Literature DB >> 26243958

Detection and quantitative determination of diethylene glycol in ethyl alcohol using gamma- ray spectroscopy.

Chikkappa Udagani1, Thimmasandra Narayan Ramesh2.   

Abstract

Determination of the toxic diethylene glycol contamination in ethyl alcohol demands a rapid, accurate and reliable method. Diethylene glycol (DEG) ingestion, accidental or intentional, can lead to death. Clinical and analytical methods used to detect diethylene glycol in alcohol require several hours to days due to tedious instrument handling and measurements. Enzymatic assays face difficulty due to analytic problems. As an alternative method of data analysis, we have used γ-ray spectroscopic method to estimate the diethylene glycol contamination in alcohol by monitoring the variation in the linear and mass attenuation coefficients. This method is simple, robust, portable and can provide reliable and quantitative information about the ethyl alcohol adulterated with diethylene glycol which is of broader interest to society.

Entities:  

Keywords:  Adulteration; Detection; Diethylene glycol; Ethyl alcohol; Gamma-ray spectroscopy

Year:  2014        PMID: 26243958      PMCID: PMC4519459          DOI: 10.1007/s13197-014-1583-4

Source DB:  PubMed          Journal:  J Food Sci Technol        ISSN: 0022-1155            Impact factor:   2.701


  18 in total

1.  Rapid and specific quantification of ethylene glycol levels: adaptation of a commercial enzymatic assay to automated chemistry analyzers.

Authors:  Joetta M Juenke; Lindsay Hardy; Gwendolyn A McMillin; Gary L Horowitz
Journal:  Am J Clin Pathol       Date:  2011-08       Impact factor: 2.493

2.  Ethylene glycol poisoning: toxicokinetic and analytical factors affecting laboratory diagnosis.

Authors:  A F Eder; C M McGrath; Y G Dowdy; J E Tomaszewski; F M Rosenberg; R B Wilson; B A Wolf; L M Shaw
Journal:  Clin Chem       Date:  1998-01       Impact factor: 8.327

3.  Simultaneous determination of alcohols and ethylene glycol in serum by packed- or capillary-column gas chromatography.

Authors:  J F Livesey; S L Perkins; N E Tokessy; M J Maddock
Journal:  Clin Chem       Date:  1995-02       Impact factor: 8.327

4.  Simultaneous detection and quantitation of diethylene glycol, ethylene glycol, and the toxic alcohols in serum using capillary column gas chromatography.

Authors:  R H Williams; S M Shah; J A Maggiore; T B Erickson
Journal:  J Anal Toxicol       Date:  2000-10       Impact factor: 3.367

5.  Clinical parameters, postmortem analysis and estimation of lethal dose in victims of a massive intoxication with diethylene glycol.

Authors:  Luis A Ferrari; Leda Giannuzzi
Journal:  Forensic Sci Int       Date:  2005-10-04       Impact factor: 2.395

Review 6.  Current recommendations for treatment of severe toxic alcohol poisonings.

Authors:  Bruno Mégarbane; Stephen W Borron; Frédéric J Baud
Journal:  Intensive Care Med       Date:  2004-12-31       Impact factor: 17.440

7.  Fatal renal failure caused by diethylene glycol in paracetamol elixir: the Bangladesh epidemic.

Authors:  M Hanif; M R Mobarak; A Ronan; D Rahman; J J Donovan; M L Bennish
Journal:  BMJ       Date:  1995-07-08

8.  Diethylene glycol: widely used solvent presents serious poisoning potential.

Authors:  Jeanna M Marraffa; Michael G Holland; Christine M Stork; Christopher D Hoy; Michael J Hodgman
Journal:  J Emerg Med       Date:  2007-11-19       Impact factor: 1.484

Review 9.  Diethylene glycol poisoning.

Authors:  Leo J Schep; Robin J Slaughter; Wayne A Temple; D Michael G Beasley
Journal:  Clin Toxicol (Phila)       Date:  2009-07       Impact factor: 4.467

10.  Gas chromatographic determination of monoethylene glycol and diethylene glycol in chocolate packaged in regenerated cellulose film.

Authors:  L Castle; H R Cloke; J R Startin; J Gilbert
Journal:  J Assoc Off Anal Chem       Date:  1988 May-Jun
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