Rainer Gloeckl1, Inga Heinzelmann2, Stella Seeberg2, Thomas Damisch2, Wolfgang Hitzl3, Klaus Kenn4. 1. Department of Respiratory Medicine and Pulmonary Rehabilitation, Schoen Klinik Berchtesgadener Land, Schoenau am Koenigssee, Germany; Department for Prevention, Rehabilitation and Sports Medicine, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany. Electronic address: rainer.gloeckl@gmx.de. 2. Department of Respiratory Medicine and Pulmonary Rehabilitation, Schoen Klinik Berchtesgadener Land, Schoenau am Koenigssee, Germany. 3. Research Office, Paracelsus Medical University Salzburg, Salzburg, Austria. 4. Department of Respiratory Medicine and Pulmonary Rehabilitation, Schoen Klinik Berchtesgadener Land, Schoenau am Koenigssee, Germany; Department of Internal Medicine, University Hospital Marburg, Marburg, Germany.
Abstract
BACKGROUND: In recent years, some studies have shown that whole-body vibration training (WBVT) may be a beneficial training mode in patients with chronic obstructive pulmonary disease (COPD). However, the effects of WBVT in patients after lung transplantation (LTx) have not yet been investigated. METHODS:Eighty-three LTx patients (56 ± 7 years of age, 51% male, 10 ± 12 weeks post-LTx, forced expiratory volume in 1 second [FEV1] 68 ± 20 percent predicted [% pred], baseline 6-minute walk distance [6MWD] 350 ± 120 meters) admitted to a 4-week inpatientmultidisciplinary program of pulmonary rehabilitation (PR) performed supervised endurance and strength training on 5 days per week. In addition, patients were randomly assigned to 1 of 2 supervised intervention groups on 3 days/week: (1) 4 × 2 minutes of bilateral dynamic squat exercises on a side-alternating vibration platform at 24 to 26 Hz (WBVT); and (2) a control group (CON) with the same amount of exercise time on the floor. RESULTS:Seventy patients completed the study (WBVT: n = 34; CON: n = 36). Improvement in 6MWD was significantly (p = 0.029) higher in the WBVT group (83.5 meters [95% CI 65.4 to 101.7]) compared with the CON group (55.2 m [95% CI 37.5 to 72.8]). Also, peak work rate increased significantly (p = 0.042) more in the WBVT group (16.8 W [95% CI 13.5 to 20.5]) than in the CON group (12.6 W [95% CI 9.0 to 16.1]). No adverse events related to the intervention occurred during the study. CONCLUSIONS: A complementary WBVT on top of conventional endurance and strength training seems to be a feasible and safe exercise modality in patients after LTx. Furthermore, it may even enhance the benefits of a comprehensive PR on exercise capacity.
RCT Entities:
BACKGROUND: In recent years, some studies have shown that whole-body vibration training (WBVT) may be a beneficial training mode in patients with chronic obstructive pulmonary disease (COPD). However, the effects of WBVT in patients after lung transplantation (LTx) have not yet been investigated. METHODS: Eighty-three LTxpatients (56 ± 7 years of age, 51% male, 10 ± 12 weeks post-LTx, forced expiratory volume in 1 second [FEV1] 68 ± 20 percent predicted [% pred], baseline 6-minute walk distance [6MWD] 350 ± 120 meters) admitted to a 4-week inpatient multidisciplinary program of pulmonary rehabilitation (PR) performed supervised endurance and strength training on 5 days per week. In addition, patients were randomly assigned to 1 of 2 supervised intervention groups on 3 days/week: (1) 4 × 2 minutes of bilateral dynamic squat exercises on a side-alternating vibration platform at 24 to 26 Hz (WBVT); and (2) a control group (CON) with the same amount of exercise time on the floor. RESULTS: Seventy patients completed the study (WBVT: n = 34; CON: n = 36). Improvement in 6MWD was significantly (p = 0.029) higher in the WBVT group (83.5 meters [95% CI 65.4 to 101.7]) compared with the CON group (55.2 m [95% CI 37.5 to 72.8]). Also, peak work rate increased significantly (p = 0.042) more in the WBVT group (16.8 W [95% CI 13.5 to 20.5]) than in the CON group (12.6 W [95% CI 9.0 to 16.1]). No adverse events related to the intervention occurred during the study. CONCLUSIONS: A complementary WBVT on top of conventional endurance and strength training seems to be a feasible and safe exercise modality in patients after LTx. Furthermore, it may even enhance the benefits of a comprehensive PR on exercise capacity.
Authors: Felix Gerhardt; Daniel Dumitrescu; Carina Gärtner; Ralf Beccard; Thomas Viethen; Tilmann Kramer; Stephan Baldus; Martin Hellmich; Eckhard Schönau; Stephan Rosenkranz Journal: Heart Date: 2017-01-18 Impact factor: 5.994
Authors: Rainer Gloeckl; Petra Richter; Sandra Winterkamp; Michael Pfeifer; Christoph Nell; Jeffrey W Christle; Klaus Kenn Journal: ERJ Open Res Date: 2017-03-14
Authors: Rainer Gloeckl; Tessa Schneeberger; Daniela Leitl; Tobias Reinold; Christoph Nell; Inga Jarosch; Klaus Kenn; Andreas R Koczulla Journal: Respir Res Date: 2021-05-04
Authors: Lisa Wickerson; Dmitry Rozenberg; Tania Janaudis-Ferreira; Robin Deliva; Vincent Lo; Gary Beauchamp; Denise Helm; Chaya Gottesman; Polyana Mendes; Luciana Vieira; Margaret Herridge; Lianne G Singer; Sunita Mathur Journal: World J Transplant Date: 2016-09-24
Authors: Ruud H Knols; Nicolas Fischer; Dario Kohlbrenner; Anastasios Manettas; Eling D de Bruin Journal: Front Physiol Date: 2018-07-20 Impact factor: 4.566
Authors: Vasileios Andrianopoulos; Rainer Gloeckl; Martina Boensch; Katharina Hoster; Tessa Schneeberger; Inga Jarosch; Rembert A Koczulla; Klaus Kenn Journal: ERJ Open Res Date: 2019-09-16