Literature DB >> 26205467

Assessing drug safety in human tissues - what are the barriers?

Anthony Holmes1, Frank Bonner2, David Jones3.   

Abstract

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Year:  2015        PMID： 26205467     DOI： 10.1038/nrd4662

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN： 1474-1776            Impact factor:   84.694


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  3 in total

Review 1.  Organs-on-chips at the frontiers of drug discovery.

Authors:  Eric W Esch; Anthony Bahinski; Dongeun Huh
Journal:  Nat Rev Drug Discov       Date:  2015-03-20       Impact factor: 84.694

Review 2.  Accelerating drug discovery via organs-on-chips.

Authors:  Chung Yu Chan; Po-Hsun Huang; Feng Guo; Xiaoyun Ding; Vivek Kapur; John D Mai; Po Ki Yuen; Tony Jun Huang
Journal:  Lab Chip       Date:  2013-12-21       Impact factor: 6.799

Review 3.  The future of the patient-specific Body-on-a-chip.

Authors:  Adam Williamson; Sukhdeep Singh; Uta Fernekorn; Andreas Schober
Journal:  Lab Chip       Date:  2013-09-21       Impact factor: 6.799
  3 in total
  7 in total

1.  Human ex-vivo action potential model for pro-arrhythmia risk assessment.

Authors:  Guy Page; Phachareeya Ratchada; Yannick Miron; Guido Steiner; Andre Ghetti; Paul E Miller; Jack A Reynolds; Ken Wang; Andrea Greiter-Wilke; Liudmila Polonchuk; Martin Traebert; Gary A Gintant; Najah Abi-Gerges
Journal:  J Pharmacol Toxicol Methods       Date:  2016-05-25       Impact factor: 1.950

Review 2.  Cardiovascular Organ-on-a-Chip Platforms for Drug Discovery and Development.

Authors:  João Ribas; Hossein Sadeghi; Amir Manbachi; Jeroen Leijten; Katelyn Brinegar; Yu Shrike Zhang; Lino Ferreira; Ali Khademhosseini
Journal:  Appl In Vitro Toxicol       Date:  2016-06-01

Review 3.  Human-Derived Organ-on-a-Chip for Personalized Drug Development.

Authors:  Yasamin A Jodat; Min G Kang; Kiavash Kiaee; Gyeong J Kim; Angel F H Martinez; Aliza Rosenkranz; Hojae Bae; Su R Shin
Journal:  Curr Pharm Des       Date:  2018       Impact factor: 3.116

Review 4.  Managing the challenge of drug-induced liver injury: a roadmap for the development and deployment of preclinical predictive models.

Authors:  Richard J Weaver; Eric A Blomme; Amy E Chadwick; Ian M Copple; Helga H J Gerets; Christopher E Goldring; Andre Guillouzo; Philip G Hewitt; Magnus Ingelman-Sundberg; Klaus Gjervig Jensen; Satu Juhila; Ursula Klingmüller; Gilles Labbe; Michael J Liguori; Cerys A Lovatt; Paul Morgan; Dean J Naisbitt; Raymond H H Pieters; Jan Snoeys; Bob van de Water; Dominic P Williams; B Kevin Park
Journal:  Nat Rev Drug Discov       Date:  2019-11-20       Impact factor: 84.694

5.  Adult Human Primary Cardiomyocyte-Based Model for the Simultaneous Prediction of Drug-Induced Inotropic and Pro-arrhythmia Risk.

Authors:  Nathalie Nguyen; William Nguyen; Brynna Nguyenton; Phachareeya Ratchada; Guy Page; Paul E Miller; Andre Ghetti; Najah Abi-Gerges
Journal:  Front Physiol       Date:  2017-12-19       Impact factor: 4.566

6.  Opportunities to Apply the 3Rs in Safety Assessment Programs.

Authors:  Fiona Sewell; Joanna Edwards; Helen Prior; Sally Robinson
Journal:  ILAR J       Date:  2016-12

7.  Myocardial slices come to age: an intermediate complexity in vitro cardiac model for translational research.

Authors:  Fotios G Pitoulis; Samuel A Watson; Filippo Perbellini; Cesare M Terracciano
Journal:  Cardiovasc Res       Date:  2020-06-01       Impact factor: 10.787
  7 in total

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