| Literature DB >> 2620938 |
P K Joseph, K R Rao, C S Sundaresh.
Abstract
Significant rise in urea and D-aspartate aminotransferase and inhibition of alkaline phosphatase in serum were observed in rats fed garlic extract (2 ml/100 g body wt, intragastrically) for 10 days. The liver showed histological changes. Garlic oil feeding (10 mg/100 g body wt, intragastrically) after 24 hr fasting was found lethal. The cause of death appears to be acute pulmonary oedema. On histological examination, all the organs of the dead rats revealed severe congestion. However, similar feeding of garlic oil was well tolerated by rats in the fed state. Also, 24 hr fasted rats could tolerate this dose of garlic oil, provided they were previously adapted to garlic oil feeding.Entities:
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Year: 1989 PMID： 2620938
Source DB: PubMed Journal: Indian J Exp Biol ISSN： 0019-5189 Impact factor: 0.818