Literature DB >> 26268079

[TRIGLYCERIDE LEVELS AS A RISK FACTOR DURING PREGNANCY; BIOLOGICAL MODELING; SYSTEMATIC REVIEW].

María José Aguilar Cordero1, Laura Baena García2, Antonio Manuel Sánchez López2, Rafael Guisado Barrilao1, Enrique Hermoso Rodríguez3, Norma Mur Villar4, Manuel Capel Tuñón5.   

Abstract

INTRODUCTION: introduction: Some of the diseases that can appear in pregnancy (gestational diabetes, hypertension and preeclampsia) are being associated with an increased risk of heart throughout life diseases. This should be present in future assessments of the health of women. One of the most important biomarkers in cardiovascular diseases is the triglyceride level, and that undergoes a significant change during pregnancy.
OBJECTIVE: the objective of this review is to analyze the studies that have investigated triglyceride levels during pregnancy as a risk factor for cardiovascular disease in the last weeks of pregnancy and childbirth.
METHODS: a systematic search was made and 14 specific articles on the subject were selected following the PRISMA guidelines.
RESULTS: in normal pregnancy decreased the level of lipids in the first weeks, followed by a gradual increase. Especially high from the 12th week of gestation. This increase in plasma levels of circulating lipids occurs linearly, reaching a peak a few days before delivery. This increase results because of the increased estrogen levels and insulin resistance. It has also been associated with prolactin levels.
CONCLUSIONS: through this review, it has been able to demonstrate the relationship of elevated triglycerides some pathologies or more frequent changes in risk pregnancies, in which a significantly higher elevation occurs compared to normal pregnancies. It is in this context that the biological modeling may be particularly important, facilitating the creation of models and percentile curves applicable to the population, and allow monitoring of changes in triglycerides, which end up pointing situations passing be predictors of a potentially pathological situation. Thus, appropriate interventions would be carried rafter more briefly, and see so favored adequate primary prevention. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

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Year:  2015        PMID: 26268079     DOI: 10.3305/nh.2015.32.2.9215

Source DB:  PubMed          Journal:  Nutr Hosp        ISSN: 0212-1611            Impact factor:   1.057


  3 in total

Review 1.  Dyslipidemia Management in Pregnancy: Why Is It not Covered in the Guidelines?

Authors:  Joanna Lewek; Maciej Banach
Journal:  Curr Atheroscler Rep       Date:  2022-04-30       Impact factor: 5.967

2.  The association between HIV (treatment), pregnancy serum lipid concentrations and pregnancy outcomes: a systematic review.

Authors:  Marissa J Harmsen; Joyce L Browne; Francois Venter; Kerstin Klipstein-Grobusch; Marcus J Rijken
Journal:  BMC Infect Dis       Date:  2017-07-11       Impact factor: 3.090

3.  Consecutive reference intervals for biochemical indices related to serum lipid levels and renal function during normal pregnancy.

Authors:  Lina Wu; Qijun Wu; Qiang Li; Shuang Cao; Yue Zhang; Yong Liu; Xiaosong Qin
Journal:  BMC Pregnancy Childbirth       Date:  2022-08-15       Impact factor: 3.105

  3 in total

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