Literature DB >> 26238315

Clinical characteristics and surgical outcome of thoracic myelopathy caused by ossification of the ligamentum flavum: a retrospective analysis of 85 cases.

Z Li1,2, D Ren1, Y Zhao1, S Hou1, L Li1, S Yu3, T Hou3.   

Abstract

STUDY
DESIGN: A retrospective comparative study.
OBJECTIVES: To describe the clinical features and radiological findings, to assess the safety and effectiveness of posterior decompressive laminectomy and resection of the ossification of the ligamentum flavum (OLF), and to determine which presurgical and surgical variables were most closely related to postsurgical prognosis of thoracic myelopathy (TM) caused by OLF in China.
METHODS: Eighty-five patients with the diagnosis of TM caused by OLF received surgical treatment from July 1998 to May 2012. Clinical data were collected from medical and operative records. Correlations between the surgical outcome and various factors were also analyzed.
RESULTS: All cases were followed up for a mean of 49.2 months (range, 24-190 months) postoperatively. The mean Japanese Orthopaedic Association score was 3.8 points preoperatively and 8.2 points at the final follow-up, yielding a mean recovery rate of 63.0%. Postoperative complications included transient neurological deficits (9 cases), persistent neurological deficits (4 cases), dural tears (17 cases), cerebrospinal fluid leakage (9 cases), wound dehiscence (2 cases) and wound infection (3 cases). The OLF level (middle thoracic), preoperative duration of symptoms, intramedullary signal change on T2WI and preoperative severity of myelopathy were important predictors of surgical outcome.
CONCLUSIONS: Biomechanical and anatomical factors may have a key role in thoracic OLF progression. Posterior decompressive laminectomy and resection of the OLF can be considered an effective, reliable and safe alternative procedure. The OLF level, preoperative duration of symptoms, intramedullary signal change on T2WI and preoperative severity of myelopathy were confirmed and significantly correlated with the surgical outcome.

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Mesh:

Year:  2015        PMID: 26238315     DOI: 10.1038/sc.2015.139

Source DB:  PubMed          Journal:  Spinal Cord        ISSN: 1362-4393            Impact factor:   2.772


  77 in total

1.  Total decompression of the spinal cord for combined ossification of posterior longitudinal ligament and yellow ligament in the thoracic spine.

Authors:  K Tomita
Journal:  Arch Orthop Trauma Surg       Date:  1990       Impact factor: 3.067

2.  Diagnosis and treatment of ossification of the ligamentum flavum associated with dural ossification: clinical article.

Authors:  Xin-Zhi Sun; Zhong-Qiang Chen; Qiang Qi; Zhao-Qing Guo; Chui-Guo Sun; Wei-Shi Li; Yan Zeng
Journal:  J Neurosurg Spine       Date:  2011-07-01

3.  Predictive factors for a poor surgical outcome with thoracic ossification of the ligamentum flavum by multivariate analysis: a multicenter study.

Authors:  Kei Ando; Shiro Imagama; Zenya Ito; Kenichi Hirano; Akio Muramoto; Fumihiko Kato; Yasutsugu Yukawa; Noriaki Kawakami; Koji Sato; Yuji Matsubara; Tokumi Kanemura; Yukihiro Matsuyama; Naoki Ishiguro
Journal:  Spine (Phila Pa 1976)       Date:  2013-05-20       Impact factor: 3.468

4.  Ossification of the ligamentum flavum as a result of fluorosis causing myelopathy: report of two cases.

Authors:  Natarajan Muthukumar
Journal:  Neurosurgery       Date:  2005-03       Impact factor: 4.654

5.  Circumspinal decompression for thoracic myelopathy due to combined ossification of the posterior longitudinal ligament and ligamentum flavum.

Authors:  K Tomita; N Kawahara; H Baba; Y Kikuchi; H Nishimura
Journal:  Spine (Phila Pa 1976)       Date:  1990-11       Impact factor: 3.468

6.  Ossification of the ligamenta flava with severe myelopathy in a black patient. A case report.

Authors:  H Pascal-Mousselard; D Smadja; P Cabre; M Raynaud; Y Catonne
Journal:  Spine (Phila Pa 1976)       Date:  1998-07-15       Impact factor: 3.468

7.  Thoracic myelopathy due to ossification of the yellow ligament in young baseball pitchers.

Authors:  Shuichi Kaneyama; Minoru Doita; Kotaro Nishida; Takatoshi Shimomura; Koichiro Maeno; Yuichi Tamura; Masahiro Kurosaka; Kazuo Yonenobu
Journal:  J Spinal Disord Tech       Date:  2008-02

8.  Thoracic myelopathy caused by ossification of the ligamentum flavum. Clinicopathologic study and surgical treatment.

Authors:  K Okada; S Oka; K Tohge; K Ono; K Yonenobu; T Hosoya
Journal:  Spine (Phila Pa 1976)       Date:  1991-03       Impact factor: 3.468

9.  Prevalence of ossification of posterior longitudinal ligament in patients with ankylosing spondylitis.

Authors:  Tae-Jong Kim; Tae-Hwan Kim; Jae-Bum Jun; Kyung-Bin Joo; Wan-Sik Uhm
Journal:  J Rheumatol       Date:  2007-11-15       Impact factor: 4.666

10.  Ossification process involving the human thoracic ligamentum flavum: role of transcription factors.

Authors:  Kenzo Uchida; Takafumi Yayama; Hong-Xin Cai; Hideaki Nakajima; Daisuke Sugita; Alexander Rodríguez Guerrero; Shigeru Kobayashi; Ai Yoshida; Ke-Bing Chen; Hisatoshi Baba
Journal:  Arthritis Res Ther       Date:  2011-09-13       Impact factor: 5.156

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  20 in total

1.  The bridge crane technique for the treatment of the severe thoracic ossification of the ligamentum flavum with myelopathy.

