| Literature DB >> 21963373 |
N Mazille1, D Lipsker, M Fischbach.
Abstract
We describe 3 cases of chronic purpuric skin lesions in children suffering from systemic vasculitis: 3 children with Henoch-Schönlein purpura. Dapsone was introduced when skin lesions were recurrent, extensive, and persistent, due to its known ability to act as an anti-IgA and as an anticytotoxic agent against polynuclear neutrophils. Fast and complete but purely suspensive healing of skin lesions was noted. One child developed methemoglobinemia, a known side-effect of dapsone, highlighting the need for adequate prescription and follow-up.Entities:
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Year: 2011 PMID: 21963373 DOI: 10.1016/j.arcped.2011.08.011
Source DB: PubMed Journal: Arch Pediatr ISSN: 0929-693X Impact factor: 1.180