Literature DB >> 26249709

Observations on Attenuation of Local Electrogram Amplitude and Circuit Impedance During Atrial Radiofrequency Ablation: An In vivo Investigation Using a Novel Direct Endocardial Visualization Catheter.

Abhishek Bhaskaran1,2, William Chik1,2, Chrishan Nalliah1, Jim Pouliopoulos1,2, Tony Barry1,2,3, Doan Trang Nguyen2,3, Christine Midekin1, Rahul Samanta1, Melad Farraha1,2, Stuart Thomas1,2, Pramesh Kovoor1,2, Aravinda Thiagalingam1,2.   

Abstract

AIMS: To define the temporal characteristics of atrial lesion growth (lesion surface area), local electrogram amplitude attenuation, and circuit impedance decrement during in vivo radiofrequency (RF) ablation with direct endocardial visualization (DEV). METHODS AND
RESULTS: A direct endocardial visualization catheter was used for real-time endoscopic visualization of atrial endocardial surface during RF ablation. Videos of lesion growth (surface area), circuit impedance, and local electrogram amplitude were recorded during ablation in 11 ovine. Fifty-two atrial ablations at 12 W, 14 W, and 16 W power for 30 seconds were analyzed. During 30-second RF ablation, the lesion matured (90% of final lesion dimension) in the first 23.0 ± 5.8 seconds. The local electrogram amplitude attenuation (80% decrement) and circuit impedance attenuation (20% decrement from initial) occurred 13.8 ± 8.2 seconds and 13.1 ± 7.9 seconds, respectively, before lesion maturity in a significant proportion of 30 second atrial ablations.
CONCLUSION: The DEV observations suggest that in smooth atrial surface ablations with significant local electrogram and impedance decrement in the first 10 seconds, further extension of ablation for 10-15 seconds could deliver optimal surface dimensions; however, real-time measurement of depth was not possible.
© 2015 Wiley Periodicals, Inc.

Entities:  

Keywords:  ablation efficacy; ablation safety ablation timing; atrial ablation; direct endocardial visualization; impedance decrement; local electrogram amplitude decrement; radiofrequency ablation

Year:  2015        PMID: 26249709     DOI: 10.1111/jce.12774

Source DB:  PubMed          Journal:  J Cardiovasc Electrophysiol        ISSN: 1045-3873


  3 in total

1.  'CLOSE'-Guided Pulmonary Vein Isolation and Changes in Local Bipolar and Unipolar Atrial Electrograms: Observations from the EP Lab.

Authors:  Mathieu Coeman; Milad El Haddad; Michael Wol; Rajin Choudhury; Yves Vandekerckhove; Rajin Choudhury; Sebastien Knecht; Rene Tavernier; Mattias Duytschaever
Journal:  J Atr Fibrillation       Date:  2018-02-28

Review 2.  Impedance-guided Radiofrequency Ablation: Using Impedance to Improve Ablation Outcomes.

Authors:  Jason S Chinitz; Gregory F Michaud; Kent Stephenson
Journal:  J Innov Card Rhythm Manag       Date:  2017-10-15

3.  Impact of impedance decrease during radiofrequency current application for atrial fibrillation ablation on myocardial lesion and gap formation.

Authors:  Osamu Inaba; Yasutoshi Nagata; Masahiro Sekigawa; Naoyuki Miwa; Junji Yamaguchi; Takamichi Miyamoto; Masahiko Goya; Kenzo Hirao
Journal:  J Arrhythm       Date:  2018-04-16
  3 in total

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