed in the context of its relevance to military veterans.

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Year:  2015        PMID: 26299275     DOI: 10.1007/s11910-015-0591-8

Source DB:  PubMed          Journal:  Curr Neurol Neurosci Rep        ISSN: 1528-4042            Impact factor:   5.081


  75 in total

1.  Chronic traumatic encephalopathy in blast-exposed military veterans and a blast neurotrauma mouse model.

Authors:  Lee E Goldstein; Andrew M Fisher; Chad A Tagge; Xiao-Lei Zhang; Libor Velisek; John A Sullivan; Chirag Upreti; Jonathan M Kracht; Maria Ericsson; Mark W Wojnarowicz; Cezar J Goletiani; Giorgi M Maglakelidze; Noel Casey; Juliet A Moncaster; Olga Minaeva; Robert D Moir; Christopher J Nowinski; Robert A Stern; Robert C Cantu; James Geiling; Jan K Blusztajn; Benjamin L Wolozin; Tsuneya Ikezu; Thor D Stein; Andrew E Budson; Neil W Kowall; David Chargin; Andre Sharon; Sudad Saman; Garth F Hall; William C Moss; Robin O Cleveland; Rudolph E Tanzi; Patric K Stanton; Ann C McKee
Journal:  Sci Transl Med       Date:  2012-05-16       Impact factor: 17.956

Review 2.  Cognitive changes and dementia risk after traumatic brain injury: implications for aging military personnel.

Authors:  Andrea S Vincent; Tresa M Roebuck-Spencer; Alison Cernich
Journal:  Alzheimers Dement       Date:  2014-06       Impact factor: 21.566

Review 3.  Military risk factors for cognitive decline, dementia and Alzheimer's disease.

Authors:  Dallas P Veitch; Karl E Friedl; Michael W Weiner
Journal:  Curr Alzheimer Res       Date:  2013-11       Impact factor: 3.498

4.  Blast exposure induces post-traumatic stress disorder-related traits in a rat model of mild traumatic brain injury.

Authors:  Gregory A Elder; Nathan P Dorr; Rita De Gasperi; Miguel A Gama Sosa; Michael C Shaughness; Eric Maudlin-Jeronimo; Aaron A Hall; Richard M McCarron; Stephen T Ahlers
Journal:  J Neurotrauma       Date:  2012-08-27       Impact factor: 5.269

Review 5.  Head trauma preceding PD: a case-control study.

Authors:  J H Bower; D M Maraganore; B J Peterson; S K McDonnell; J E Ahlskog; W A Rocca
Journal:  Neurology       Date:  2003-05-27       Impact factor: 9.910

6.  Prevalence and screening of traumatic brain injury among veterans seeking mental health services.

Authors:  Lisa A Brenner; Beeta Y Homaifar; Jennifer H Olson-Madden; Herbert T Nagamoto; Joe Huggins; Alexandra L Schneider; Jeri E Forster; Bridget Matarazzo; John D Corrigan
Journal:  J Head Trauma Rehabil       Date:  2013 Jan-Feb       Impact factor: 2.710

7.  Head injury as a risk factor for Alzheimer's disease: the evidence 10 years on; a partial replication.

Authors:  S Fleminger; D L Oliver; S Lovestone; S Rabe-Hesketh; A Giora
Journal:  J Neurol Neurosurg Psychiatry       Date:  2003-07       Impact factor: 10.154

Review 8.  Mild traumatic brain injury and posttraumatic stress disorder in returning veterans: perspectives from cognitive neuroscience.

Authors:  Jennifer J Vasterling; Mieke Verfaellie; Karen D Sullivan
Journal:  Clin Psychol Rev       Date:  2009-08-21

9.  A case-control study examining whether neurological deficits and PTSD in combat veterans are related to episodes of mild TBI.

Authors:  Robert Louis Ruff; Ronald George Riechers; Xiao-Feng Wang; Traci Piero; Suzanne Smith Ruff
Journal:  BMJ Open       Date:  2012-03-18       Impact factor: 2.692

Review 10.  Effects of low-level blast exposure on the nervous system: is there really a controversy?

Authors:  Gregory A Elder; James R Stone; Stephen T Ahlers
Journal:  Front Neurol       Date:  2014-12-19       Impact factor: 4.003

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  17 in total

1.  Exposure to a Predator Scent Induces Chronic Behavioral Changes in Rats Previously Exposed to Low-level Blast: Implications for the Relationship of Blast-Related TBI to PTSD.

Authors:  Georgina Perez-Garcia; Miguel A Gama Sosa; Rita De Gasperi; Margaret Lashof-Sullivan; Eric Maudlin-Jeronimo; James R Stone; Fatemeh Haghighi; Stephen T Ahlers; Gregory A Elder
Journal:  Front Neurol       Date:  2016-10-18       Impact factor: 4.003

Review 2.  Selective Serotonin Reuptake Inhibitors for Treating Neurocognitive and Neuropsychiatric Disorders Following Traumatic Brain Injury: An Evaluation of Current Evidence.

