PURPOSE: To report survival outcomes and local control in patients with solitary fibrous tumors (SFT) treated using surgery and radiation therapy (RT). METHODS: We reviewed the medical records of 31 consecutive patients definitively treated for SFT with surgery and RT between 1982 and 2012. The median age was 51 years (range, 23 to 88 y) and tumors were evenly distributed between the head and neck (n=9, 29%), trunk (n=10, 32%), and lower extremities (n=9, 29%). The majority of tumors were large (>5 cm) (n=23, 72%). Specimens had a median of 2 mitoses/10 HPF (range, 0 to 8). Nearly half the cases were treated with postoperative RT (n=14, 45%; median dose, 58 Gy) and the other 17 patients (55%) received preoperative RT (median dose, 50 Gy). RESULTS: Median follow-up time was 59 months (range, 18 to 349 mo). The 5-year rates of local control, overall survival, and distant metastatic-free survival were 100%, 95%, and 92%, respectively. There were no local or nodal relapses and the 10-year complication rate was 6% (n=2). CONCLUSIONS: Treatment of soft tissue SFT using combined surgery and RT results in excellent local control.
PURPOSE: To report survival outcomes and local control in patients with solitary fibrous tumors (SFT) treated using surgery and radiation therapy (RT). METHODS: We reviewed the medical records of 31 consecutive patients definitively treated for SFT with surgery and RT between 1982 and 2012. The median age was 51 years (range, 23 to 88 y) and tumors were evenly distributed between the head and neck (n=9, 29%), trunk (n=10, 32%), and lower extremities (n=9, 29%). The majority of tumors were large (>5 cm) (n=23, 72%). Specimens had a median of 2 mitoses/10 HPF (range, 0 to 8). Nearly half the cases were treated with postoperative RT (n=14, 45%; median dose, 58 Gy) and the other 17 patients (55%) received preoperative RT (median dose, 50 Gy). RESULTS: Median follow-up time was 59 months (range, 18 to 349 mo). The 5-year rates of local control, overall survival, and distant metastatic-free survival were 100%, 95%, and 92%, respectively. There were no local or nodal relapses and the 10-year complication rate was 6% (n=2). CONCLUSIONS: Treatment of soft tissue SFT using combined surgery and RT results in excellent local control.
Authors: Giuseppe Bianchi; Andrea Sambri; Elena Pedrini; Laura Pazzaglia; Luca Sangiorgi; Poosit Ruengwanichayakun; Davide Donati; Maria Serena Benassi; Alberto Righi Journal: Virchows Arch Date: 2019-08-28 Impact factor: 4.064
Authors: Rick L Haas; Iris Walraven; Estelle Lecointe-Artzner; Winan J van Houdt; Dirk Strauss; Yvonne Schrage; Andrew J Hayes; Chandrajit P Raut; Mark Fairweather; Elizabeth H Baldini; Alessandro Gronchi; Laura De Rosa; Anthony M Griffin; Peter C Ferguson; Jay Wunder; Michiel A J van de Sande; Augustinus D G Krol; Jacus Skoczylas; Claudia Sangalli; Silvia Stacchiotti Journal: Cancer Date: 2020-04-21 Impact factor: 6.860
Authors: Erin A Kaya; Jonathan D Carlson; Cheddhi J Thomas; Aaron E Wagner; Robert K Fairbanks; Wayne T Lamoreaux; Christopher M Lee Journal: Case Rep Med Date: 2020-04-07
Authors: Bahil Ghanim; Sebastian Hess; Pietro Bertoglio; Ali Celik; Aynur Bas; Felicitas Oberndorfer; Franca Melfi; Alfredo Mussi; Walter Klepetko; Christine Pirker; Walter Berger; Imrich Harmati; Attila Farkas; Hendrik Jan Ankersmit; Balazs Dome; Janos Fillinger; Clemens Aigner; Balazs Hegedus; Ferenc Renyi-Vamos; György Lang Journal: Sci Rep Date: 2017-10-02 Impact factor: 4.379