Farah Lone1, Ranee Thakar2, Andrzej P Wieczorek3, Abdul H Sultan1, Aleksandra Stankiewicz1. 1. Department of Obstetrics and Gynecology, Croydon University Hospital, 530 London Road, Croydon, UK, CR7 7YE. 2. Department of Obstetrics and Gynecology, Croydon University Hospital, 530 London Road, Croydon, UK, CR7 7YE. ranee.thakar@croydonhealth.nhs.uk. 3. Department of Pediatric Radiology, Children's Teaching Hospital, Lublin Medical University, Lublin, Poland.
Abstract
INTRODUCTION: Urethral vascularity is responsible for organ perfusion. It is also believed to contribute to maintaining the normal tension in the urethral mucosa and contributes to approximately one third of urethral closure pressure. We hypothesised that in women undergoing treatment for stress urinary incontinence (SUI), there is no change in blood flow intensity. METHODS: In this pilot study we recruited women attending the urogynaecology clinics between July and October 2009. Exclusion criteria included symptoms of pelvic organ prolapse or urinary tract infection. Colour Doppler ultrasound was performed at the level of the mid-urethra using a high-frequency (9-12 MHz) endovaginal ultrasonography (EVUS) focusing on the following vascular parameters: flow velocity (V), area of the vessels (A), intensity of perfusion (I), Tissue Pulsatility Index (TPI) and Tissue Resistance Index (TRI). Vascular assessments were repeated at 1 year. RESULTS: We examined 67 women with symptoms of SUI (17 women had surgery and 50 conservative management, i.e., pelvic floor muscle exercises). The mean (± SD) age in the conservative and surgical groups was 46 (±11) and 40 (±9) years respectively and median (range) parity was 2 (0-8) in both groups. Compared to baseline, no statistically significant differences were observed within each group (p > 0.05) or between the values of vascular parameters (V, A, I, TRI and TPI) at 1 year. There was also no difference in vascular parameters between the two groups. CONCLUSION: At 12 months there is no change in vascularity parameters in women who opt for conservative or surgical treatment of SUI.
INTRODUCTION: Urethral vascularity is responsible for organ perfusion. It is also believed to contribute to maintaining the normal tension in the urethral mucosa and contributes to approximately one third of urethral closure pressure. We hypothesised that in women undergoing treatment for stress urinary incontinence (SUI), there is no change in blood flow intensity. METHODS: In this pilot study we recruited women attending the urogynaecology clinics between July and October 2009. Exclusion criteria included symptoms of pelvic organ prolapse or urinary tract infection. Colour Doppler ultrasound was performed at the level of the mid-urethra using a high-frequency (9-12 MHz) endovaginal ultrasonography (EVUS) focusing on the following vascular parameters: flow velocity (V), area of the vessels (A), intensity of perfusion (I), Tissue Pulsatility Index (TPI) and Tissue Resistance Index (TRI). Vascular assessments were repeated at 1 year. RESULTS: We examined 67 women with symptoms of SUI (17 women had surgery and 50 conservative management, i.e., pelvic floor muscle exercises). The mean (± SD) age in the conservative and surgical groups was 46 (±11) and 40 (±9) years respectively and median (range) parity was 2 (0-8) in both groups. Compared to baseline, no statistically significant differences were observed within each group (p > 0.05) or between the values of vascular parameters (V, A, I, TRI and TPI) at 1 year. There was also no difference in vascular parameters between the two groups. CONCLUSION: At 12 months there is no change in vascularity parameters in women who opt for conservative or surgical treatment of SUI.
Authors: Giulio Aniello Santoro; Andrzej Paweł Wieczorek; Aleksandra Stankiewicz; Magdalena Maria Woźniak; Michał Bogusiewicz; Tomasz Rechberger Journal: Int Urogynecol J Pelvic Floor Dysfunct Date: 2009-06-17
Authors: Bernd Gagel; Marc Piroth; Michael Pinkawa; Patrick Reinartz; Michael Zimny; Hans J Kaiser; Sven Stanzel; Branka Asadpour; Cengiz Demirel; Kurt Hamacher; Heinz H Coenen; Thomas Scholbach; Payam Maneschi; Ercole DiMartino; Michael J Eble Journal: BMC Cancer Date: 2007-06-28 Impact factor: 4.430