Literature DB >> 26277854

A Long-Term Study to Evaluate Acidic Skin Care Treatment in Nursing Home Residents: Impact on Epidermal Barrier Function and Microflora in Aged Skin.

Jürgen Blaak1, Olaf Kaup, Willi Hoppe, Gabriele Baron-Ruppert, Heiko Langheim, Peter Staib, Rainer Wohlfart, Dieter Lüttje, Nanna Schürer.   

Abstract

BACKGROUND: The pH of the stratum corneum (SC) in the elderly is elevated and linked to impaired SC function. Therefore, this paper addresses the question of whether acidic skin care generates positive clinical, biophysical, and microbiological effects in aged skin.
METHODS: This study was performed to assess skin care effects in nursing home residents (aged 80-97 years). Visual, biophysical, and microbiological methods were used. Subjects were randomly assigned to 1 of 2 groups and treated over 7 weeks with skin care products adjusted to a pH of 4.0 (group A) or a pH of 6.0 (group B).
RESULTS: Compared to baseline, SC integrity improved significantly in group A (p = 0.007), whereas there was no change in group B (p = 0.672). SC recovery 24 h after perturbation increased significantly in group A (p = 0.004) compared to baseline. The SC recovery in group B was not significant compared to baseline (p = 0.327).
CONCLUSION: Long-term treatment with pH 4.0 skin care results in a significant improvement in epidermal barrier function compared to identical products with a pH of 6.0. In addition, effects on skin dryness and resident flora were demonstrated, but without significant differences, between the 2 groups. Based on these results, we recommend adjustment of skin care products for the elderly to a pH of 4.0 to maintain the health of aged skin.
© 2015 S. Karger AG, Basel.

Entities:  

Year:  2015        PMID: 26277854     DOI: 10.1159/000437212

Source DB:  PubMed          Journal:  Skin Pharmacol Physiol        ISSN: 1660-5527            Impact factor:   3.479


  2 in total

1.  Hygiene and emollient interventions for maintaining skin integrity in older people in hospital and residential care settings.

Authors:  Fiona Cowdell; Yuri T Jadotte; Steven J Ersser; Simon Danby; Sandra Lawton; Amanda Roberts; Judith Dyson
Journal:  Cochrane Database Syst Rev       Date:  2020-01-23

2.  Impact of a pH 5 Oil-in-Water Emulsion on Skin Surface pH.

Authors:  Theresa Fürtjes; Katharina T Weiss; Alexander Filbry; Frank Rippke; Stephan Schreml
Journal:  Skin Pharmacol Physiol       Date:  2017-10-04       Impact factor: 3.479

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.