Authors:  John K Yue; John F Burke; Pavan S Upadhyayula; Ethan A Winkler; Hansen Deng; Caitlin K Robinson; Romain Pirracchio; Catherine G Suen; Sourabh Sharma; Adam R Ferguson; Laura B Ngwenya; Murray B Stein; Geoffrey T Manley; Phiroz E Tarapore
Journal:  Brain Sci       Date:  2017-07-25

Review 3.  Mast Cell Activation in Brain Injury, Stress, and Post-traumatic Stress Disorder and Alzheimer's Disease Pathogenesis.

Authors:  Duraisamy Kempuraj; Govindhasamy P Selvakumar; Ramasamy Thangavel; Mohammad E Ahmed; Smita Zaheer; Sudhanshu P Raikwar; Shankar S Iyer; Sachin M Bhagavan; Swathi Beladakere-Ramaswamy; Asgar Zaheer
Journal:  Front Neurosci       Date:  2017-12-12       Impact factor: 4.677

Review 4.  Neuroprotective and neuroregenerative potential of pharmacologically-induced hypothermia with D-alanine D-leucine enkephalin in brain injury.

Authors:  M Grant Liska; Marci G Crowley; Julian P Tuazon; Cesar V Borlongan
Journal:  Neural Regen Res       Date:  2018-12       Impact factor: 5.135

5.  Low-level blast exposure disrupts gliovascular and neurovascular connections and induces a chronic vascular pathology in rat brain.

Authors:  Miguel A Gama Sosa; Rita De Gasperi; Georgina S Perez Garcia; Gissel M Perez; Courtney Searcy; Danielle Vargas; Alicia Spencer; Pierce L Janssen; Anna E Tschiffely; Richard M McCarron; Benjamin Ache; Rajaram Manoharan; William G Janssen; Susan J Tappan; Russell W Hanson; Sam Gandy; Patrick R Hof; Stephen T Ahlers; Gregory A Elder
Journal:  Acta Neuropathol Commun       Date:  2019-01-09       Impact factor: 7.801

6.  Orientation of neurites influences severity of mechanically induced tau pathology.

Authors:  Nicholas J Braun; Dezhi Liao; Patrick W Alford
Journal:  Biophys J       Date:  2021-07-20       Impact factor: 3.699

7.  Progressive Cognitive and Post-Traumatic Stress Disorder-Related Behavioral Traits in Rats Exposed to Repetitive Low-Level Blast.

Authors:  Georgina Perez Garcia; Gissel M Perez; Rita De Gasperi; Miguel A Gama Sosa; Alena Otero-Pagan; Dylan Pryor; Rania Abutarboush; Usmah Kawoos; Patrick R Hof; David G Cook; Sam Gandy; Stephen T Ahlers; Gregory A Elder
Journal:  J Neurotrauma       Date:  2021-01-25       Impact factor: 4.869

8.  PTSD-Related Behavioral Traits in a Rat Model of Blast-Induced mTBI Are Reversed by the mGluR2/3 Receptor Antagonist BCI-838.

Authors:  Georgina Perez-Garcia; Rita De Gasperi; Miguel A Gama Sosa; Gissel M Perez; Alena Otero-Pagan; Anna Tschiffely; Richard M McCarron; Stephen T Ahlers; Gregory A Elder; Sam Gandy
Journal:  eNeuro       Date:  2018-01-30

9.  Hemostatic nanoparticles increase survival, mitigate neuropathology and alleviate anxiety in a rodent blast trauma model.

Authors:  W Brad Hubbard; Margaret Lashof-Sullivan; Shaylen Greenberg; Carly Norris; Joseph Eck; Erin Lavik; Pamela VandeVord
Journal:  Sci Rep       Date:  2018-07-13       Impact factor: 4.379

10.  Brain and blood biomarkers of tauopathy and neuronal injury in humans and rats with neurobehavioral syndromes following blast exposure.

Authors:  Dara L Dickstein; Rita De Gasperi; Miguel A Gama Sosa; Georgina Perez-Garcia; Jennifer A Short; Heidi Sosa; Gissel M Perez; Anna E Tschiffely; Kristen Dams-O'Connor; Mariel Y Pullman; Karin Knesaurek; Andrew Knutsen; Dzung L Pham; Lale Soleimani; Barry D Jordan; Wayne A Gordon; Bradley N Delman; Gleb Shumyatsky; Pashtun-Poh Shahim; Steven T DeKosky; James R Stone; Elaine Peskind; Kaj Blennow; Henrik Zetterberg; Steven A Chance; Mario Torso; Lale Kostakoglu; Mary Sano; Patrick R Hof; Stephen T Ahlers; Sam Gandy; Gregory A Elder
Journal:  Mol Psychiatry       Date:  2020-02-25       Impact factor: 15.992

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