Literature DB >> 21963373

[Dapsone for chronic skin lesions in 3 children suffering from Henoch-Schönlein vasculitis].

N Mazille1, D Lipsker, M Fischbach.   

Abstract

We describe 3 cases of chronic purpuric skin lesions in children suffering from systemic vasculitis: 3 children with Henoch-Schönlein purpura. Dapsone was introduced when skin lesions were recurrent, extensive, and persistent, due to its known ability to act as an anti-IgA and as an anticytotoxic agent against polynuclear neutrophils. Fast and complete but purely suspensive healing of skin lesions was noted. One child developed methemoglobinemia, a known side-effect of dapsone, highlighting the need for adequate prescription and follow-up.
Copyright © 2011 Elsevier Masson SAS. All rights reserved.

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Year:  2011        PMID: 21963373     DOI: 10.1016/j.arcped.2011.08.011

Source DB:  PubMed          Journal:  Arch Pediatr        ISSN: 0929-693X            Impact factor:   1.180


  2 in total

Review 1.  Indications and efficiency of dapsone in IgA vasculitis (Henoch-Schonlein purpura): case series and a review of the literature.

Authors:  Céline Roman; Bogdan Dima; Laurence Muyshont; Thierry Schurmans; Olivier Gilliaux
Journal:  Eur J Pediatr       Date:  2019-06-22       Impact factor: 3.183

2.  Efficacy of colchicine in a child with relapsing bullous Henoch-Schönlein purpura.

Authors:  Slimane Allali; Sylvie Fraitag; Benjamin Terrier; Christine Bodemer; Martin Chalumeau
Journal:  Eur J Pediatr       Date:  2015-07-21       Impact factor: 3.183

  2 in total

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