L Pierot1, J Klisch2, T Liebig3, J-Y Gauvrit4, M Leonardi5, N P Nuzzi6, F Di Paola7, V Sychra2, B Mine8, B Lubicz8. 1. From the Department of Neuroradiology (L.P.), Hôpital Maison-Blanche, Université Reims-Champagne-Ardenne, Reims, France lpierot@gmail.com. 2. Department of Diagnostic and Interventional Radiology and Neuroradiology (J.K., V.S.), Helios General Hospital, Erfurt, Germany. 3. Department of Neuroradiology (T.L.), Universitätsklinikum Köln, Cologne, Germany. 4. Department of Neuroradiology (J.-Y.G.), CHU Rennes, Rennes, France. 5. Department of Neuroradiology (M.L.), Ospedale Bellaria, Bologna University, Bologna, Italy. 6. Department of Neuroradiology (N.P.N.), Ospedale Galliera, Genova, Italy. 7. Department of Neuroradiology (F.D.P.), Ospedale Santa Maria, Treviso, Italy. 8. Department of Neuroradiology (B.M., B.L.), Erasme University Hospital, Brussels, Belgium.
Abstract
BACKGROUND AND PURPOSE: Flow disruption with the WEB-DL device has been used safely for the treatment of wide-neck bifurcation aneurysms. The stability of aneurysm occlusion after this treatment was evaluated in the short and midterm, but not in the long term. This retrospective multicenter European study is the continuation of an already published series dealing with short- and midterm anatomic results and analyzes long-term data in patients treated with the WEB-DL. MATERIALS AND METHODS: Twelve European neurointerventional centers initially participated in the study. In addition to data collected for the initial publication, images obtained at long-term follow-up were collected and independently analyzed by the same experienced interventional neuroradiologist. RESULTS: Of the initial 45 patients, 26 (20 women and 6 men; 35-73 years of age; mean, 55.2 ± 10.6 years; median, 55.5 years) with 26 aneurysms treated with the WEB-DL device had long-term follow-up (median, 27.4 months). Three of 26 patients (11.5%) were retreated between short- and midterm follow-up, and none, between mid- and long-term follow-up. Long-term aneurysm occlusion in the 19 patients treated with the WEB only and not retreated during follow-up was complete occlusion in 13/19 patients (68.4%), including aneurysms with opacification of the proximal recess in 9/19 patients (47.4%), neck remnant in 3/19 patients (15.8%), and aneurysm remnant in 3/19 patients (15.8%). In all patients (100.0%), aneurysm occlusion was stable between midterm and long-term follow-up. CONCLUSIONS: The results suggest that WEB treatment of wide-neck bifurcation aneurysms offers long-term stable occlusion.
BACKGROUND AND PURPOSE: Flow disruption with the WEB-DL device has been used safely for the treatment of wide-neck bifurcation aneurysms. The stability of aneurysm occlusion after this treatment was evaluated in the short and midterm, but not in the long term. This retrospective multicenter European study is the continuation of an already published series dealing with short- and midterm anatomic results and analyzes long-term data in patients treated with the WEB-DL. MATERIALS AND METHODS: Twelve European neurointerventional centers initially participated in the study. In addition to data collected for the initial publication, images obtained at long-term follow-up were collected and independently analyzed by the same experienced interventional neuroradiologist. RESULTS: Of the initial 45 patients, 26 (20 women and 6 men; 35-73 years of age; mean, 55.2 ± 10.6 years; median, 55.5 years) with 26 aneurysms treated with the WEB-DL device had long-term follow-up (median, 27.4 months). Three of 26 patients (11.5%) were retreated between short- and midterm follow-up, and none, between mid- and long-term follow-up. Long-term aneurysm occlusion in the 19 patients treated with the WEB only and not retreated during follow-up was complete occlusion in 13/19 patients (68.4%), including aneurysms with opacification of the proximal recess in 9/19 patients (47.4%), neck remnant in 3/19 patients (15.8%), and aneurysm remnant in 3/19 patients (15.8%). In all patients (100.0%), aneurysm occlusion was stable between midterm and long-term follow-up. CONCLUSIONS: The results suggest that WEB treatment of wide-neck bifurcation aneurysms offers long-term stable occlusion.
Authors: Andrew Molyneux; Richard Kerr; Irene Stratton; Peter Sandercock; Mike Clarke; Julia Shrimpton; Rury Holman Journal: Lancet Date: 2002-10-26 Impact factor: 79.321
Authors: L Pierot; J Moret; F Turjman; D Herbreteau; H Raoult; X Barreau; S Velasco; H Desal; A-C Januel; P Courtheoux; J-Y Gauvrit; C Cognard; S Soize; A Molyneux; L Spelle Journal: AJNR Am J Neuroradiol Date: 2015-02-05 Impact factor: 3.825
Authors: L Pierot; T Liebig; V Sychra; K Kadziolka; F Dorn; C Strasilla; C Kabbasch; J Klisch Journal: AJNR Am J Neuroradiol Date: 2012-06-07 Impact factor: 3.825
Authors: Laurent Pierot; Vincent Costalat; Jacques Moret; Istvan Szikora; Joachim Klisch; Denis Herbreteau; Markus Holtmannspötter; Werner Weber; Anne-Christine Januel; Thomas Liebig; Vojtech Sychra; Christoph Strasilla; Christophe Cognard; Alain Bonafé; Andrew Molyneux; James V Byrne; Laurent Spelle Journal: J Neurosurg Date: 2015-09-18 Impact factor: 5.115
Authors: L Pierot; J Moret; F Turjman; D Herbreteau; H Raoult; X Barreau; S Velasco; H Desal; A-C Januel; P Courtheoux; J-Y Gauvrit; C Cognard; A Molyneux; J Byrne; L Spelle Journal: AJNR Am J Neuroradiol Date: 2015-10-29 Impact factor: 3.825
Authors: L Goertz; T Liebig; E Siebert; M Herzberg; L Pennig; M Schlamann; J Borggrefe; B Krischek; F Dorn; C Kabbasch Journal: AJNR Am J Neuroradiol Date: 2019-09-05 Impact factor: 3.825
Authors: D Herbreteau; R Bibi; A P Narata; K Janot; C Papagiannaki; S Soize; L Pierot Journal: AJNR Am J Neuroradiol Date: 2016-08-18 Impact factor: 3.825