Literature DB >> 26225342

Treatment options of lymphangioma circumscriptum.

Neerja Puri1.   

Abstract

Entities:  

Year:  2015        PMID: 26225342      PMCID: PMC4513417     

Source DB:  PubMed          Journal:  Indian Dermatol Online J        ISSN: 2229-5178


× No keyword cloud information.
Sir, The article by Ayse Serap Karadag, Emin Ozlu, Seyma Özkanlı, Tugba Kevser Uzuncakmak, Necmettin Akdeniz[1] is interesting. Lymphangiomas are uncommon, hamartomatous malformations of the lymphatic system that involve the skin and subcutaneous tissues.[2] These lesions are divided into two major groups based on the depth and the size of these abnormal lymph vessels. The group with superficial vesicles is called lymphangioma circumscriptum (LC), and the deep-seated group includes cavernous lymphangioma and cystic hygroma. Various modalities include surgical excision, laser therapy, sclerotherapy, electrocoagulation, and cryosurgery. Carbon dioxide laser vaporizes the underlying tissues and seals the lymphatic channels.[3] If the laser energy does not penetrate deep enough into the dermis and/or subcutaneous tissue, the patient will only achieve shortterm palliative symptomatic relief and will have lesion recurrence. Furthermore, energy delivered into deeper structures requires large amounts of local anesthesia (injection or tumescent) because of pain during delivery and may be followed by prolonged healing times with the potential for scarring, prolonged erythema, or postinflammatory hyperpigmentation. Pulsed dye laser (PDL) emits highenergy laser light in ultrashort pulse durations, allowing for specific targeting of the chromophore hemoglobin (585–595 nm) in and around vessels without damaging the surrounding tissues.[4] The effectiveness of PDL in the treatment of LC can be limited by the minimal hemoglobin as a chromophore, because the dilated lymphatic channels contain serosanguineous fluid in dilated lymphatic channels. Sclerotherapy involves injecting detergent sclerosants, chemical irritants, or hyperosmolar agents into the lymphatic malformations to destroy the aberrant vessels. Injectable corticosteroids, tetracycline, 50% dextrose solution, and hyperosmolar saline have all been used in case reports and preliminary trials.[56] For sclerotherapy, intralesional injection of 1% sodium tetradecyl sulfate is used with a very good result. Sclerotherapy using sodium tetradecyl sulfate can be considered a successful minimally invasive treatment option for LC. Depending on the study, recurrence rates vary from 58% to 100%. Cryotherapy utilizes very low temperatures to cause immediate vasoconstriction followed by reactive vasodilation, in turn producing cellular necrosis and healing by secondary intention. Recently, imiquimod cream has been used successfully. Imiquimod induces cellular production of endogenous interferons and interleukins.[7] Efficacy in these patients is likely related to the ability to inhibit vessel formation and induce endothelial cell apoptosis. Surgical excision is regarded as the most definitive treatment, giving the highest chance of cure with a recurrence rate of 17% to 23%.[8] By completely excising the subcutaneous cisterns and removing the source of the vesicles, it is possible to eliminate the cutaneous manifestations. Whereas surgical excision offers definitive treatment, it also involves significant risks including scarring, keloid formation, hematoma, wound infection, and nerve injury. Surgery gives the lowest rates of recurrence, but has the highest risk of complications.[9] However, this may not be feasible in some situations when the involvement is extensive. Recurrence is the rule with other forms of destructive therapy. To conclude, clinicians should discuss goals of treatments with patients when designing a therapeutic plan.
  9 in total

1.  Lymphangioma circumscriptum: treatment with hypertonic saline sclerotherapy.

Authors:  Joseph B Bikowski; Anna Margarita G Dumont
Journal:  J Am Acad Dermatol       Date:  2005-09       Impact factor: 11.527

2.  The pathology of lymphangioma circumscriptum.

Authors:  I W Whimster
Journal:  Br J Dermatol       Date:  1976-05       Impact factor: 9.302

3.  Lymphangioma circumscriptum: pitfalls and problems in definitive management.

Authors:  Jeremy Bond; Mohammed Haj Basheer; Derek Gordon
Journal:  Dermatol Surg       Date:  2007-12-19       Impact factor: 3.398

4.  Treatment of lymphangioma circumscriptum with topical imiquimod 5% cream.

Authors:  Jian-You Wang; Lun-Fei Liu; Xiao-Hong Mao
Journal:  Dermatol Surg       Date:  2012-07-17       Impact factor: 3.398

5.  Lymphangioma circumscriptum treated with pulsed dye laser.

Authors:  C H Lai; S G Hanson; S B Mallory
Journal:  Pediatr Dermatol       Date:  2001 Nov-Dec       Impact factor: 1.588

6.  Surgical management of 'lymphangioma circumscriptum'.

Authors:  N L Browse; I Whimster; G Stewart; C W Helm; J J Wood
Journal:  Br J Surg       Date:  1986-07       Impact factor: 6.939

7.  Lymphangioma circumscriptum: review and evaluation of carbon dioxide laser vaporization.

Authors:  Y D Eliezri; J A Sklar
Journal:  J Dermatol Surg Oncol       Date:  1988-04

8.  Microcystic lymphatic malformation (lymphangioma circumscriptum) treated using a minimally invasive technique of radiofrequency ablation and sclerotherapy.

Authors:  Khunger Niti; Pahwa Manish
Journal:  Dermatol Surg       Date:  2010-11       Impact factor: 3.398

9.  Two cases of lymphangioma circumscriptum successfully treated with pulsed dye laser and cryotherapy.

Authors:  Ayse Serap Karadag; Emin Ozlu; Seyma Özkanlı; Tugba Kevser Uzuncakmak; Necmettin Akdeniz
Journal:  Indian Dermatol Online J       Date:  2015 Jul-Aug
  9 in total
  2 in total

1.  Lipectomy for Symptomatic Relief of Lymphangioma Circumscriptum.

Authors:  Smriti Shrestha; Riyaz Shrestha; Manindra Manandhar
Journal:  J Clin Aesthet Dermatol       Date:  2020-08-01

2.  Acquired Lymphangioma Circumscriptum Post-neonatal Circumcision.

Authors:  Jad A Degheili; Tag Keun Yoo; Sara Trincao-Batra; Jun Ho Lee
Journal:  Turk Arch Pediatr       Date:  2021-09
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.