Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 DNA damage in synchronized HeLa cells irradiated with ultraviolet.

Literature DB >> 262382

DNA damage in synchronized HeLa cells irradiated with ultraviolet.

Abstract

The lethal effect of UV radiation of HeLa cells is least in mitosis and greatest in late G1-early S. Photochemical damage to HeLa DNA, as measured by thymine-containing dimer formation and by alkaline sucrose sedimentation, also increases from mitosis towards early S phase. Computer simulations of UV absorption by an idealized HeLa cell at different stages of the cell cycle indicate that changes in damage could be due solely to changes in chromatin geometry. But survival is not exclusively a function of damage.

Entities: Chemical

Mesh：

Year: 1979 PMID： 262382 PMCID： PMC1328452 DOI： 10.1016/S0006-3495(79)85282-0

Source DB: PubMed Journal: Biophys J ISSN： 0006-3495 Impact factor: 4.033

65 in total

1. Light scattering from nucleated biological cells.

Authors: R A Meyer; A Brunsting
Journal: Biophys J Date: 1975-03 Impact factor: 4.033

2. Different ultraviolet DNA endonuclease activity in human cells.

Authors: N J Duker; G W Teebor
Journal: Nature Date: 1975-05-01 Impact factor: 49.962

3. Detection by electron microscopy of photo-induced denaturation in lambda DNA.

Authors: R S Stafford; D P Allison; R O Rahn
Journal: Nucleic Acids Res Date: 1975-02 Impact factor: 16.971

4. Chromatin changes during the cell cycle of HeHa cells.

Authors: C Nicolini; K Ajiro; T W Borun; R Baserga
Journal: J Biol Chem Date: 1975-05-10 Impact factor: 5.157

5. Tritosol: a new scintillation cocktail based on Triton X-100.

Authors: U Fricke
Journal: Anal Biochem Date: 1975-02 Impact factor: 3.365

6. Cell-cycle-specific changes in chromatin organization.

Authors: C E Hildebrand; R A Tobey
Journal: Biochem Biophys Res Commun Date: 1975-03-03 Impact factor: 3.575

7. Repair of ultraviolet-damaged DNA in Micrococcus lysodeikticus. II. In vivo investigation on endonuclease activity specific for ultraviolet-irradiated DNA.

Authors: S Okubo; H Nakayama; Y Takagi
Journal: Biochim Biophys Acta Date: 1971-01-01

8. Sensitivity of synchronized Chinese hamster cells to ultraviolet light.

Authors: A Han; W K Sinclair
Journal: Biophys J Date: 1969-09 Impact factor: 4.033

9. Radiosensitive structure of metaphase and interphase hamster cells as studies by low-voltage electron beam irradiation.

Authors: A Zermeno; A Cole
Journal: Radiat Res Date: 1969-09 Impact factor: 2.841

DNA damage in synchronized HeLa cells irradiated with ultraviolet.

1. Light scattering from nucleated biological cells.

2. Different ultraviolet DNA endonuclease activity in human cells.

3. Detection by electron microscopy of photo-induced denaturation in lambda DNA.

4. Chromatin changes during the cell cycle of HeHa cells.

5. Tritosol: a new scintillation cocktail based on Triton X-100.

6. Cell-cycle-specific changes in chromatin organization.

7. Repair of ultraviolet-damaged DNA in Micrococcus lysodeikticus. II. In vivo investigation on endonuclease activity specific for ultraviolet-irradiated DNA.

8. Sensitivity of synchronized Chinese hamster cells to ultraviolet light.

9. Radiosensitive structure of metaphase and interphase hamster cells as studies by low-voltage electron beam irradiation.

10. Mitotic synchrony in mammalian cells treated with nitrous oxide at high pressure.

1. UV-C irradiation delays mitotic progression by recruiting Mps1 to kinetochores.

2. Side effects in excimer corneal surgery. DNA damage as a result of 193 nm excimer laser radiation.

3. Turn-on DNA damage sensors for the direct detection of 8-oxoguanine and photoproducts in native DNA.

4. Effects of DNA replication inhibitors on UV excision repair in synchronised human cells.

5. Gene-specific and strand-specific DNA repair in the G1 and G2 phases of the cell cycle.

6. Novobiocin; an inhibitor of the repair of UV-induced but not X-ray-induced damage in mammalian cells.

7. Comet-FISH with strand-specific probes reveals transcription-coupled repair of 8-oxoGuanine in human cells.