| Literature DB >> 26255809 |
Anna A Popova1, Sebastian M Schillo2, Konstantin Demir1, Erica Ueda1, A Nesterov-Mueller2, Pavel A Levkin1.
Abstract
A droplet-array (DA) sandwich chip is a miniaturized platform for cell-based high-throughput screening. It is based on sandwiching of a glass slide with a preprinted library and a superhydrophobic-superhydrophilic pattern, which consists of thousands of simultaneously formed microdroplets containing cells. The DA sandwich chip allows for one-step cell seeding, simultaneous initiation of screening, and 1000 times less reagent consumption than a regular 96-well plate.Keywords: droplet-array sandwich chips; high throughput screening; superhydrophobic-superhydrophilic micropatterning
Mesh:
Year: 2015 PMID: 26255809 DOI: 10.1002/adma.201502115
Source DB: PubMed Journal: Adv Mater ISSN: 0935-9648 Impact factor: 30.849