Authors:  Jingchuan Sun; Kaiqiang Sun; Jiangang Shi; Ximing Xu; Yuan Wang; Qingjie Kong
Journal:  Eur Spine J       Date:  2018-06-29       Impact factor: 3.134

Review 2.  A systematic review of complications in thoracic spine surgery for ossification of ligamentum flavum.

Authors:  Xiaofei Hou; Zhongqiang Chen; Chuiguo Sun; Guangwu Zhang; Sijun Wu; Zheng Liu
Journal:  Spinal Cord       Date:  2017-12-28       Impact factor: 2.772

3.  Percutaneous full endoscopic posterior decompression of thoracic myelopathy caused by ossification of the ligamentum flavum.

Authors:  Bo An; Xing-Chen Li; Cheng-Pei Zhou; Bi-Sheng Wang; Hao-Ran Gao; Hai-Jun Ma; Yi He; Hong-Gang Zhou; He-Jun Yang; Ji-Xian Qian
Journal:  Eur Spine J       Date:  2019-01-17       Impact factor: 3.134

Review 4.  Outcomes and Complications Following Laminectomy Alone for Thoracic Myelopathy due to Ossified Ligamentum Flavum: A Systematic Review and Meta-Analysis.

Authors:  Nebiyu S Osman; Zoe B Cheung; Awais K Hussain; Kevin Phan; Varun Arvind; Khushdeep S Vig; Luilly Vargas; Jun S Kim; Samuel Kang-Wook Cho
Journal:  Spine (Phila Pa 1976)       Date:  2018-07-15       Impact factor: 3.241

5.  Minimally invasive surgery for resection of ossification of the ligamentum flavum in the thoracic spine.

Authors:  Wei Zhao; Chaoxiong Shen; Ranze Cai; Jianfeng Wu; Yuandong Zhuang; Zhaowen Cai; Rui Wang; Chunmei Chen
Journal:  Wideochir Inne Tech Maloinwazyjne       Date:  2017-03-13       Impact factor: 1.195

6.  Surgical Results of Patients with Myelopathy due to Ossification of the Ligamentum Flavum with Ossification of the Posterior Longitudinal Ligament or a Vertebral Fracture at the Same Level of the Thoracic Spine: A Retrospective Comparative Study.

Authors:  Yuji Kasukawa; Naohisa Miyakoshi; Michio Hongo; Yoshinori Ishikawa; Daisuke Kudo; Ryota Kimura; Yuichi Ono; Jumpei Iida; Chiaki Sato; Yoichi Shimada
Journal:  Asian Spine J       Date:  2019-06-03

7.  The incidence and risk factors of postoperative neurological deterioration after posterior decompression with or without instrumented fusion for thoracic myelopathy.

Authors:  Hui Wang; Lei Ma; Rui Xue; Dalong Yang; Tao Wang; Yanhong Wang; Sidong Yang; Wenyuan Ding
Journal:  Medicine (Baltimore)       Date:  2016-12       Impact factor: 1.817

8.  Clinical Outcomes and Prognostic Factors in Patients With Myelopathy Caused by Thoracic Ossification of the Ligamentum Flavum.

Authors:  Jae-Kwang Kim; Hyun-Seung Ryu; Bong Ju Moon; Jung-Kil Lee
Journal:  Neurospine       Date:  2018-09-07

9.  Muscular Activity Modulation During Post-operative Walking With Hybrid Assistive Limb (HAL) in a Patient With Thoracic Myelopathy Due to Ossification of Posterior Longitudinal Ligament: A Case Report.

Authors:  Hideki Kadone; Shigeki Kubota; Tetsuya Abe; Hiroshi Noguchi; Kousei Miura; Masao Koda; Yukiyo Shimizu; Yasushi Hada; Yoshiyuki Sankai; Kenji Suzuki; Masashi Yamazaki
Journal:  Front Neurol       Date:  2020-03-31       Impact factor: 4.003

10.  Thoracic full-endoscopic unilateral laminotomy with bilateral decompression for treating ossification of the ligamentum flavum with myelopathy.

Authors:  Yong-Peng Lin; Rui Lin; Song Chen; Si-Yuan Rao; Shuai Zhao; Tao Wen; Hong-Shen Wang; Wei-Xiong Hu; Bing-Xin Liu; Xin-Yi Li; Yong-Jin Li; Bo-Lai Chen
Journal:  Ann Transl Med       Date:  2021-06
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