Literature DB >> 26198622

Ultrasmall Gold Nanorod Vesicles with Enhanced Tumor Accumulation and Fast Excretion from the Body for Cancer Therapy.

Jibin Song1,2, Xiangyu Yang2, Orit Jacobson2, Peng Huang2, Xiaolian Sun2, Lisen Lin2, Xuefeng Yan2, Gang Niu2, Qingjie Ma1, Xiaoyuan Chen2.   

Abstract

A new kind of ultrasmall dissociable AuNR@PEG/PLGA vesicles (≈60 nm) (AuNR = gold nanorod; PEG = poly(ethylene glycol); PLGA = poly(lactic-co-glycolic acid)) assembled from small AuNRs (dimension: ≈8 nm × 2 nm) is reported. They exhibit several striking features: prolonged circulation and prominent tumor accumulation; rapid excretion from the body as AuNR@PEG after therapy; enhanced photoacoustic and photo thermal properties; and high photothermal cancer therapy efficacy.
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  biodegradation; nanovesicles; photoacoustic imaging; photothermal effects; ultrasmall gold nanorods

Mesh:

Substances:

Year:  2015        PMID: 26198622     DOI: 10.1002/adma.201502486

Source DB:  PubMed          Journal:  Adv Mater        ISSN: 0935-9648            Impact factor:   30.849


  56 in total

1.  Biomineralization-Inspired Synthesis of Copper Sulfide-Ferritin Nanocages as Cancer Theranostics.

Authors:  Zhantong Wang; Peng Huang; Orit Jacobson; Zhe Wang; Yijing Liu; Lisen Lin; Jing Lin; Nan Lu; Huimin Zhang; Rui Tian; Gang Niu; Gang Liu; Xiaoyuan Chen
Journal:  ACS Nano       Date:  2016-02-18       Impact factor: 15.881

Review 2.  Photoacoustic Molecular Imaging: From Multiscale Biomedical Applications Towards Early-Stage Theranostics.

Authors:  Yajing Liu; Liming Nie; Xiaoyuan Chen
Journal:  Trends Biotechnol       Date:  2016-02-26       Impact factor: 19.536

3.  Near-Infrared Semiconducting Polymer Brush and pH/GSH-Responsive Polyoxometalate Cluster Hybrid Platform for Enhanced Tumor-Specific Phototheranostics.

Authors:  Zhen Yang; Wenpei Fan; Wei Tang; Zheyu Shen; Yunlu Dai; Jibin Song; Zhantong Wang; Yuan Liu; Lisen Lin; Lingling Shan; Yijing Liu; Orit Jacobson; Pengfei Rong; Wei Wang; Xiaoyuan Chen
Journal:  Angew Chem Int Ed Engl       Date:  2018-10-08       Impact factor: 15.336

Review 4.  Amphiphilic-Polymer-Guided Plasmonic Assemblies and Their Biomedical Applications.

Authors:  Jibin Song; Gang Niu; Xiaoyuan Chen
Journal:  Bioconjug Chem       Date:  2016-11-18       Impact factor: 4.774

5.  Mini Gold Nanorods with Tunable Plasmonic Peaks beyond 1000 nm.

Authors:  Huei-Huei Chang; Catherine J Murphy
Journal:  Chem Mater       Date:  2018-01-25       Impact factor: 9.811

6.  Mussel-inspired PLGA/polydopamine core-shell nanoparticle for light induced cancer thermochemotherapy.

Authors:  Huacheng He; Eleni Markoutsa; Yihong Zhan; Jiajia Zhang; Peisheng Xu
Journal:  Acta Biomater       Date:  2017-07-05       Impact factor: 8.947

Review 7.  Positron emission tomography and nanotechnology: A dynamic duo for cancer theranostics.

Authors:  Shreya Goel; Christopher G England; Feng Chen; Weibo Cai
Journal:  Adv Drug Deliv Rev       Date:  2016-08-09       Impact factor: 15.470

8.  Near-Infrared Emission CuInS/ZnS Quantum Dots: All-in-One Theranostic Nanomedicines with Intrinsic Fluorescence/Photoacoustic Imaging for Tumor Phototherapy.

Authors:  Guoxian Lv; Weisheng Guo; Wei Zhang; Tingbin Zhang; Shuyi Li; Shizhu Chen; Ahmed Shaker Eltahan; Dongliang Wang; Yuqing Wang; Jinchao Zhang; Paul C Wang; Jin Chang; Xing-Jie Liang
Journal:  ACS Nano       Date:  2016-09-20       Impact factor: 15.881

9.  Gold Nanoparticle Coated Carbon Nanotube Ring with Enhanced Raman Scattering and Photothermal Conversion Property for Theranostic Applications.

Authors:  Jibin Song; Feng Wang; Xiangyu Yang; Bo Ning; Mary G Harp; Stephen H Culp; Song Hu; Peng Huang; Liming Nie; Jingyi Chen; Xiaoyuan Chen
Journal:  J Am Chem Soc       Date:  2016-05-26       Impact factor: 15.419

10.  Dynamic Positron Emission Tomography Imaging of Renal Clearable Gold Nanoparticles.

Authors:  Feng Chen; Shreya Goel; Reinier Hernandez; Stephen A Graves; Sixiang Shi; Robert J Nickles; Weibo Cai
Journal:  Small       Date:  2016-04-09       Impact factor: 13.281

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