Literature DB >> 26259685

Fat may affect magnetic resonance signal intensity and brain tissue volumes.

Anderson Mon1, Christoph Abé2, Timothy C Durazzo3, Dieter J Meyerhoff3.   

Abstract

Obesity/overweight is reported to affect MR-measured brain tissue volume and white matter (WM) signal intensity. This study investigated possible effects of fat on these measures, using pig fat on three participants at a 4T magnet. Grey matter volumes in the presence of fat were lower than baseline measures. Total WM volumes in the presence of fat were higher than baseline measures. WM hypo-intensities on T1-weighted images were higher in the presence of fat than baseline measures. Therefore physical effects of head fat of obese/overweight individual may at least, partly contribute to the association of obesity/overweight with MR structural measures.
Copyright © 2015 Asia Oceania Association for the Study of Obesity. All rights reserved.

Entities:  

Keywords:  Fat; Grey matter; Magnetic resonance signal hypo-intensity; Obesity; White matter

Mesh：

Year:  2015        PMID： 26259685      PMCID： PMC4876040          DOI： 10.1016/j.orcp.2015.07.009

Source DB:  PubMed          Journal:  Obes Res Clin Pract        ISSN： 1871-403X            Impact factor:   2.288


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