Literature DB >> 26287029

Recent trends in the development of vitamin B12 derivatives for medicinal applications.

Felix Zelder1.   

Abstract

This Feature Article highlights recent developments in the field of vitamin B12 derivatives for medicinal applications. The following topics are emphasized: (1) the development of aquacorrinoids for cyanide detection and detoxification, (2) the use of vitamin B12 conjugates and (3) antivitamins B12 for therapy and diagnosis, and (4) the design of corrinoids as activators of soluble guanylyl cyclase (sGC).

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Year:  2015        PMID： 26287029     DOI： 10.1039/c5cc04843e

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  9 in total

1.  Cyanide Scavenging by a Cobalt Schiff-Base Macrocycle: A Cost-Effective Alternative to Corrinoids.

Authors:  Elisenda Lopez-Manzano; Andrea A Cronican; Kristin L Frawley; Jim Peterson; Linda L Pearce
Journal:  Chem Res Toxicol       Date:  2016-05-26       Impact factor: 3.739

2.  Replacement of the Cobalt Center of Vitamin B12 by Nickel: Nibalamin and Nibyric Acid Prepared from Metal-Free B12  Ligands Hydrogenobalamin and Hydrogenobyric Acid.

Authors:  Christoph Kieninger; Klaus Wurst; Maren Podewitz; Maria Stanley; Evelyne Deery; Andrew D Lawrence; Klaus R Liedl; Martin J Warren; Bernhard Kräutler
Journal:  Angew Chem Int Ed Engl       Date:  2020-09-02       Impact factor: 15.336

3.  A CuII -Salicylidene Glycinato Complex for the Selective Fluorometric Detection of Homocysteine over 20 Proteinogenic Amino Acids.

Authors:  Xuecong Li; Prerna Yadav; Bernhard Spingler; Felix Zelder
Journal:  ChemistryOpen       Date:  2022-06       Impact factor: 2.630

4.  Solution Structure and Constrained Molecular Dynamics Study of Vitamin B12 Conjugates of the Anorectic Peptide PYY(3-36).

Authors:  Kelly E Henry; Deborah J Kerwood; Damian G Allis; Jayme L Workinger; Ron L Bonaccorso; George G Holz; Christian L Roth; Jon Zubieta; Robert P Doyle
Journal:  ChemMedChem       Date:  2016-03-30       Impact factor: 3.466

5.  Fluorophore Assisted Photolysis of Thiolato-Cob(III)alamins.

Authors:  Zachary L Rodgers; Thomas A Shell; Alexander M Brugh; Hannah L Nowotarski; Malcolm D E Forbes; David S Lawrence
Journal:  Inorg Chem       Date:  2016-02-05       Impact factor: 5.165

6.  Modulating the cobalt redox potential through imidazole hydrogen bonding interactions in a supramolecular biomimetic protein-cofactor model.

Authors:  Marjorie Sonnay; Thomas Fox; Olivier Blacque; Felix Zelder
Journal:  Chem Sci       Date:  2016-02-23       Impact factor: 9.825

7.  Systemically Administered Plant Recombinant Holo-Intrinsic Factor Targets the Liver and is not Affected by Endogenous B12 levels.

Authors:  Jayme L Workinger; Akhila N W Kuda-Wedagedara; Mara M Julin; Jordan M White; Ebba Nexo; Nerissa T Viola; Robert P Doyle
Journal:  Sci Rep       Date:  2019-08-22       Impact factor: 4.379

8.  89Zr-Cobalamin PET Tracer: Synthesis, Cellular Uptake, and Use for Tumor Imaging.

Authors:  Akhila N W Kuda-Wedagedara; Jayme L Workinger; Ebba Nexo; Robert P Doyle; Nerissa Viola-Villegas
Journal:  ACS Omega       Date:  2017-10-02

Review 9.  Antivitamins B12 -Some Inaugural Milestones.

Authors:  Bernhard Kräutler
Journal:  Chemistry       Date:  2020-11-03       Impact factor: 5.236
  9 in total

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