BACKGROUND: Scanty data on the performance of the new 25-gauge Procore™ biopsy needle are available. METHODS: Consecutive patients who underwent endoscopic ultrasound-guided fine needle biopsy (EUS-FNB) using the 25G Procore™ were retrospectively retrieved. All samples were independently reviewed by 3 pathologists for the following: histological, cytological or no specimen, neoplasia, diagnostic or non-diagnostic. Diagnostic accuracy and inter-rater concordance among pathologists were calculated. RESULTS: 94 patients underwent EUS-FNB of 101 sites (69 solid masses, 25 lymph nodes, 5 wall thickening). Forty-one biopsies (40.5%) were classified as histological samples by at least two pathologists, 29 as cytological (28.7%), 31 had no sample (30.7%). Good and almost perfect agreements among pathologists in defining cytological vs. histological samples (k 0.82; 95% CI: 0.74-0.90), diagnostic vs. non-diagnostic (k 0.95; 95% CI: 0.85-1.00) and neoplastic vs. non-neoplastic (k 0.94; 95% CI: 0.83-1.00). According to consensus rating, 61 cases were diagnostic samples (60.4%). Histological samples were more likely to lead to a correct diagnosis (OR, 4.1; 95% P=0.027), while neoplastic lesions were less likely to be correctly classified than benign (OR, 0.11; P=0.04). CONCLUSIONS: EUS-FNB with the Procore™ 25G needle provided samples for histological examination in only 40% of the cases, with 31% of inadequate specimens, despite excellent results in term of inter-observer variability.
BACKGROUND: Scanty data on the performance of the new 25-gauge Procore™ biopsy needle are available. METHODS: Consecutive patients who underwent endoscopic ultrasound-guided fine needle biopsy (EUS-FNB) using the 25G Procore™ were retrospectively retrieved. All samples were independently reviewed by 3 pathologists for the following: histological, cytological or no specimen, neoplasia, diagnostic or non-diagnostic. Diagnostic accuracy and inter-rater concordance among pathologists were calculated. RESULTS: 94 patients underwent EUS-FNB of 101 sites (69 solid masses, 25 lymph nodes, 5 wall thickening). Forty-one biopsies (40.5%) were classified as histological samples by at least two pathologists, 29 as cytological (28.7%), 31 had no sample (30.7%). Good and almost perfect agreements among pathologists in defining cytological vs. histological samples (k 0.82; 95% CI: 0.74-0.90), diagnostic vs. non-diagnostic (k 0.95; 95% CI: 0.85-1.00) and neoplastic vs. non-neoplastic (k 0.94; 95% CI: 0.83-1.00). According to consensus rating, 61 cases were diagnostic samples (60.4%). Histological samples were more likely to lead to a correct diagnosis (OR, 4.1; 95% P=0.027), while neoplastic lesions were less likely to be correctly classified than benign (OR, 0.11; P=0.04). CONCLUSIONS: EUS-FNB with the Procore™ 25G needle provided samples for histological examination in only 40% of the cases, with 31% of inadequate specimens, despite excellent results in term of inter-observer variability.
Authors: Priscilla A van Riet; Djuna L Cahen; Katharina Biermann; Bettina Hansen; Alberto Larghi; Guido Rindi; Giovanni Fellegara; Paolo Arcidiacono; Claudio Doglioni; Nicola Liberta Decarli; Julio Iglesias-Garcia; Ihab Abdulkader; Hector Lazare Iglesias; Masayuki Kitano; Takaaki Chikugo; Satoru Yasukawa; Hans van der Valk; Nam Quoc Nguyen; Andrew Ruszkiewicz; Marc Giovannini; Flora Poizat; Schalk van der Merwe; Tania Roskams; Erwin Santo; Silvia Marmor; Kenneth Chang; Fritz Lin; James Farrell; Marie Robert; Juan Carlos Bucobo; Alan Heimann; Francisco Baldaque-Silva; Carlos Fernández Moro; Marco J Bruno Journal: Dig Endosc Date: 2019-07-10 Impact factor: 7.559
Authors: Diogo Turiani Hourneaux Moura; Thomas R McCarty; Pichamol Jirapinyo; Igor Braga Ribeiro; Galileu Ferreira Ayala Farias; Antonio Coutinho Madruga-Neto; Marvin Ryou; Christopher C Thompson Journal: World J Clin Cases Date: 2021-12-06 Impact factor: 1.337