| Literature DB >> 26247461 |
Zohar Yehoshua, Carlos Alexandre de Amorim Garcia Filho, Renata Portella Nunes, Giovanni Gregori, Fernando M Penha, Andrew A Moshfeghi, Hongrong Luo, Zhang Kang, SriniVas Sadda, William Feuer, Philip J Rosenfeld.
Abstract
The association between the growth of geographic atrophy (GA) and a single nucleotide polymorphism (SNP) in the complement factor I (CFI) locus was investigated in the COMPLETE trial. Growth of GA at 52 weeks in eyes without the CFI at-risk allele was slightly faster than the growth in eyes with the CFI at-risk allele (P ≥ .72). The authors of the current study found that in contrast to the faster growth rate reported in CFI-positive eyes from the MAHALO trial, the CFI positive eyes in the COMPLETE trial did not grow faster, and this analysis included 24 eyes that met the MAHALO eligibility criteria. Copyright 2015, SLACK Incorporated.Entities:
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Year: 2015 PMID： 26247461 DOI： 10.3928/23258160-20150730-15
Source DB: PubMed Journal: Ophthalmic Surg Lasers Imaging Retina ISSN： 2325-8160 Impact factor: 1.300