Literature DB >> 26254724

High Grade Blunt Renal Trauma: Predictors of Surgery and Long-Term Outcomes of Conservative Management. A Prospective Single Center Study.

Cecilia Lanchon1, Gaëlle Fiard1, Valentin Arnoux1, Jean-Luc Descotes1, Jean-Jacques Rambeaud1, Nicolas Terrier1, Bernard Boillot1, Caroline Thuillier1, Delphine Poncet1, Jean-Alexandre Long2.   

Abstract

PURPOSE: The management of major renal trauma has shifted in the last decade in favor of a nonoperative approach. Our level 1 trauma center promotes this approach with the objective of renal function preservation. However, certain situations still require surgery. In this study we analyze predictors of surgery and long-term outcomes after conservative management.
MATERIALS AND METHODS: From January 2004 to March 2015 we prospectively collected data from all patients admitted to our institution for high grade blunt renal trauma (grades IV and V). Nonoperative management was considered successful when patients did not undergo surgical exploration, regardless of angioembolization or endoscopic treatment.
RESULTS: Of 306 patients with renal trauma 151 presented with major injuries, including 124 grade IV and 27 grade V. Nonoperative management was successful in 110 (89%) cases of grade IV and 14 (52%) cases of grade V lesions. Deceleration mechanism (p=0.03), associated lesions (p=0.001), percentage of devitalized parenchyma (p=0.012), angioembolization (p <0.001), hemodynamic instability (p <0.001) and low hemoglobin (p=0.001) were more frequent in patients treated surgically. On multivariate analysis grade (OR 7.36, p=0.01) and hemodynamic instability (OR 4.18, p=0.04) were the only independent predictors of surgical treatment. Long-term followup of preserved kidneys revealed a remaining 40% and 0% relative renal function after grade IV and V injuries, respectively. Only devascularized parenchyma greater than 25% predicted the decline of long-term renal function.
CONCLUSIONS: Nonoperative management can and should be performed safely in cases of grade IV injuries whenever possible, with valuable long-term renal function. It can also be initiated in grade V cases. However, surgeons should consider nephrectomy with the onset of any suspicious symptoms.
Copyright © 2016 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  embolization; endoscopy; kidney; therapeutic; wounds and injuries

Mesh:

Year:  2015        PMID: 26254724     DOI: 10.1016/j.juro.2015.07.100

Source DB:  PubMed          Journal:  J Urol        ISSN: 0022-5347            Impact factor:   7.450


  13 in total

1.  Conservative Management of High-grade Renal Trauma Does Not Lead to Prolonged Hospital Stay.

Authors:  Lindsay A Hampson; Kushan D Radadia; Anobel Y Odisho; Jack W McAninch; Benjamin N Breyer
Journal:  Urology       Date:  2018-04-02       Impact factor: 2.649

Review 2.  The American Association for the Surgery of Trauma Organ Injury Scale 2018 update for computed tomography-based grading of renal trauma: a primer for the emergency radiologist.

Authors:  Ling-Chen Chien; Mona Vakil; Jonathan Nguyen; Amanda Chahine; Krystal Archer-Arroyo; Tarek N Hanna; Keith D Herr
Journal:  Emerg Radiol       Date:  2019-09-05

3.  Utility of MDCT findings in predicting patient management outcomes in renal trauma.

Authors:  Arthur H Baghdanian; Armonde A Baghdanian; Anthony Armetta; Richard K Babayan; Christina A LeBedis; Jorge A Soto; Stephan W Anderson
Journal:  Emerg Radiol       Date:  2016-12-21

Review 4.  Renal trauma: the current best practice.

Authors:  Tomer Erlich; Noam D Kitrey
Journal:  Ther Adv Urol       Date:  2018-07-10

5.  High grade renal trauma management: a survey of practice patterns and the perceived need for a prospective management trial.

Authors:  Rachel A Moses; Ross E Anderson; Sorena Keihani; James M Hotaling; Raminder Nirula; Daniel J Vargo; Jeremy B Myers
Journal:  Transl Androl Urol       Date:  2019-08

6.  The effect of biological sealants and adhesive treatments on matrix metalloproteinase expression during renal injury healing.

Authors:  José Miguel Lloris-Carsí; Carlos Barrios; Beatriz Prieto-Moure; José Miguel Lloris-Cejalvo; Dolores Cejalvo-Lapeña
Journal:  PLoS One       Date:  2017-05-11       Impact factor: 3.240

7.  Incidence of urinary extravasation and rate of ureteral stenting after high-grade renal trauma in adults: a meta-analysis.

Authors:  Sorena Keihani; Ross E Anderson; Michelle Fiander; Mary M McFarland; Gregory J Stoddard; James M Hotaling; Jeremy B Myers
Journal:  Transl Androl Urol       Date:  2018-05

Review 8.  Use of angioembolization in urology: a review.

Authors:  Kirkpatrick B Fergus; Nima Baradaran; Anas Tresh; Miles B Conrad; Benjamin N Breyer
Journal:  Transl Androl Urol       Date:  2018-08

Review 9.  Kidney and uro-trauma: WSES-AAST guidelines.

Authors:  Federico Coccolini; Ernest E Moore; Yoram Kluger; Walter Biffl; Ari Leppaniemi; Yosuke Matsumura; Fernando Kim; Andrew B Peitzman; Gustavo P Fraga; Massimo Sartelli; Luca Ansaloni; Goran Augustin; Andrew Kirkpatrick; Fikri Abu-Zidan; Imitiaz Wani; Dieter Weber; Emmanouil Pikoulis; Martha Larrea; Catherine Arvieux; Vassil Manchev; Viktor Reva; Raul Coimbra; Vladimir Khokha; Alain Chichom Mefire; Carlos Ordonez; Massimo Chiarugi; Fernando Machado; Boris Sakakushev; Junichi Matsumoto; Ron Maier; Isidoro di Carlo; Fausto Catena
Journal:  World J Emerg Surg       Date:  2019-12-02       Impact factor: 5.469

10.  A Comparative Study of Conservation, Endovascular Embolization Therapy, and Surgery for Blunt Renal Trauma.

Authors:  Hao Xu; Xuli Min; Yugen Li; Lin Yang; Yongjun Ren
Journal:  Med Sci Monit       Date:  2020-05-06
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