| Literature DB >> 26198622 |
Jibin Song1,2, Xiangyu Yang2, Orit Jacobson2, Peng Huang2, Xiaolian Sun2, Lisen Lin2, Xuefeng Yan2, Gang Niu2, Qingjie Ma1, Xiaoyuan Chen2.
Abstract
A new kind of ultrasmall dissociable AuNR@PEG/PLGA vesicles (≈60 nm) (AuNR = gold nanorod; PEG = poly(ethylene glycol); PLGA = poly(lactic-co-glycolic acid)) assembled from small AuNRs (dimension: ≈8 nm × 2 nm) is reported. They exhibit several striking features: prolonged circulation and prominent tumor accumulation; rapid excretion from the body as AuNR@PEG after therapy; enhanced photoacoustic and photo thermal properties; and high photothermal cancer therapy efficacy.Entities:
Keywords: biodegradation; nanovesicles; photoacoustic imaging; photothermal effects; ultrasmall gold nanorods
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Year: 2015 PMID: 26198622 DOI: 10.1002/adma.201502486
Source DB: PubMed Journal: Adv Mater ISSN: 0935-9648 Impact factor: 30.849