Leticia Ferreira1, Bruno Jham2, Rouba Assi3, Allison Readinger4, Harvey P Kessler5. 1. Department of Biomedical Sciences, Texas A&M University Baylor College of Dentistry, Dallas, Texas, USA; Assistant Professor, Department of Dental Practice, University of the Pacific Arthur A. Dugoni School of Dentistry, San Francisco, California, USA. Electronic address: Lferreira@pacific.edu. 2. Department of Oncology and Diagnostic Sciences, School of Dentistry, University of Maryland, Baltimore, Maryland, USA; Assistant Professor, College of Dental Medicine Illinois, Midwestern University, Downers Grove, Illinois, USA. 3. Department of Biomedical Sciences, Texas A&M University Baylor College of Dentistry, Dallas, Texas, USA. 4. Pathologists' Biomedical Laboratories, LLP, Baylor University Medical Center, Dallas, Texas, USA. 5. Department of Diagnostic Sciences, Texas A&M University Baylor College of Dentistry, Dallas, Texas, USA.
Abstract
OBJECTIVE: The purpose of this study was to evaluate the clinical and histopathologic features of oral melanocytic nevi (OMN). STUDY DESIGN: One hundred cases of OMN were retrieved from the files of two oral pathology services, and the data were analyzed with regard to histologic type and clinical features. RESULTS: Intramucosal nevus was the most common type (61%), followed by common blue nevus (23%), compound nevus (7%), and junctional nevus (3%). Combined nevus and cellular blue nevus were rare (2% each). The hard palate was the most commonly affected site (33%), followed by the buccal mucosa (18%), vermilion border of the lip (18%), and gingiva (15%). An interesting case of intramucosal nevus with lipomatosus-like changes and neurotization and two cases of oral dysplastic nevus are also reported. CONCLUSIONS: Intramucosal and common blue nevi are the most common types of OMN. Dysplastic nevus, which is recognized as a marker for melanoma in the skin, can rarely involve the oral cavity. Accordingly, dentists, especially oral and maxillofacial pathologists, should become familiar with the clinical and histopathologic features of this entity.
OBJECTIVE: The purpose of this study was to evaluate the clinical and histopathologic features of oral melanocytic nevi (OMN). STUDY DESIGN: One hundred cases of OMN were retrieved from the files of two oral pathology services, and the data were analyzed with regard to histologic type and clinical features. RESULTS: Intramucosal nevus was the most common type (61%), followed by common blue nevus (23%), compound nevus (7%), and junctional nevus (3%). Combined nevus and cellular blue nevus were rare (2% each). The hard palate was the most commonly affected site (33%), followed by the buccal mucosa (18%), vermilion border of the lip (18%), and gingiva (15%). An interesting case of intramucosal nevus with lipomatosus-like changes and neurotization and two cases of oral dysplastic nevus are also reported. CONCLUSIONS: Intramucosal and common blue nevi are the most common types of OMN. Dysplastic nevus, which is recognized as a marker for melanoma in the skin, can rarely involve the oral cavity. Accordingly, dentists, especially oral and maxillofacial pathologists, should become familiar with the clinical and histopathologic features of this entity.
Authors: Johannes Laimer; Raphael Henn; Tom Helten; Susanne Sprung; Bettina Zelger; Bernhard Zelger; René Steiner; Dagmar Schnabl; Vincent Offermanns; Emanuel Bruckmoser; Christian W Huck Journal: PLoS One Date: 2018-11-06 Impact factor: 3.240
Authors: Ana Teresa Tavares; André Pereira; João Pimentel; Marcelo Prates; Luís Fonseca; Maria Rosário Marques; Francisco Proença Journal: Case Rep Dermatol Med Date: 2022-02-15