| Literature DB >> 2627196 |
Abstract
A genetic polymorphism of beta-chain rabbit (Oryctolagus cuniculus) hemoglobin is demonstrated by means of acid starch gel electrophoresis. The biochemical evidence presented suggests that a previously reported substitution of a neutral amino acid for a histidine is responsible for the detected genetic variation. Segregation analysis was performed in a sample of 15 matings with 49 offspring and confirmed the genetic hypothesis: two common alleles at an autosomal locus. The calculated gene frequencies in a random sample of 125 individuals are HBB*1 = 0.48 and HBB*2 = 0.52.Entities:
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Year: 1989 PMID: 2627196 DOI: 10.1007/bf02396059
Source DB: PubMed Journal: Biochem Genet ISSN: 0006-2928 Impact factor: 1.890