Literature DB >> 26294706

Longitudinal Course of Clients With Co-occurring Schizophrenia-Spectrum and Substance Use Disorders in Urban Mental Health Centers: A 7-Year Prospective Study.

Robert E Drake1, Alison E Luciano2, Kim T Mueser3, Nancy H Covell4, Susan M Essock4, Haiyi Xie2, Gregory J McHugo5.   

Abstract

OBJECTIVE: A previous longitudinal study in rural New Hampshire showed that community mental health center clients with co-occurring schizophrenia-spectrum and substance use disorders (SZ/SUD) improved steadily and substantially over 10 years. The current study examined 7 years of prospective clinical and functional outcomes among inner-city Connecticut (CT) community mental health center clients with SZ/SUD.
METHOD: Participants were 150 adults with SZ/SUD, selected for high service needs, in 2 inner-city mental health centers in CT. Initially, all received integrated mental health and substance abuse treatments for at least the first 3 years as part of a clinical trial. Assessments at baseline and yearly over 7 years measured progress toward 6 target clinical and functional outcomes: absence of psychiatric symptoms, remission of substance abuse, independent housing, competitive employment, social contact with non-users of substances, and life satisfaction.
RESULTS: The CT SZ/SUD participants improved significantly on 5 of the 6 main outcomes: absence of psychiatric symptoms (45%-70%), remission of substance use disorders (8%-61%), independent housing (33%-47%), competitive employment (14%-28%), and life satisfaction (35%-53%). Only social contact with nonusers of substances was unimproved (14%-17%).
CONCLUSIONS: Many urban community mental health center clients with SZ/SUD and access to integrated treatment improve significantly on clinical, vocational, residential, and life satisfaction outcomes over time, similar to clients with SZ/SUD in rural areas. Thus, the long-term course for people with SZ/SUD is variable but often quite positive.
© The Author 2015. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. All rights reserved. For permissions, please email: journals.permissions@oup.com.

Entities:  

Keywords:  co-occurring substance disorders; long-term course; schizophrenia

Mesh:

Year:  2015        PMID: 26294706      PMCID: PMC4681561          DOI: 10.1093/schbul/sbv110

Source DB:  PubMed          Journal:  Schizophr Bull        ISSN: 0586-7614            Impact factor:   9.306


  29 in total

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Authors:  M P Salyers; K T Mueser
Journal:  Schizophr Res       Date:  2001-03-01       Impact factor: 4.939

2.  The Structured Clinical Interview for DSM-III-R (SCID). I: History, rationale, and description.

Authors:  R L Spitzer; J B Williams; M Gibbon; M B First
Journal:  Arch Gen Psychiatry       Date:  1992-08

3.  National Institute of Mental Health longitudinal study of chronic schizophrenia. Prognosis and predictors of outcome.

Authors:  A Breier; J L Schreiber; J Dyer; D Pickar
Journal:  Arch Gen Psychiatry       Date:  1991-03

4.  Treatment of alcoholism among schizophrenic outpatients: 4-year outcomes.

Authors:  R E Drake; G J McHugo; D L Noordsy
Journal:  Am J Psychiatry       Date:  1993-02       Impact factor: 18.112

5.  The Vermont longitudinal study of persons with severe mental illness, II: Long-term outcome of subjects who retrospectively met DSM-III criteria for schizophrenia.

Authors:  C M Harding; G W Brooks; T Ashikaga; J S Strauss; A Breier
Journal:  Am J Psychiatry       Date:  1987-06       Impact factor: 18.112

6.  Prevalence of substance abuse in schizophrenia: demographic and clinical correlates.

Authors:  K T Mueser; P R Yarnold; D F Levinson; H Singh; A S Bellack; K Kee; R L Morrison; K G Yadalam
Journal:  Schizophr Bull       Date:  1990       Impact factor: 9.306

7.  Diagnosis of alcohol use disorders in schizophrenia.

Authors:  R E Drake; F C Osher; D L Noordsy; S C Hurlbut; G B Teague; M S Beaudett
Journal:  Schizophr Bull       Date:  1990       Impact factor: 9.306

8.  Symptom monitoring in the rehabilitation of schizophrenic patients.

Authors:  D Lukoff; R P Liberman; K H Nuechterlein
Journal:  Schizophr Bull       Date:  1986       Impact factor: 9.306

9.  An improved diagnostic evaluation instrument for substance abuse patients. The Addiction Severity Index.

Authors:  A T McLellan; L Luborsky; G E Woody; C P O'Brien
Journal:  J Nerv Ment Dis       Date:  1980-01       Impact factor: 2.254

10.  Rehabilitation for adults with severe mental illness and substance use disorders. A clinical trial.

Authors:  A F Lehman; J D Herron; R P Schwartz; C P Myers
Journal:  J Nerv Ment Dis       Date:  1993-02       Impact factor: 2.254

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  11 in total

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2.  Social Support Influences on Substance Abuse Outcomes Among Sober Living House Residents with Low and Moderate Psychiatric Severity.

Authors:  Douglas L Polcin; Rachael Korcha
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3.  Social Support Networks and Symptom Severity Among Patients with Co-occurring Mental Health and Substance Use Disorders.

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Journal:  Community Ment Health J       Date:  2019-03-12

Review 4.  Does Gender Influence Outcome in Schizophrenia?

Authors:  Mary V Seeman
Journal:  Psychiatr Q       Date:  2019-03

5.  Differential Effect of Community Rehabilitation Reform on Hospitalizations of Patients with Chronic Psychotic Disorders With and Without Substance Use Disorder, Israel, 1991-2016.

Authors:  S Florentin; Y Neumark; S Raskin; T Bdolah-Abram; P Rosca
Journal:  Adm Policy Ment Health       Date:  2021-03

6.  Transition of Substance-Induced, Brief, and Atypical Psychoses to Schizophrenia: A Systematic Review and Meta-analysis.

Authors:  Benjamin Murrie; Julia Lappin; Matthew Large; Grant Sara
Journal:  Schizophr Bull       Date:  2020-04-10       Impact factor: 9.306

7.  Alcohol use disorder and its determinant factors among patients with schizophrenia attending treatment at mental specialized hospital, Addis Ababa, Ethiopia: A cross-sectional study.

Authors:  Habtamu Tadesse; Yohannes Mirkana; Tadesse Misgana
Journal:  SAGE Open Med       Date:  2021-09-28

8.  Social support and depressive symptoms: exploring stigma and self-efficacy in a moderated mediation model.

Authors:  Dong-Fang Wang; Ya-Nan Zhou; Yue-Heng Liu; Yu-Zhu Hao; Jun-Hong Zhang; Tie-Qiao Liu; Yue-Jiao Ma
Journal:  BMC Psychiatry       Date:  2022-02-15       Impact factor: 3.630

9.  Dual diagnosis competencies: A systematic review of staff training literature.

Authors:  Melissa Petrakis; Rebecca Robinson; Kevan Myers; Simon Kroes; Sarah O'Connor
Journal:  Addict Behav Rep       Date:  2018-02-02

10.  Implementation of a contingency approach for people with co-occurring substance use and psychiatric disorders: Acceptability and feasibility pilot study.

Authors:  Julie J Desrosiers; Bianief Tchiloemba; Rositsa Boyadjieva; Didier Jutras-Aswad
Journal:  Addict Behav Rep       Date:  2019-11-06
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