Literature DB >> 26195178

Efficacy of colchicine in a child with relapsing bullous Henoch-Schönlein purpura.

Slimane Allali1, Sylvie Fraitag2, Benjamin Terrier3, Christine Bodemer4, Martin Chalumeau5.   

Abstract

UNLABELLED: Colchicine is not usually considered a treatment option for cutaneous lesions of Henoch-Schönlein purpura (HSP) in children. We report a case of pediatric HSP with severe chronic and relapsing cutaneous manifestations that were resistant to corticosteroids. Colchicine had remarkable therapeutic efficacy, with positive dechallenge and rechallenge, without any adverse effects.
CONCLUSION: Colchicine should be considered for chronic, severe cutaneous lesions of pediatric HSP. WHAT IS KNOWN: Colchicine is not usually considered a treatment option for cutaneous lesions of Henoch-Schönlein purpura (HSP) in children. What is New: We report a case of pediatric HSP with severe cutaneous manifestations that responded well to colchicine. Colchicine should be considered for chronic cutaneous lesions of HSP in children.

Entities:  

Keywords:  Chronic severe cutaneous lesions; Colchicine; Henoch-Schönlein purpura; Immunoglobulin A vasculitis; Leukocytoclastic vasculitis

Mesh:

Substances:

Year:  2015        PMID: 26195178     DOI: 10.1007/s00431-015-2594-5

Source DB:  PubMed          Journal:  Eur J Pediatr        ISSN: 0340-6199            Impact factor:   3.183


  9 in total

1.  Successful treatment of chronic Henoch-Schonlein purpura with colchicine and aspirin.

Authors:  S Padeh; J H Passwell
Journal:  Isr Med Assoc J       Date:  2000-06       Impact factor: 0.892

2.  Bullous lesions in Henoch-Schönlein purpura.

Authors:  Kingsley Han Ngai Chan; William Yuk Ming Tang; Kuen Kong Lo
Journal:  Pediatr Dermatol       Date:  2007 May-Jun       Impact factor: 1.588

3.  Successful treatment of prolonged Henoch-Schönlein purpura with colchicine.

Authors:  Frank T Saulsbury
Journal:  Clin Pediatr (Phila)       Date:  2009-05-21       Impact factor: 1.168

4.  Henoch-Schonlein purpura in Thai children: a report from single center.

Authors:  Pimprae Pengpis; Sukrawan Intrakao; Sookkasem Khositseth
Journal:  J Med Assoc Thai       Date:  2011-12

5.  [Dapsone for chronic skin lesions in 3 children suffering from Henoch-Schönlein vasculitis].

Authors:  N Mazille; D Lipsker; M Fischbach
Journal:  Arch Pediatr       Date:  2011-10-02       Impact factor: 1.180

6.  Prevalence and significance of the MEFV gene mutations in childhood Henoch-Schönlein purpura without FMF symptoms.

Authors:  Cagla Serpil Dogan; Sema Akman; Mustafa Koyun; Turker Bilgen; Elif Comak; Arife Uslu Gokceoglu
Journal:  Rheumatol Int       Date:  2012-03-27       Impact factor: 2.631

Review 7.  Colchicine: old and new.

Authors:  Anastasia Slobodnick; Binita Shah; Michael H Pillinger; Svetlana Krasnokutsky
Journal:  Am J Med       Date:  2014-12-30       Impact factor: 4.965

8.  Randomised, double-blind, placebo-controlled trial to determine whether steroids reduce the incidence and severity of nephropathy in Henoch-Schonlein Purpura (HSP).

Authors:  Jan Dudley; Graham Smith; Anne Llewelyn-Edwards; Kate Bayliss; Katie Pike; Jane Tizard
Journal:  Arch Dis Child       Date:  2013-07-11       Impact factor: 3.791

9.  Colchicine in the treatment of cutaneous leukocytoclastic vasculitis. Results of a prospective, randomized controlled trial.

Authors:  G Sais; A Vidaller; A Jucglà; F Gallardo; J Peyrí
Journal:  Arch Dermatol       Date:  1995-12
  9 in total
  6 in total

Review 1.  Colchicine: an ancient drug with novel applications.

Authors:  B Dasgeb; D Kornreich; K McGuinn; L Okon; I Brownell; D L Sackett
Journal:  Br J Dermatol       Date:  2018-01-03       Impact factor: 9.302

Review 2.  Blistering eruptions in childhood Henoch-Schönlein syndrome: systematic review of the literature.

Authors:  Vera Ramelli; Sebastiano A G Lava; Giacomo D Simonetti; Mario G Bianchetti; Gian Paolo Ramelli; Gregorio P Milani
Journal:  Eur J Pediatr       Date:  2017-02-04       Impact factor: 3.183

3.  Hemorrhagic Bullous Henoch-Schönlein Purpura: Case Report and Review of the Literature.

Authors:  Matthias Nothhaft; Joerg Klepper; Hermann Kneitz; Thomas Meyer; Henning Hamm; Henner Morbach
Journal:  Front Pediatr       Date:  2019-01-22       Impact factor: 3.418

4.  Recurrent Henoch-Schönlein Purpura with bullous rash and pulmonary nodules.

Authors:  Christopher Zheng; Julie Childers; Egla Rabinovich; Kristina Nazareth-Pidgeon
Journal:  Pediatr Rheumatol Online J       Date:  2020-05-24       Impact factor: 3.054

5.  Azathioprine therapy for steroid-resistant Henoch-Schönlein purpura: a report of 6 cases.

Authors:  Lampros Fotis; Paul V Tuttle; Kevin W Baszis; Peri H Pepmueller; Terry L Moore; Andrew J White
Journal:  Pediatr Rheumatol Online J       Date:  2016-06-23       Impact factor: 3.054

6.  Henoch-Schönlein purpura in the third trimester of pregnancy.

Authors:  Ivka Djakovic; Drazan Butorac; Zeljko Vucicevic; Vesna Kosec; Andrea Tesija Kuna; Liborija Lugović-Mihić
Journal:  Biochem Med (Zagreb)       Date:  2018-01-10       Impact factor: 2.313

  6 in total

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