Literature DB >> 26294731

Abnormal Hedgehog pathway in myelodysplastic syndrome and its impact on patients' outcome.

Juliana M Xavier-Ferrucio1, Fernando Vieira Pericole1, Matheus Rodrigues Lopes1, Paulo Latuf-Filho2, Karin Spät Albino Barcellos1, Amanda Inácio Dias1, Paula de Melo Campos1, Fabiola Traina1, Jose Vassallo2, Sara Teresinha Olalla Saad1, Patricia Favaro3.   

Abstract

Entities:  

Keywords:  Hedgehog pathway; SMO expression; myelodysplastic syndrome

Mesh：

Substances：

Year:  2015        PMID： 26294731      PMCID： PMC4666338          DOI： 10.3324/haematol.2015.124040

Source DB:  PubMed          Journal:  Haematologica        ISSN： 0390-6078            Impact factor:   9.941


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  16 in total

1.  Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method.

Authors:  K J Livak; T D Schmittgen
Journal:  Methods       Date:  2001-12       Impact factor: 3.608

Review 2.  Update on developments in the diagnosis and prognostic evaluation of patients with myelodysplastic syndromes (MDS): consensus statements and report from an expert workshop.

Authors:  Uwe Platzbecker; Valeria Santini; Ghulam J Mufti; Claudia Haferlach; Jaroslaw P Maciejewski; Sophie Park; Francesc Solé; Arjan A van de Loosdrecht; Detlef Haase
Journal:  Leuk Res       Date:  2011-12-03       Impact factor: 3.156

3.  Expression of smoothened protein in colon cancer and its prognostic value for postoperative liver metastasis.

Authors:  Yin-Lu Ding; Qi-San Wang; Wei-Min Zhao; Lei Xiang
Journal:  Asian Pac J Cancer Prev       Date:  2012

Review 4.  Hedgehog beyond medulloblastoma and basal cell carcinoma.

Authors:  Stephan Teglund; Rune Toftgård
Journal:  Biochim Biophys Acta       Date:  2010-01-18

5.  Expression of Sonic hedgehog pathway genes is altered in colonic neoplasia.

Authors:  Anca Oniscu; Roberta M James; Robert G Morris; Scott Bader; Roger D G Malcomson; David J Harrison
Journal:  J Pathol       Date:  2004-08       Impact factor: 7.996

6.  Reduced level of smoothened suppresses intestinal tumorigenesis by down-regulation of Wnt signaling.

Authors:  Sumimasa Arimura; Akihiro Matsunaga; Takanori Kitamura; Koji Aoki; Masahiro Aoki; Makoto M Taketo
Journal:  Gastroenterology       Date:  2009-05-07       Impact factor: 22.682

7.  Drug resistance is dramatically restored by hedgehog inhibitors in CD34+ leukemic cells.

Authors:  Masayoshi Kobune; Rishu Takimoto; Kazuyuki Murase; Satoshi Iyama; Tsutomu Sato; Shohei Kikuchi; Yutaka Kawano; Kohji Miyanishi; Yasushi Sato; Yoshiro Niitsu; Junji Kato
Journal:  Cancer Sci       Date:  2009-02-24       Impact factor: 6.716

8.  Prognostic value of hedgehog signal component expressions in hepatoblastoma patients.

Authors:  Ying-Cun Li; Yu-Hua Deng; Zhen-Hua Guo; Ming-Man Zhang; Jin Zhu; Chon-Lun Pu; Chun-Ping Xiang; Chun-Bao Guo
Journal:  Eur J Med Res       Date:  2010-11-25       Impact factor: 2.175

9.  Stromal cells expressing hedgehog-interacting protein regulate the proliferation of myeloid neoplasms.

Authors:  M Kobune; S Iyama; S Kikuchi; H Horiguchi; T Sato; K Murase; Y Kawano; K Takada; K Ono; Y Kamihara; T Hayashi; K Miyanishi; Y Sato; R Takimoto; J Kato
Journal:  Blood Cancer J       Date:  2012-09-07       Impact factor: 11.037

10.  SMO expression level correlates with overall survival in patients with malignant pleural mesothelioma.

Authors:  Yi Zhang; Jianxing He; Fang Zhang; Hui Li; Dongsheng Yue; Changli Wang; David M Jablons; Biao He; Natalie Lui
Journal:  J Exp Clin Cancer Res       Date:  2013-02-05
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  5 in total

1.  BNIP3L in myelodysplastic syndromes and acute myeloid leukemia: impact on disease outcome and cellular response to decitabine.

Authors:  Mariana Lazarini; João Agostinho Machado-Neto; Adriana da Silva Santos Duarte; Fernando Vieira Pericole; Karla Priscila Vieira; Fernanda S Niemann; Marisa Alvarez; Fabiola Traina; Sara Teresinha Olalla Saad
Journal:  Haematologica       Date:  2016-07-21       Impact factor: 9.941

Review 2.  Targeting multiple signaling pathways: the new approach to acute myeloid leukemia therapy.

Authors:  Jenna L Carter; Katie Hege; Jay Yang; Hasini A Kalpage; Yongwei Su; Holly Edwards; Maik Hüttemann; Jeffrey W Taub; Yubin Ge
Journal:  Signal Transduct Target Ther       Date:  2020-12-18

3.  Hedgehog/GLI1 activation leads to leukemic transformation of myelodysplastic syndrome in vivo and GLI1 inhibition results in antitumor activity.

Authors:  Bonnie W Lau; Kyounghee Huh; Rafael Madero-Marroquin; Federico De Marchi; Yiting Lim; Qiuju Wang; Francisco Lobo; Luigi Marchionni; Douglas B Smith; Amy DeZern; Mark J Levis; Peter D Aplan; William Matsui; Lukasz P Gondek
Journal:  Oncogene       Date:  2018-08-31       Impact factor: 9.867

Review 4.  Targeting Hedgehog (Hh) Pathway for the Acute Myeloid Leukemia Treatment.

Authors:  Toshiki Terao; Yosuke Minami
Journal:  Cells       Date:  2019-04-03       Impact factor: 6.600

5.  Hematopoietic defects in response to reduced Arhgap21.

Authors:  Juliana Xavier-Ferrucio; Lauremília Ricon; Karla Vieira; Ana Leda Longhini; Mariana Lazarini; Carolina Louzão Bigarella; Gilberto Franchi; Diane S Krause; Sara T O Saad
Journal:  Stem Cell Res       Date:  2017-11-23       Impact factor: 2.020
  5 in total

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