Literature DB >> 22494449

Multicentre prospective observational study on professional wound care using honey (Medihoney™).

Bahram Biglari1, Arash Moghaddam, Kai Santos, Gisela Blaser, Axel Büchler, Gisela Jansen, Alfred Längler, Norbert Graf, Ursula Weiler, Verena Licht, Anke Strölin, Brigitta Keck, Volker Lauf, Udo Bode, Tyler Swing, Ralph Hanano, Nicolas T Schwarz, Arne Simon.   

Abstract

In recent years, the treatment of wounds with honey has received an increasing amount of attention from healthcare professionals in Germany and Austria. We conducted a prospective observational multicentre study using Medihoney™ dressings in 10 hospitals - nine in Germany and one in Austria. Wound-associated parameters were monitored systematically at least three times in all patients. Data derived from the treatment of 121 wounds of various aetiologies over a period of 2 years were analysed. Almost half of the patients were younger than 18 years old, and 32% of the study population was oncology patients. Overall, wound size decreased significantly during the study period and many wounds healed after relatively short time periods. Similarly, perceived pain levels decreased significantly, and the wounds showed noticeably less slough/necrosis. In general, our findings show honey to be an effective and feasible treatment option for professional wound care. In addition, our study showed a relationship between pain and slough/necrosis at the time of recruitment and during wound healing. Future comparative trials are still needed to evaluate the extent to which the positive observations made in this and other studies can definitely be attributed to the effects of honey in wound care.
© 2012 The Authors. International Wound Journal © 2012 John Wiley & Sons Ltd and Medicalhelplines.com Inc.

Entities:  

Mesh:

Year:  2012        PMID: 22494449      PMCID: PMC7950896          DOI: 10.1111/j.1742-481X.2012.00970.x

Source DB:  PubMed          Journal:  Int Wound J        ISSN: 1742-4801            Impact factor:   3.315


  34 in total

Review 1.  Potential of honey in the treatment of wounds and burns.

Authors:  P C Molan
Journal:  Am J Clin Dermatol       Date:  2001       Impact factor: 7.403

2.  Bactericidal activity of different honeys against pathogenic bacteria.

Authors:  Patricia E Lusby; Alexandra L Coombes; Jenny M Wilkinson
Journal:  Arch Med Res       Date:  2005 Sep-Oct       Impact factor: 2.235

Review 3.  The evidence supporting the use of honey as a wound dressing.

Authors:  P C Molan
Journal:  Int J Low Extrem Wounds       Date:  2006-03       Impact factor: 2.057

Review 4.  A systematic review of honey uses and its potential value within oncology care.

Authors:  Joy Bardy; Nicholas J Slevin; Kathleen L Mais; Alexander Molassiotis
Journal:  J Clin Nurs       Date:  2008-10       Impact factor: 3.036

5.  The unusual antibacterial activity of medical-grade Leptospermum honey: antibacterial spectrum, resistance and transcriptome analysis.

Authors:  S E Blair; N N Cokcetin; E J Harry; D A Carter
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2009-06-10       Impact factor: 3.267

Review 6.  Understanding wound bed preparation and wound debridement.

Authors:  Karen Ousey; Caroline McIntosh
Journal:  Br J Community Nurs       Date:  2010-03

7.  The honeypot study protocol: a randomized controlled trial of exit-site application of medihoney antibacterial wound gel for the prevention of catheter-associated infections in peritoneal dialysis patients.

Authors:  David W Johnson; Carolyn Clark; Nicole M Isbel; Carmel M Hawley; Elaine Beller; Alan Cass; Janak de Zoysa; Steven McTaggart; Geoffrey Playford; Brenda Rosser; Charles Thompson; Paul Snelling
Journal:  Perit Dial Int       Date:  2009 May-Jun       Impact factor: 1.756

Review 8.  Minimising wound-related pain at dressing change: evidence-informed practice.

Authors:  Kevin Y Woo; Keith Harding; Patricia Price; Gary Sibbald
Journal:  Int Wound J       Date:  2008-06       Impact factor: 3.315

9.  Honey stimulates inflammatory cytokine production from monocytes.

Authors:  A J Tonks; R A Cooper; K P Jones; S Blair; J Parton; A Tonks
Journal:  Cytokine       Date:  2003-03-07       Impact factor: 3.861

10.  Antibacterial activity of honey against community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA).

Authors:  Yasunori Maeda; Anne Loughrey; J A Philip Earle; B Cherie Millar; Juluri R Rao; Angela Kearns; Ogie McConville; Colin E Goldsmith; Paul J Rooney; James S G Dooley; Colm J Lowery; William J Snelling; Ann McMahon; David McDowell; John E Moore
Journal:  Complement Ther Clin Pract       Date:  2008-03-04       Impact factor: 2.446

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  7 in total

Review 1.  Dressings and Products in Pediatric Wound Care.

Authors:  Alice King; Judith J Stellar; Anne Blevins; Kara Noelle Shah
Journal:  Adv Wound Care (New Rochelle)       Date:  2014-04-01       Impact factor: 4.730

Review 2.  Up-to-date use of honey for burns treatment.

Authors:  A Zbuchea
Journal:  Ann Burns Fire Disasters       Date:  2014-03-31

3.  A Comparison of the Effects of Topical Prolavacid Solution (a Polyhexamethylene Biguanide-Based Wound Cleanser) and Medihoney Ointment in a Rat Model of Cutaneous Wound.

Authors:  Shahram Paydar; Bijan Ziaeian; Amirreza Dehghanian; Mohsen Heidarpour; Roshanak Alavi Moghadam; Behnam Dalfardi; Abbas Hallaj Karladani
Journal:  Adv Wound Care (New Rochelle)       Date:  2017-12-01       Impact factor: 4.730

4.  Analgesic and anti-inflammatory effects of honey: the involvement of autonomic receptors.

Authors:  Bamidele Victor Owoyele; Rasheed Olajiire Oladejo; Kayode Ajomale; Rasheedat Omotayo Ahmed; Abdulrasheed Mustapha
Journal:  Metab Brain Dis       Date:  2013-12-10       Impact factor: 3.584

5.  Ulcerated tophaceous gout.

Authors:  Michelle Gita Filanovsky; Kumar Sukhdeo; Megan Cunnane McNamara
Journal:  BMJ Case Rep       Date:  2015-08-03

6.  Evaluation of the effects of honey on acute-phase deep burn wounds.

Authors:  Yukari Nakajima; Kanae Mukai; Emi Komatsu; Terumi Iuchi; Yukie Kitayama; Junko Sugama; Toshio Nakatani
Journal:  Evid Based Complement Alternat Med       Date:  2013-11-17       Impact factor: 2.629

Review 7.  Therapeutic Manuka Honey: No Longer So Alternative.

Authors:  Dee A Carter; Shona E Blair; Nural N Cokcetin; Daniel Bouzo; Peter Brooks; Ralf Schothauer; Elizabeth J Harry
Journal:  Front Microbiol       Date:  2016-04-20       Impact factor: 5.640

  7 in total

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