Antonio Augusto Santos Paulo1,2, Maria Helena Ruivo Solheiro3, Carolina Oliveira Santos Paulo4, Vera Mónica Almeida Afreixo5. 1. Department of Obstetrics and Gynecology, Hospital Centre Tondela-Viseu, Avda. Rei D.Duarte, 3504-509, Viseu, Portugal. antoniosantospaulo@sapo.pt. 2. Health Sciences Department, University of Aveiro, Aveiro, Portugal. antoniosantospaulo@sapo.pt. 3. Department of Obstetrics and Gynecology, Hospital Centre Tondela-Viseu, Viseu, Portugal. 4. Farmacia Avenida, Mangualde, Portugal. 5. Department of Mathematics and Institute of Biomedicine, University of Aveiro, Aveiro, Portugal.
Abstract
BACKGROUND: Mini-hysteroscopy is believed to be pain-free or in the least bearable. Office procedures are therefore usually performed without analgesia or anesthesia. Is it indeed as tolerable as papers and authors suggest? OBJECTIVES: To estimate what proportion of women reports moderate to severe discomfort during examination using the smaller diameter scopes. SEARCH STRATEGY: Online sources were search with key words "hysteroscopy" and "pain" from 2000 to December 2014. Thirty-five articles were retrieved for detailed analysis. SELECTION CRITERIA: Randomized controlled trials (RCT) and well-designed prospective trials (PT) studying pain as main outcome, in office mini-hysteroscopy in at least one arm. Studies or arms within a study where conscientious sedation, anesthesia, or non-steroidal drugs were used were excluded. Chosen data collected was the number of women referring moderate to severe pain compared to total women with intervention in the arm or study. Authors were contacted to try to retrieve unpublished data for analysis. DATA COLLECTION AND ANALYSIS: We performed a meta-analysis from eight studies (six RCT and two PT) comparing pain reported as moderate or severe to total women in mini-hysteroscopy. MAIN RESULTS: A meta-analysis estimated the pooled prevalence of pain (>3-10 on 10 cm visual analog scale) for all studies and by two subgroups: (1) RCT and (2) PT. Due to significant heterogeneity between studies, we used the random effects model. Results revealed a high prevalence of pain in outpatient mini-hysteroscopy. CONCLUSIONS: Office mini-hysteroscopy is painful.
BACKGROUND: Mini-hysteroscopy is believed to be pain-free or in the least bearable. Office procedures are therefore usually performed without analgesia or anesthesia. Is it indeed as tolerable as papers and authors suggest? OBJECTIVES: To estimate what proportion of women reports moderate to severe discomfort during examination using the smaller diameter scopes. SEARCH STRATEGY: Online sources were search with key words "hysteroscopy" and "pain" from 2000 to December 2014. Thirty-five articles were retrieved for detailed analysis. SELECTION CRITERIA: Randomized controlled trials (RCT) and well-designed prospective trials (PT) studying pain as main outcome, in office mini-hysteroscopy in at least one arm. Studies or arms within a study where conscientious sedation, anesthesia, or non-steroidal drugs were used were excluded. Chosen data collected was the number of women referring moderate to severe pain compared to total women with intervention in the arm or study. Authors were contacted to try to retrieve unpublished data for analysis. DATA COLLECTION AND ANALYSIS: We performed a meta-analysis from eight studies (six RCT and two PT) comparing pain reported as moderate or severe to total women in mini-hysteroscopy. MAIN RESULTS: A meta-analysis estimated the pooled prevalence of pain (>3-10 on 10 cm visual analog scale) for all studies and by two subgroups: (1) RCT and (2) PT. Due to significant heterogeneity between studies, we used the random effects model. Results revealed a high prevalence of pain in outpatient mini-hysteroscopy. CONCLUSIONS: Office mini-hysteroscopy is painful.
Authors: J Carugno; G Grimbizis; M Franchini; L Alonso; L Bradley; R Campo; U Catena; C De Angelis; A Di Spiezio Sardo; M Farrugia; S Haimovich; K Isaacson; N Moawad; E Saridogan; T J Clark Journal: Facts Views Vis Obgyn Date: 2021-10-13
Authors: Andréa Pegoraro; Marcelo Ettruri Santos; Jean Tetsuo Takamori; Waldemar de Almeida Pereira de Carvalho; Renato de Oliveira; Caio Parente Barbosa; Ângela van Nimwegen Journal: Einstein (Sao Paulo) Date: 2019-12-13
Authors: Magdalena M Biela; Jacek Doniec; Monika Szafarowska; Kamil Sobocinski; Andrzej Kwiatkowski; Paweł Kamiński Journal: Wideochir Inne Tech Maloinwazyjne Date: 2019-11-05 Impact factor: 1.195