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Literature DB >> 26240104

Ulcerated tophaceous gout.

Michelle Gita Filanovsky¹, Kumar Sukhdeo², Megan Cunnane McNamara³.

Abstract

Gout is an inflammatory arthritis characterised by hyperuricemia, which, if poorly controlled, can lead to the development of tophi. We report the case of a 60-year-old Caucasian man with poorly controlled polyarticular tophaceous gout with multiple comorbidities (including renal failure) who presented with tophaceous ulcers of the upper extremity. These ulcers caused extreme pain, requiring chronic opiate medications, and were associated with decreased sensation and reduced ability to move the extremity. His hospital course was complicated by acute kidney injury, haemolytic anaemia and Clostridium difficile infection. He required 1 month of antibiotics and intensive wound care for his ulcers. This case highlights the diagnosis, natural history and management of an unusual complication of hyperuricemia. 2015 BMJ Publishing Group Ltd.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 2015 PMID： 26240104 PMCID： PMC4533602 DOI： 10.1136/bcr-2015-210707

Source DB: PubMed Journal: BMJ Case Rep ISSN： 1757-790X

22 in total

1. Multicentre prospective observational study on professional wound care using honey (Medihoney™).

Authors: Bahram Biglari; Arash Moghaddam; Kai Santos; Gisela Blaser; Axel Büchler; Gisela Jansen; Alfred Längler; Norbert Graf; Ursula Weiler; Verena Licht; Anke Strölin; Brigitta Keck; Volker Lauf; Udo Bode; Tyler Swing; Ralph Hanano; Nicolas T Schwarz; Arne Simon
Journal: Int Wound J Date: 2012-04-11 Impact factor: 3.315

Review 2. Clinical practice. Gout.

Authors: Tuhina Neogi
Journal: N Engl J Med Date: 2011-02-03 Impact factor: 91.245

3. 2012 American College of Rheumatology guidelines for management of gout. Part 1: systematic nonpharmacologic and pharmacologic therapeutic approaches to hyperuricemia.

Authors: Dinesh Khanna; John D Fitzgerald; Puja P Khanna; Sangmee Bae; Manjit K Singh; Tuhina Neogi; Michael H Pillinger; Joan Merill; Susan Lee; Shraddha Prakash; Marian Kaldas; Maneesh Gogia; Fernando Perez-Ruiz; Will Taylor; Frédéric Lioté; Hyon Choi; Jasvinder A Singh; Nicola Dalbeth; Sanford Kaplan; Vandana Niyyar; Danielle Jones; Steven A Yarows; Blake Roessler; Gail Kerr; Charles King; Gerald Levy; Daniel E Furst; N Lawrence Edwards; Brian Mandell; H Ralph Schumacher; Mark Robbins; Neil Wenger; Robert Terkeltaub
Journal: Arthritis Care Res (Hoboken) Date: 2012-10 Impact factor: 4.794

4. Subconjunctival urate crystals: a case report.

Authors: Prafulla Sarma; Dipankar Das; Panna Deka; Akshay C Deka
Journal: Cornea Date: 2010-07 Impact factor: 2.651

Review 5. Uric acid and chronic kidney disease: which is chasing which?

Authors: Richard J Johnson; Takahiko Nakagawa; Diana Jalal; Laura Gabriela Sánchez-Lozada; Duk-Hee Kang; Eberhard Ritz
Journal: Nephrol Dial Transplant Date: 2013-03-29 Impact factor: 5.992

6. Ulcerated tophaceous gout.

Authors: Girish K Patel; Wendy L Davies; Patricia P Price; Keith G Harding
Journal: Int Wound J Date: 2010-10 Impact factor: 3.315

7. Tophaceous gout and high level of hyperuricaemia are both associated with increased risk of mortality in patients with gout.

Authors: Fernando Perez-Ruiz; Lorea Martínez-Indart; Loreto Carmona; Ana Maria Herrero-Beites; Jose Ignacio Pijoan; Eswar Krishnan
Journal: Ann Rheum Dis Date: 2013-01-12 Impact factor: 19.103

Ulcerated tophaceous gout.

1. Multicentre prospective observational study on professional wound care using honey (Medihoney™).

Review 2. Clinical practice. Gout.

3. 2012 American College of Rheumatology guidelines for management of gout. Part 1: systematic nonpharmacologic and pharmacologic therapeutic approaches to hyperuricemia.

4. Subconjunctival urate crystals: a case report.

Review 5. Uric acid and chronic kidney disease: which is chasing which?

6. Ulcerated tophaceous gout.

7. Tophaceous gout and high level of hyperuricaemia are both associated with increased risk of mortality in patients with gout.

8. A survey of indications, results and complications of surgery for tophaceous gout.

9. Surgical treatment of the chronic tophaceous deformity in upper extremities - the shaving technique.

10. Citric acid treatment of chronic nonhealing ulcerated tophaceous gout with bursitis.

1. Ulcerated tophaceous gout.

2. Asymptomatic Papules and Subcutaneous Nodules as First Sign of Gout.

3. Chronic Tophaceous Gout Presenting as Bilateral Knee Masses in an Adult Patient: A Case Report.