Literature DB >> 2383241

Biochemical and genetic studies on rabbit hemoglobin. II. Electrophoretic polymorphism of the alpha-chain.

N Ferrand1.   

Abstract

A genetic polymorphism of rabbit (Oryctolagus cuniculus) hemoglobin alpha chain is demonstrated by means of acid starch gel electrophoresis. The polymorphism is not detected by isoelectric focusing and may be based upon neutral for neutral amino acid substitutions in accordance with previous findings by means of amino acid sequencing. Segregation analysis was performed on 15 matings with 49 offspring and confirmed the initial genetic hypothesis of three common codominant alleles at an autosomal locus. The calculated gene frequencies in a random sample of 86 unrelated individuals are HBA*1 = 0.73, HBA*2 = 0.22, and HBA*3 = 0.05.

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Year:  1990        PMID: 2383241     DOI: 10.1007/bf00561331

Source DB:  PubMed          Journal:  Biochem Genet        ISSN: 0006-2928            Impact factor:   1.890


  9 in total

1.  An isoleucine-valine substitution in the beta chain of rabbit hemoglobin.

Authors:  J Bricker; M D Garrick
Journal:  Biochim Biophys Acta       Date:  1974-06-07

2.  Characterization by polyacrylamide gel electrophoresis of hemoglobins in rabbit embryo, fetus, and adult.

Authors:  I McIlwaine; D Rodbard; A Chrambach
Journal:  Anal Biochem       Date:  1973-10       Impact factor: 3.365

3.  Polymorphic alleles of the gene for the beta-chain of rabbit haemoglobin.

Authors:  A Galizzi
Journal:  Nat New Biol       Date:  1971-02-03

4.  The amino acid sequence of the beta-chains of rabbit hemoglobin.

Authors:  A Galizzi
Journal:  Eur J Biochem       Date:  1970-11

5.  Allelic variants in the amino-acid sequence of the alpha chain of rabbit haemoglobin.

Authors:  T Hunter; A Munro
Journal:  Nature       Date:  1969-09-20       Impact factor: 49.962

6.  Trnaslational variations in the amino acid sequence of the alpha-chain of rabbit hemoglobin.

Authors:  G von Ehrenstein
Journal:  Cold Spring Harb Symp Quant Biol       Date:  1966

7.  Separator isoelectric focusing: an improved method of protein analysis and purification.

Authors:  M L Caspers; Y Posey; R K Brown
Journal:  Anal Biochem       Date:  1977-05-01       Impact factor: 3.365

8.  An electrophoretically silent polymorphism for the beta chains of rabbit hemoglobin and associated polyribosome patterns.

Authors:  M D Garrick; J Bricker; L M Garrick
Journal:  Genetics       Date:  1974-01       Impact factor: 4.562

9.  Biochemical and genetic studies on rabbit hemoglobin. I. Electrophoretic polymorphism of the beta chain.

Authors:  N Ferrand
Journal:  Biochem Genet       Date:  1989-12       Impact factor: 1.890

  9 in total
  3 in total

1.  Genetic diversity in the Chinese pangolin (Manis pentadactyla) inferred from protein electrophoresis.

Authors:  B Su; R Q Liu; Y X Wang; L M Shi
Journal:  Biochem Genet       Date:  1994-10       Impact factor: 1.890

2.  Evidence for contrasting modes of selection at interacting globin genes in the European rabbit (Oryctolagus cuniculus).

Authors:  R Campos; J F Storz; N Ferrand
Journal:  Heredity (Edinb)       Date:  2008-04-30       Impact factor: 3.821

3.  The molecular basis of high-altitude adaptation in deer mice.

Authors:  Jay F Storz; Stephen J Sabatino; Federico G Hoffmann; Eben J Gering; Hideaki Moriyama; Nuno Ferrand; Bruno Monteiro; Michael W Nachman
Journal:  PLoS Genet       Date:  2007-02-13       Impact factor: 5.917

  3 in total

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