Literature DB >> 26234959

Does iodinated contrast medium amplify DNA damage during exposure to radiation.

Peter Riley1.   

Abstract

There is a recognized increased risk of cancer following exposure of humans to ionizing radiation; this is felt to be most likely due to damage to DNA strands during exposure. Damage to DNA strands can be demonstrated microscopically following exposure to X-rays, and new evidence is emerging that this effect may be compounded by administration of iodinated contrast agents.

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Year:  2015        PMID: 26234959      PMCID: PMC4743464          DOI: 10.1259/bjr.20150474

Source DB:  PubMed          Journal:  Br J Radiol        ISSN: 0007-1285            Impact factor:   3.039


  12 in total

1.  UNSCEAR report 2000: sources and effects of ionizing radiation. United Nations Scientific Comittee on the Effects of Atomic Radiation.

Authors:  M Charles
Journal:  J Radiol Prot       Date:  2001-03       Impact factor: 1.394

2.  IN VIVO EFFECTS OF DIAGNOSTIC X-IRRADIATION ON HUMAN CHROMOSOMES.

Authors:  A D BLOOM; J H TJIO
Journal:  N Engl J Med       Date:  1964-06-18       Impact factor: 91.245

3.  Risk of cancer from diagnostic X-rays: estimates for the UK and 14 other countries.

Authors:  Amy Berrington de González; Sarah Darby
Journal:  Lancet       Date:  2004-01-31       Impact factor: 79.321

4.  In vivo formation and repair of DNA double-strand breaks after computed tomography examinations.

Authors:  Markus Löbrich; Nicole Rief; Martin Kühne; Martina Heckmann; Jochen Fleckenstein; Christian Rübe; Michael Uder
Journal:  Proc Natl Acad Sci U S A       Date:  2005-06-13       Impact factor: 11.205

5.  Long-term radiation-related health effects in a unique human population: lessons learned from the atomic bomb survivors of Hiroshima and Nagasaki.

Authors:  Evan B Douple; Kiyohiko Mabuchi; Harry M Cullings; Dale L Preston; Kazunori Kodama; Yukiko Shimizu; Saeko Fujiwara; Roy E Shore
Journal:  Disaster Med Public Health Prep       Date:  2011-03       Impact factor: 1.385

Review 6.  The cytotoxicity of iodinated radiocontrast agents on renal cells in vitro.

Authors:  Christlieb Haller; Istvan Hizoh
Journal:  Invest Radiol       Date:  2004-03       Impact factor: 6.016

7.  Contrast medium-enhanced radiation damage caused by CT examinations.

Authors:  Saskia Grudzenski; Michael A Kuefner; Martina B Heckmann; Michael Uder; Markus Löbrich
Journal:  Radiology       Date:  2009-09-29       Impact factor: 11.105

8.  DNA double-strand breaks after percutaneous transluminal angioplasty.

Authors:  Dominik Geisel; Johannes T Heverhagen; Marc Kalinowski; Hans-Joachim Wagner
Journal:  Radiology       Date:  2008-09       Impact factor: 11.105

9.  Radiation exposure from CT scans in childhood and subsequent risk of leukaemia and brain tumours: a retrospective cohort study.

Authors:  Mark S Pearce; Jane A Salotti; Mark P Little; Kieran McHugh; Choonsik Lee; Kwang Pyo Kim; Nicola L Howe; Cecile M Ronckers; Preetha Rajaraman; Alan W Sir Craft; Louise Parker; Amy Berrington de González
Journal:  Lancet       Date:  2012-06-07       Impact factor: 79.321

10.  Megabase chromatin domains involved in DNA double-strand breaks in vivo.

Authors:  E P Rogakou; C Boon; C Redon; W M Bonner
Journal:  J Cell Biol       Date:  1999-09-06       Impact factor: 10.539

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  1 in total

Review 1.  Enhanced radiation dose and DNA damage associated with iodinated contrast media in diagnostic X-ray imaging.

Authors:  Richard Harbron; Elizabeth A Ainsbury; Simon D Bouffler; Rick J Tanner; Jonathan S Eakins; Mark S Pearce
Journal:  Br J Radiol       Date:  2017-08-22       Impact factor: 3.039

  1 in total

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