Hua Xiao1, Pingli Xie2, Kunyan Zhou1, Xiaoxin Qiu1, Yuan Hong1, Jingshi Liu1, Yongzhong Ouyang1, Tang Ming1, Hailong Xie1, Xiaohong Wang1, Haizhen Zhu1, Man Xia3, Chaohui Zuo1. 1. Department of Gastroduodenal and Pancreatic Surgery, Translation Medicine Research Center of Liver Cancer, Hunan Province Tumor Hospital & Affiliated Tumor Hospital of Xiangya Medical School, Central South University 283 Tongzipo Road, Changsha 410013, Hunan Province, China. 2. Key Laboratory of Carcinogenesis and Cancer Invasion, Tumor Immunobiology Laboratory of Cancer Research Institute, Ministry of Education, Ministry of Health, Central South University 110 Xiangya Road, Changsha 410078, Hunan Province, China. 3. Department of Gynaecological Oncology, Hunan Province Tumor Hospital & Affiliated Tumor Hospital of Xiangya Medical School, Central South University 283 Tongzipo Road, Changsha 410013, Hunan Province, China.
Abstract
OBJECTIVE: The objective of the present study was to explore the major risk factors of surgical complications using the Clavien-Dindo classification. METHODS: The case-control design was used. A total of 1049 patients who underwent radical gastrectomy in Hunan Cancer Hospital between October 2010 and August 2014 were retrospectively analyzed, including 122 patients (11.6%) with complications and 927 patients (88.4%) with no complications. Risk factors were evaluated. RESULTS: Following radical gastrectomy, 122 patients (11.6%) experienced a total of 151 complications. The incidence of Stages II, IIIa, IIIb, IVa, IVb and V complications was 9.6% (n = 101), 2.5% (n = 26), 1.0% (n = 11), 0.8% (n = 8), 0% (n = 0), and 0.5% (n = 5), respectively. The incidence of severe complications (Stage ≥ IIIa) was 4.8% (n = 50). Multivariate analysis showed that combined resection (Odds Ratio [OR] = 3.36, 95% confidence interval [CI]: 1.71~6.60, P < 0.01), perioperative blood transfusion (OR = 2.13, 95% CI: 1.38-3.29, P < 0.01), and BMI ≥ 25 kg/m(2) (OR = 1.98, 95% CI: 1.16-3.40, P = 0.01) were independent risk factors of complications. CONCLUSIONS: Combined resection, perioperative blood transfusion, and BMI ≥ 25 kg/m(2) are positively correlated with complications.
OBJECTIVE: The objective of the present study was to explore the major risk factors of surgical complications using the Clavien-Dindo classification. METHODS: The case-control design was used. A total of 1049 patients who underwent radical gastrectomy in Hunan Cancer Hospital between October 2010 and August 2014 were retrospectively analyzed, including 122 patients (11.6%) with complications and 927 patients (88.4%) with no complications. Risk factors were evaluated. RESULTS: Following radical gastrectomy, 122 patients (11.6%) experienced a total of 151 complications. The incidence of Stages II, IIIa, IIIb, IVa, IVb and V complications was 9.6% (n = 101), 2.5% (n = 26), 1.0% (n = 11), 0.8% (n = 8), 0% (n = 0), and 0.5% (n = 5), respectively. The incidence of severe complications (Stage ≥ IIIa) was 4.8% (n = 50). Multivariate analysis showed that combined resection (Odds Ratio [OR] = 3.36, 95% confidence interval [CI]: 1.71~6.60, P < 0.01), perioperative blood transfusion (OR = 2.13, 95% CI: 1.38-3.29, P < 0.01), and BMI ≥ 25 kg/m(2) (OR = 1.98, 95% CI: 1.16-3.40, P = 0.01) were independent risk factors of complications. CONCLUSIONS: Combined resection, perioperative blood transfusion, and BMI ≥ 25 kg/m(2) are positively correlated with complications.
Authors: Kari L Colen; Stuart G Marcus; Elliot Newman; Russell S Berman; Herman Yee; Spiros P Hiotis Journal: J Gastrointest Surg Date: 2004-11 Impact factor: 3.452
Authors: Andrew C Bernard; Daniel L Davenport; Phillip K Chang; Taylor B Vaughan; Joseph B Zwischenberger Journal: J Am Coll Surg Date: 2009-03-26 Impact factor: 6.113
Authors: A Winter; M M Maurer; M Schmelzle; T Malinka; M Biebl; P Fikatas; D Kröll; I M Sauer; M Hippler-Benscheidt; J Pratschke; S Chopra Journal: Chirurg Date: 2021-08-18 Impact factor: 0.955
Authors: Huizheng Bao; Na Xu; Zhongkun Li; Hongtao Ren; Hong Xia; Na Li; Hao Yu; Janbiao Wei; Chengyi Jiang; Lu Liu Journal: Medicine (Baltimore) Date: 2017-05 Impact factor: 1.889