Literature DB >> 26220944

Juvenile Toxicology: Relevance and Challenges for Toxicologists and Pathologists.

Amera K Remick1, Natasha R Catlin2, Erin M Quist3, Thomas J Steinbach4, Darlene Dixon5.   

Abstract

The Society of Toxicologic Pathology (STP) Education Committee and the STP Reproductive Special Interest Group held a North Carolina regional meeting entitled, "Juvenile Toxicology: Relevance and Challenges for Toxicologists and Pathologists" on March 13, 2015, at the National Institute of Environmental Health Sciences/National Toxicology Program in Research Triangle Park, North Carolina. The purpose of this regional meeting was to familiarize attendees with the topic of juvenile toxicity testing and discuss its relevance to clinical pediatric medicine, regulatory perspectives, challenges of appropriate study design confronted by toxicologists, and challenges of histopathologic examination and interpretation of juvenile tissues faced by pathologists. The 1-day meeting was a success with over 60 attendees representing industry, government, research organizations, and academia.
© 2015 by The Author(s).

Entities:  

Keywords:  developmental pathology; drug development; pediatrics; pharmaceutical development/products; preclinical safety assessment/risk management; toxicologic pathology

Mesh:

Year:  2015        PMID: 26220944      PMCID: PMC4670269          DOI: 10.1177/0192623315595883

Source DB:  PubMed          Journal:  Toxicol Pathol        ISSN: 0192-6233            Impact factor:   1.902


  60 in total

Review 1.  Postnatal anatomical and functional development of the heart: a species comparison.

Authors:  Kok Wah Hew; Kit A Keller
Journal:  Birth Defects Res B Dev Reprod Toxicol       Date:  2003-08

Review 2.  Species comparison of lung development.

Authors:  Tracey Zoetis; Mark E Hurtt
Journal:  Birth Defects Res B Dev Reprod Toxicol       Date:  2003-04

Review 3.  Preclinical safety evaluations supporting pediatric drug development with biopharmaceuticals: strategy, challenges, current practices.

Authors:  LaRonda L Morford; Christopher J Bowman; Diann L Blanset; Ingrid B Bøgh; Gary J Chellman; Wendy G Halpern; Gerhard F Weinbauer; Timothy P Coogan
Journal:  Birth Defects Res B Dev Reprod Toxicol       Date:  2011-07-18

4.  Regulatory Forum opinion piece: New testing paradigms for reproductive and developmental toxicity--the NTP modified one generation study and OECD 443.

Authors:  Paul M D Foster
Journal:  Toxicol Pathol       Date:  2014-05-26       Impact factor: 1.902

5.  In utero and lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) affects tooth development in rhesus monkeys.

Authors:  Iku Yasuda; Mineo Yasuda; Hiroshi Sumida; Hideshi Tsusaki; Akihiro Arima; Toshio Ihara; Shunichiro Kubota; Kazuo Asaoka; Kazuhiro Tsuga; Yasumasa Akagawa
Journal:  Reprod Toxicol       Date:  2005 May-Jun       Impact factor: 3.143

6.  Changing numbers of neuronal and non-neuronal cells underlie postnatal brain growth in the rat.

Authors:  Fabiana Bandeira; Roberto Lent; Suzana Herculano-Houzel
Journal:  Proc Natl Acad Sci U S A       Date:  2009-08-04       Impact factor: 11.205

7.  Inhaled corticosteroids in children with persistent asthma: effects on growth.

Authors:  Linjie Zhang; Sílvio O M Prietsch; Francine M Ducharme
Journal:  Evid Based Child Health       Date:  2014-12

8.  Histologic features of prepubertal and pubertal reproductive development in female Sprague-Dawley rats.

Authors:  Catherine A Picut; Amera K Remick; Midori G Asakawa; Michelle L Simons; George A Parker
Journal:  Toxicol Pathol       Date:  2013-04-18       Impact factor: 1.902

9.  Postnatal development of the testis in the rat: morphologic study and correlation of morphology to neuroendocrine parameters.

Authors:  Catherine A Picut; Amera K Remick; Eveline P C T de Rijk; Michelle L Simons; Donald G Stump; George A Parker
Journal:  Toxicol Pathol       Date:  2014-09-11       Impact factor: 1.902

10.  The effects of chronic methylphenidate administration on operant test battery performance in juvenile rhesus monkeys.

Authors:  J S Rodriguez; S M Morris; C E Hotchkiss; D R Doerge; R R Allen; D R Mattison; M G Paule
Journal:  Neurotoxicol Teratol       Date:  2009-09-06       Impact factor: 3.763

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  4 in total

Review 1.  Comparing Postnatal Development of Gonadal Hormones and Associated Social Behaviors in Rats, Mice, and Humans.

Authors:  Margaret R Bell
Journal:  Endocrinology       Date:  2018-07-01       Impact factor: 4.736

2.  Differentiating between Testicular Toxicity and Sexual Immaturity in Ortho-phthalaldehyde Inhalation Toxicity Studies in Rats and Mice.

Authors:  Natasha R Catlin; Cynthia J Willson; Dianne M Creasy; Deepa B Rao; Grace E Kissling; Barry S McIntyre; Michael Wyde
Journal:  Toxicol Pathol       Date:  2018-09-27       Impact factor: 1.902

Review 3.  A brief review of kidney development, maturation, developmental abnormalities, and drug toxicity: juvenile animal relevancy.

Authors:  John Curtis Seely
Journal:  J Toxicol Pathol       Date:  2017-02-11       Impact factor: 1.628

4.  Histopathological evaluation of crypt fission during intestinal development in neonatal mice.

Authors:  Masaki Yamazaki; Etsuko Fujii; Takeshi Watanabe; Atsuhiko Kato; Masami Suzuki
Journal:  J Toxicol Pathol       Date:  2019-09-23       Impact factor: 1.628

  4 in total

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