Literature DB >> 23474599

Predictive factors for a poor surgical outcome with thoracic ossification of the ligamentum flavum by multivariate analysis: a multicenter study.

Kei Ando1, Shiro Imagama, Zenya Ito, Kenichi Hirano, Akio Muramoto, Fumihiko Kato, Yasutsugu Yukawa, Noriaki Kawakami, Koji Sato, Yuji Matsubara, Tokumi Kanemura, Yukihiro Matsuyama, Naoki Ishiguro.   

Abstract

STUDY
DESIGN: Retrospective multi-institutional study.
OBJECTIVE: The purpose of this study was to describe the surgical outcomes in patients with ossification of the ligamentum flavum (OLF) and determine the influence of an ossified anterior longitudinal ligament (OALL) on the clinical features and surgical outcomes in thoracic OLF. SUMMARY OF BACKGROUND DATA: Detailed analyses of surgical outcomes of thoracic OLF have been difficult because of rarity of this disease.
METHODS: We identified 96 patients (77 males and 19 females with a mean age at surgery of 63.4 ± 10.3 yr) who underwent surgery for thoracic OLF and investigated their preoperative symptoms, severity of symptoms and myelopathy, disease duration, magnetic resonance imaging and computed tomographic findings, surgical procedure, intraoperative findings, and postoperative recoveries. The presence of OALL found at or near the most severely affected OLF level on sagittal computed tomographic images was classified into 1 of the following 4 types: (1) "no discernible type" (type N); (2) "one-sided type" (type O); (3) "discontinuous type" (type D); and (4) "continuous type" (type C). Multivariate logistic regression analysis was used to compute odds ratios and 95% confidence intervals to identify the risk factors associated with surgical outcomes.
RESULTS: The mean Japanese Orthopaedic Association score was 5.6 points preoperatively and 7.8 points 2 years postoperatively, yielding a mean recovery rate of 44.6%. Disease duration, presence of ossified dura mater, and type D OALL were the important factors for predicting surgical outcomes.
CONCLUSION: After evaluating surgical outcomes on the largest sample size of OLF surgical procedures thus far, our results show that disease duration, ossification of the dura mater, and the presence of type D OALL were risk factors related to surgical outcomes. LEVEL OF EVIDENCE: 3.

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Year:  2013        PMID: 23474599     DOI: 10.1097/BRS.0b013e31828ff736

Source DB:  PubMed          Journal:  Spine (Phila Pa 1976)        ISSN: 0362-2436            Impact factor:   3.468


  20 in total

1.  Percutaneous full endoscopic posterior decompression of thoracic myelopathy caused by ossification of the ligamentum flavum.

Authors:  Bo An; Xing-Chen Li; Cheng-Pei Zhou; Bi-Sheng Wang; Hao-Ran Gao; Hai-Jun Ma; Yi He; Hong-Gang Zhou; He-Jun Yang; Ji-Xian Qian
Journal:  Eur Spine J       Date:  2019-01-17       Impact factor: 3.134

2.  Progressive relapse of ligamentum flavum ossification following decompressive surgery.

Authors:  Kei Ando; Shiro Imagama; Zenya Ito; Kazuyoshi Kobayashi; Junichi Ukai; Akio Muramoto; Ryuichi Shinjo; Tomohiro Matsumoto; Hiroaki Nakashima; Naoki Ishiguro
Journal:  Asian Spine J       Date:  2014-12-17

3.  Thoracic ossification of the ligamentum flavum causing acute myelopathy in a patient with cervical ossification of the posterior longitudinal ligament: illustrative case.

Authors:  Kishan S Shah; Christopher M Uchiyama
Journal:  J Neurosurg Case Lessons       Date:  2021-09-06

4.  Microendoscopic posterior decompression for the treatment of thoracic myelopathy caused by ossification of the ligamentum flavum: a technical report.

Authors:  Satoshi Baba; Yasushi Oshima; Tomoyuki Iwahori; Yuichi Takano; Hirohiko Inanami; Hisashi Koga
Journal:  Eur Spine J       Date:  2015-07-30       Impact factor: 3.134

5.  Clinical characteristics and surgical outcome of thoracic myelopathy caused by ossification of the ligamentum flavum: a retrospective analysis of 85 cases.

Authors:  Z Li; D Ren; Y Zhao; S Hou; L Li; S Yu; T Hou
Journal:  Spinal Cord       Date:  2015-08-04       Impact factor: 2.772

6.  Predictors of surgical outcome in thoracic ossification of the ligamentum flavum: focusing on the quantitative signal intensity.

Authors:  JingTao Zhang; LinFeng Wang; Jie Li; Peng Yang; Yong Shen
Journal:  Sci Rep       Date:  2016-03-10       Impact factor: 4.379

7.  Imaging grading system for the diagnosis of dural ossification based on 102 segments of TOLF CT bone-window data.

Authors:  Sheng-Yuan Zhou; Bo Yuan; Xiong-Sheng Chen; Xue-Bin Li; Wei Zhu; Lian-Shun Jia
Journal:  Sci Rep       Date:  2017-06-07       Impact factor: 4.379

8.  Ossification of the Ligamentum Flavum in a Nineteenth-Century Skeletal Population Sample from Ireland: Using Bioarchaeology to Reveal a Neglected Spine Pathology.

Authors:  Jonny Geber; Niels Hammer
Journal:  Sci Rep       Date:  2018-06-18       Impact factor: 4.379

9.  Multilevel thoracic ossification of ligamentum flavum coexisted with/without lumbar spinal stenosis: staged surgical strategy and clinical outcomes.

Authors:  Wen-jing Li; Shi-gong Guo; Zhi-jian Sun; Yu Zhao
Journal:  BMC Musculoskelet Disord       Date:  2015-08-19       Impact factor: 2.362

10.  Spinal Cord Kinking in Thoracic Myelopathy Caused by Ossification of the Ligamentum Flavum.

Authors:  Ting Wang; Min Pan; Chu-Qiang Yin; Xiu-Jun Zheng; Ya-Nan Cong; De-Chun Wang; Shu-Zhong Li
Journal:  Chin Med J (Engl)       Date:  2015-10-05       Impact factor: 2.628

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