Literature DB >> 26283286

Toxic effects of magnesium oxide nanoparticles on early developmental and larval stages of zebrafish (Danio rerio).

Mehdi Ghobadian1, Mohammad Nabiuni2, Kazem Parivar2, Mojtaba Fathi3, Jamileh Pazooki4.   

Abstract

Magnesium oxide nanoparticles (MgONPs) are used in medicine, manufacturing and food industries. Because of their extensive application in our daily lives, environmental exposure to these nanoparticles is inevitable. The present study examined the effects of MgONPs on zebrafish (Danio rerio) early developmental stages. The results showed that, at different concentrations, MgONPs induced cellular apoptosis and intracellular reactive oxygen species. The hatching rate and survival of embryos decreased in a dose dependent manner. The 96-h LC50 value of MgONPs on zebrafish survival was 428 mg/l and the 48-h EC50 value of MgONPs on zebrafish embryo hatching rate was 175 mg/l. Moreover different types of malformation were observed in exposed embryos. The results demonstrate the toxic effects of MgONPs on zebrafish embryos and emphasize the need for further studies.
Copyright © 2015 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Fish embryos; Malformation; MgO nanoparticles; Toxicity; Zebrafish

Mesh：

Substances：

Year:  2015        PMID： 26283286     DOI： 10.1016/j.ecoenv.2015.08.009

Source DB:  PubMed          Journal:  Ecotoxicol Environ Saf        ISSN： 0147-6513            Impact factor:   6.291


  8 in total

1.  Toxicological assessment of magnesium oxide nanoparticles in HT29 intestinal cells.

Authors:  Anna Mittag; Thomas Schneider; Martin Westermann; Michael Glei
Journal:  Arch Toxicol       Date:  2019-04-15       Impact factor: 5.153

2.  Subchronic toxicity of magnesium oxide nanoparticles to Bombyx mori silkworm.

Authors:  Lin Ma; Vivian Andoh; Zhongyuan Shen; Haiyan Liu; Long Li; Keping Chen
Journal:  RSC Adv       Date:  2022-06-10       Impact factor: 4.036

Review 3.  Relation between biophysical properties of nanostructures and their toxicity on zebrafish.

Authors:  C S Martinez; D E Igartúa; M N Calienni; D A Feas; M Siri; J Montanari; N S Chiaramoni; S Del V Alonso; M J Prieto
Journal:  Biophys Rev       Date:  2017-09-07

4.  Synthesis, Characterization, and Antimicrobial Activity of Magnesium-Doped Hydroxyapatite Suspensions.

Authors:  Daniela Predoi; Simona Liliana Iconaru; Mihai Valentin Predoi; George E Stan; Nicolas Buton
Journal:  Nanomaterials (Basel)       Date:  2019-09-11       Impact factor: 5.076

5.  Particle-size dependent bactericidal activity of magnesium oxide against Xanthomonas perforans and bacterial spot of tomato.

Authors:  Y Y Liao; A Strayer-Scherer; J C White; R De La Torre-Roche; L Ritchie; J Colee; G E Vallad; J Freeman; J B Jones; M L Paret
Journal:  Sci Rep       Date:  2019-12-06       Impact factor: 4.379

6.  Exposure to Alumina Nanoparticles in Female Mice During Pregnancy Induces Neurodevelopmental Toxicity in the Offspring.

Authors:  Qinli Zhang; Yong Ding; Kaihong He; Huan Li; Fuping Gao; Taylor J Moehling; Xiaohong Wu; Jeremy Duncan; Qiao Niu
Journal:  Front Pharmacol       Date:  2018-03-20       Impact factor: 5.810

Review 7.  Zebrafish as a Model to Evaluate Nanoparticle Toxicity.

Authors:  Enamul Haque; Alister C Ward
Journal:  Nanomaterials (Basel)       Date:  2018-07-23       Impact factor: 5.076

8.  The antibacterial and angiogenic effect of magnesium oxide in a hydroxyapatite bone substitute.

Authors:  Catarina C Coelho; Tatiana Padrão; Laura Costa; Marta T Pinto; Paulo C Costa; Valentina F Domingues; Paulo A Quadros; Fernando J Monteiro; Susana R Sousa
Journal:  Sci Rep       Date:  2020-11-05       Impact factor: 4.379
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.