Literature DB >> 26202582

Sub-optimal responders following controlled ovarian stimulation: an overlooked group?

N P Polyzos1, S K Sunkara2.   

Abstract

Individualization of IVF treatment and tailored stimulation based on predicted ovarian response may maximize treatment success and minimize the risks following IVF. Whilst there has been a consensus in defining poor ovarian response and an attempt to elucidate the threshold for excessive ovarian response based on the number of oocytes retrieved following ovarian stimulation, no systematic effort has been made in order to refine the oocyte yield thresholds for a normal responder. In this opinion article we discuss the evidence behind the oocyte number thresholds for the ovarian response categories and present the rationale and merits in recognizing a new, overlooked, ovarian response group: The sub-optimal ovarian responders.
© The Author 2015. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Entities:  

Keywords:  controlled ovarian stimulation; individualized IVF; ovarian response; sub-optimal responders; tailored ovarian stimulation

Mesh：

Year:  2015        PMID： 26202582     DOI： 10.1093/humrep/dev149

Source DB:  PubMed          Journal:  Hum Reprod        ISSN： 0268-1161            Impact factor:   6.918


  20 in total

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3.  Freeze-all cycle for all normal responders?

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Journal:  J Assist Reprod Genet       Date:  2016-11-05       Impact factor: 3.412

4.  Cumulative live birth and surplus embryo incidence after frozen-thaw cycles in PCOS: how many oocytes do we need?

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Review 5.  Regulation of antral follicular growth by an interplay between gonadotropins and their receptors.

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6.  Growth hormone supplementation during ovarian stimulation improves oocyte and embryo outcomes in IVF/PGT-A cycles of women who are not poor responders.

Authors:  Amanda Skillern; Whitney Leonard; Jordyn Pike; Winifred Mak
Journal:  J Assist Reprod Genet       Date:  2021-02-03       Impact factor: 3.412

Review 7.  Dose adjustment of follicle-stimulating hormone (FSH) during ovarian stimulation as part of medically-assisted reproduction in clinical studies: a systematic review covering 10 years (2007-2017).

Authors:  Human Fatemi; Wilma Bilger; Deborah Denis; Georg Griesinger; Antonio La Marca; Salvatore Longobardi; Mary Mahony; Xiaoyan Yin; Thomas D'Hooghe
Journal:  Reprod Biol Endocrinol       Date:  2021-05-11       Impact factor: 5.211

8.  Efficacy and safety of follitropin alfa/lutropin alfa in ART: a randomized controlled trial in poor ovarian responders.

Authors:  P Humaidan; W Chin; D Rogoff; T D'Hooghe; S Longobardi; J Hubbard; J Schertz
Journal:  Hum Reprod       Date:  2017-03-01       Impact factor: 6.918

9.  A freeze-all strategy does not increase live birth rates in women of advanced reproductive age.

Authors:  K Lattes; S López; M A Checa; M Brassesco; D García; R Vassena
Journal:  J Assist Reprod Genet       Date:  2020-09-02       Impact factor: 3.412

10.  The Effect of Dose Adjustments in a Subsequent Cycle of Women With Suboptimal Response Following Conventional Ovarian Stimulation.

Authors:  Panagiotis Drakopoulos; Samuel Santos-Ribeiro; Ernesto Bosch; Juan Garcia-Velasco; Christophe Blockeel; Alessia Romito; Herman Tournaye; Nikolaos P Polyzos
Journal:  Front Endocrinol (Lausanne)       Date:  2018-07-23       Impact factor: 5.555
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