Literature DB >> 26214544

Effect of patient choice in an adaptive sequential randomization trial of treatment for alcohol and cocaine dependence.

James R McKay1, Michelle L Drapkin2, Deborah H A Van Horn1, Kevin G Lynch1, David W Oslin1, Dominick DePhilippis1, Megan Ivey1, John S Cacciola3.   

Abstract

OBJECTIVE: To evaluate the effect of providing choice of treatment alternatives to patients who fail to engage in or drop out of intensive outpatient programs (IOPs) for substance dependence.
METHOD: Alcohol- and/or cocaine-dependent patients (N = 500) participated in a sequential, multiple-assignment, randomized trial (SMART). Those who failed to engage in an IOP at Week 2 (N = 189) or who dropped out after engagement (N = 84) were randomized for motivational-interviewing (MI) telephone calls that focused on engagement in an IOP (MI-IOP) or provided a choice of IOP type or 3 treatment options (MI-PC, or patient choice). Those not engaged at both 2 and 8 weeks (N = 102) were re-randomized either to MI-PC or no further outreach. Outcomes were treatment attendance and measures of alcohol and cocaine use obtained at 1, 2, 3, and 6 months.
RESULTS: MI-PC produced better attendance than comparison conditions in patients who dropped out after initial engagement and in those re-randomized at 8 weeks. However, contrary to study hypotheses, MI-IOP produced significantly better alcohol-use outcomes than MI-PC in alcohol-dependent patients not engaged at Week 2. There were no other significant differences between treatment conditions on other main-effect analyses with alcohol- or cocaine-outcome measures.
CONCLUSION: Providing treatment options via telephone calls to patients who failed to engage in IOP did not produce better substance-use outcomes than outreach calls focused on engagement in IOP. Future researchers should investigate the potential benefits of choice at other points in treatment (e.g., at intake) as well as choice of other combinations of treatments. (c) 2015 APA, all rights reserved).

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Year:  2015        PMID: 26214544      PMCID: PMC5823027          DOI: 10.1037/a0039534

Source DB:  PubMed          Journal:  J Consult Clin Psychol        ISSN: 0022-006X


  33 in total

1.  A randomized trial of extended telephone-based continuing care for alcohol dependence: within-treatment substance use outcomes.

Authors:  James R McKay; Deborah H A Van Horn; David W Oslin; Kevin G Lynch; Megan Ivey; Kathleen Ward; Michelle L Drapkin; Julie R Becher; Donna M Coviello
Journal:  J Consult Clin Psychol       Date:  2010-12

2.  The impact of client treatment preferences on outcome: a meta-analysis.

Authors:  Joshua K Swift; Jennifer L Callahan
Journal:  J Clin Psychol       Date:  2009-04

3.  Talk is cheap: measuring drinking outcomes in clinical trials.

Authors:  T F Babor; K Steinberg; R Anton; F Del Boca
Journal:  J Stud Alcohol       Date:  2000-01

4.  A randomized clinical trial of alcohol care management delivered in Department of Veterans Affairs primary care clinics versus specialty addiction treatment.

Authors:  David W Oslin; Kevin G Lynch; Stephen A Maisto; Larry J Lantinga; James R McKay; Kyle Possemato; Erin Ingram; Michael Wierzbicki
Journal:  J Gen Intern Med       Date:  2013-09-20       Impact factor: 5.128

5.  What do women want? Alcohol treatment choices, treatment entry and retention.

Authors:  Barbara S McCrady; Elizabeth E Epstein; Sharon Cook; Noelle K Jensen; Benjamin O Ladd
Journal:  Psychol Addict Behav       Date:  2011-09

6.  Reliability of alcohol abusers' self-reports of drinking behavior.

Authors:  L C Sobell; S A Maisto; M B Sobell; A M Cooper
Journal:  Behav Res Ther       Date:  1979

7.  Random versus nonrandom assignment in the evaluation of treatment for cocaine abusers.

Authors:  J R McKay; A I Alterman; A T McLellan; C R Boardman; F D Mulvaney; C P O'Brien
Journal:  J Consult Clin Psychol       Date:  1998-08

Review 8.  Patient preferences for shared decisions: a systematic review.

Authors:  Betty Chewning; Carma L Bylund; Bupendra Shah; Neeraj K Arora; Jennifer A Gueguen; Gregory Makoul
Journal:  Patient Educ Couns       Date:  2011-04-06

Review 9.  Impact of participant and physician intervention preferences on randomized trials: a systematic review.

Authors:  Michael King; Irwin Nazareth; Fiona Lampe; Peter Bower; Martin Chandler; Maria Morou; Bonnie Sibbald; Rosalind Lai
Journal:  JAMA       Date:  2005-03-02       Impact factor: 56.272

10.  Effect of random versus nonrandom assignment in a comparison of inpatient and day hospital rehabilitation for male alcoholics.

Authors:  J R McKay; A I Alterman; A T McLellan; E C Snider; C P O'Brien
Journal:  J Consult Clin Psychol       Date:  1995-02
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  6 in total

1.  Comparing cluster-level dynamic treatment regimens using sequential, multiple assignment, randomized trials: Regression estimation and sample size considerations.

Authors:  Timothy NeCamp; Amy Kilbourne; Daniel Almirall
Journal:  Stat Methods Med Res       Date:  2017-06-19       Impact factor: 3.021

2.  Developing adaptive interventions for adolescent substance use treatment settings: protocol of an observational, mixed-methods project.

Authors:  Sean Grant; Denis Agniel; Daniel Almirall; Q Burkhart; Sarah B Hunter; Daniel F McCaffrey; Eric R Pedersen; Rajeev Ramchand; Beth Ann Griffin
Journal:  Addict Sci Clin Pract       Date:  2017-12-19

3.  Bayesian set of best dynamic treatment regimes: Construction and sample size calculation for SMARTs with binary outcomes.

Authors:  William J Artman; Brent A Johnson; Kevin G Lynch; James R McKay; Ashkan Ertefaie
Journal:  Stat Med       Date:  2022-02-06       Impact factor: 2.497

4.  Noninferiority and equivalence tests in sequential, multiple assignment, randomized trials (SMARTs).

Authors:  Palash Ghosh; Inbal Nahum-Shani; Bonnie Spring; Bibhas Chakraborty
Journal:  Psychol Methods       Date:  2019-09-09

5.  Association of Patient Treatment Preference With Dropout and Clinical Outcomes in Adult Psychosocial Mental Health Interventions: A Systematic Review and Meta-analysis.

Authors:  Emma Windle; Helena Tee; Alina Sabitova; Nikolina Jovanovic; Stefan Priebe; Catherine Carr
Journal:  JAMA Psychiatry       Date:  2020-03-01       Impact factor: 21.596

Review 6.  Sample size considerations for comparing dynamic treatment regimens in a sequential multiple-assignment randomized trial with a continuous longitudinal outcome.

Authors:  Nicholas J Seewald; Kelley M Kidwell; Inbal Nahum-Shani; Tianshuang Wu; James R McKay; Daniel Almirall
Journal:  Stat Methods Med Res       Date:  2019-10-01       Impact factor: 3.021

  6 in total

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