Literature DB >> 26266182

Sinonasal Neoplasia - Clinicopathological Profile And Importance of Computed Tomography.

Jaiganesh Sivalingam1, Radha Sarawagi2, Sameer Raghuwanshi3, Pankaj Kumar Yadav4.   

Abstract

BACKGROUND: Nasal cavity and Paranasal sinus malignancies are very rare, in which maxillary sinus is the commonest, followed by ethmoid, frontal and sphenoid sinus. Computed Tomography (CT) & Magnetic Resonance Imaging (MRI) play a key role in diagnosis, staging and management of paranasal sinuses and nasal pathologies. Multiplanar imaging in CT helps better imaging of critical anatomical areas. Aim of our study was to study the incidence, clinical features, CT features and its importance in the management of sinonasal neoplasms.
MATERIALS AND METHODS: This prospective study was carried out in a tertiary care hospital of MP, India. Consecutive 40 histologically proven cases of sinonasal neoplasia who visited the Department of Otorhinolaryngology and Radiotherapy are included in our study. Demography and clinical features were recorded. Cases of nasal and paranasal sinus masses diagnosed on CT attending ENT and Radiotherapy OPD or admitted in the Radiotherapy ward forms the material of this study. This included patients of both sexes and all ages. Histopathological examination was asked to confirm the diagnosis made on CT.
RESULTS: There were total 40 cases of sinonasal neoplasia among which 24 were benign. Almost all the benign cases were seen in the age group <40 y with mean age of 20 y and most of the malignant cases were seen in the age group above 40 y with mean age of 55 y. In our study we found male preponderance with male female ratio of 4:1 in both benign and malignant conditions. The commonest presenting symptoms of the patients with sinonasal masses in our study was nasal obstruction (75%) and nasal discharge (67.5%) followed by nasal mass (65%), epistaxis (62.5%) and headache (60%). Angiofibroma and papilloma were the commonest benign lesions. Commonest malignant lesion was squamous cell carcinoma. Of the malignant Sinonasal tumours studied in our series, maxillary sinus was involved in 13, ethmoid sinuses and nasal cavity in 10 cases each, and frontal sinuses in 2 cases.
CONCLUSION: Contrast enhanced computed tomography with multiplanar reconstruction is an excellent modality for imaging sinonasal masses. CT can define the character of the sinonasal mass, thus differentiating benign from malignant. CT helps better imaging of critical anatomical areas and helpful in planning treatment procedures such as surgery and radiotherapy.

Entities:  

Keywords:  Benign; Malignant; Paranasal sinuses

Year:  2015        PMID: 26266182      PMCID: PMC4525572          DOI: 10.7860/JCDR/2015/13514.6026

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  9 in total

1.  Clinicopathological study of non-neoplastic lesions of nasal cavity and paranasal sinuses.

Authors:  U Zafar; N Khan; N Afroz; S A Hasan
Journal:  Indian J Pathol Microbiol       Date:  2008 Jan-Mar       Impact factor: 0.740

2.  Primary extranodal Non-Hodgkin lymphoma of the orbital and paranasal region-a retrospective study.

Authors:  Annett Sandner; Alexey Surov; Andreas Gunter Bach; Sabrina Kösling
Journal:  Eur J Radiol       Date:  2012-10-23       Impact factor: 3.528

3.  Carcinoma of the nasal cavity and paranasal sinuses in Denmark 1995-2004.

Authors:  Christian Thorup; Lars Sebbesen; Hella Danø; Michael Leetmaa; M Andersen; Christian Buchwald; Claus A Kristensen; Jens Bentzen; Christian Godballe; Jørgen Johansen; Cai Grau
Journal:  Acta Oncol       Date:  2010-04       Impact factor: 4.089

4.  Factors affecting survival in maxillary sinus cancer.

Authors:  Neil Bhattacharyya
Journal:  J Oral Maxillofac Surg       Date:  2003-09       Impact factor: 1.895

5.  Adult rhabdomyosarcoma: cross-sectional imaging findings including histopathologic correlation.

Authors:  Steven D Allen; Eleanor C Moskovic; Cyril Fisher; J Meirion Thomas
Journal:  AJR Am J Roentgenol       Date:  2007-08       Impact factor: 3.959

6.  Focal hyperostosis on CT of sinonasal inverted papilloma as a predictor of tumor origin.

Authors:  D K Lee; S K Chung; H-J Dhong; H Y Kim; H-J Kim; K H Bok
Journal:  AJNR Am J Neuroradiol       Date:  2007-04       Impact factor: 3.825

7.  Clinico-pathological profile of sinonasal masses: a study from a tertiary care hospital of India.

Authors:  A Lathi; M M A Syed; P Kalakoti; D Qutub; S P Kishve
Journal:  Acta Otorhinolaryngol Ital       Date:  2011-12       Impact factor: 2.124

Review 8.  Imaging of sinonasal tumours.

Authors:  Heidi B Eggesbø
Journal:  Cancer Imaging       Date:  2012-05-07       Impact factor: 3.909

9.  Imaging in the diagnosis of juvenile nasopharyngeal angiofibroma.

Authors:  Satyaranjan Mishra; N M Praveena; Rajat Golakh Panigrahi; Y Mogit Gupta
Journal:  J Clin Imaging Sci       Date:  2013-03-22
  9 in total
  3 in total

1.  Imaging Appearance of SMARCB1 (INI1)-Deficient Sinonasal Carcinoma: A Newly Described Sinonasal Malignancy.

Authors:  D R Shatzkes; L E Ginsberg; M Wong; A H Aiken; B F Branstetter; M A Michel; N Aygun
Journal:  AJNR Am J Neuroradiol       Date:  2016-07-07       Impact factor: 3.825

2.  Prospective Study to Evaluate the Role of Multidetector Computed Tomography in Evaluation of Paranasal Sinus Pathologies.

Authors:  Tarim Usmani; Eram Fatima; Vivek Raj; Kashish Aggarwal
Journal:  Cureus       Date:  2022-04-10

Review 3.  Malignant Sinonasal Tumors: Update on Histological and Clinical Management.

Authors:  Alessandra Bracigliano; Fabiana Tatangelo; Francesco Perri; Giuseppe Di Lorenzo; Roberto Tafuto; Alessandro Ottaiano; Ottavia Clemente; Maria Luisa Barretta; Nunzia Simona Losito; Mariachiara Santorsola; Salvatore Tafuto
Journal:  Curr Oncol       Date:  2021-07-01       Impact factor: 3.677

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.