Pierrick J Arnal1,2,3, Fabien Sauvet1,3, Damien Leger3,4, Pascal van Beers1,3, Virginie Bayon3,4, Clément Bougard1,3, Arnaud Rabat1,3, Guillaume Y Millet2,5, Mounir Chennaoui1,3. 1. Institut de Recherche Biomédicale des Armées (IRBA), Unité Fatigue et Vigilance, Brétigny sur Orge, France. 2. Laboratoire de Physiologie de l'Exercice, Université de Lyon, 42000 Saint Etienne, France. 3. Université Paris Descartes, Sorbonne Paris Cité, EA7330 VIFASOM (Vigilance Fatigue et Sommeil), Hôtel Dieu, Paris, France. 4. Université Paris Descartes, Sorbonne Paris Cité, APHP, Hôtel Dieu, Centre du Sommeil et de la Vigilance, Paris, France. 5. Human Performance Laboratory, Faculty of Kinesiology, University of Calgary, Calgary, Canada.
Abstract
OBJECTIVES: To investigate the effects of 6 nights of sleep extension on sustained attention and sleep pressure before and during total sleep deprivation and after a subsequent recovery sleep. DESIGN: Subjects participated in two experimental conditions (randomized cross-over design): extended sleep (EXT, 9.8 ± 0.1 h (mean ± SE) time in bed) and habitual sleep (HAB, 8.2 ± 0.1 h time in bed). In each condition, subjects performed two consecutive phases: (1) 6 nights of either EXT or HAB (2) three days in-laboratory: baseline, total sleep deprivation and after 10 h of recovery sleep. SETTING: Residential sleep extension and sleep performance laboratory (continuous polysomnographic recording). PARTICIPANTS: 14 healthy men (age range: 26-37 years). INTERVENTIONS:EXT vs. HAB sleep durations prior to total sleep deprivation. MEASUREMENTS AND RESULTS:Total sleep time and duration of all sleep stages during the 6 nights were significantly higher in EXT than HAB. EXT improved psychomotor vigilance task performance (PVT, both fewer lapses and faster speed) and reduced sleep pressure as evidenced by longer multiple sleep latencies (MSLT) at baseline compared to HAB. EXT limited PVT lapses and the number of involuntary microsleeps during total sleep deprivation. Differences in PVT lapses and speed and MSLT at baseline were maintained after one night of recovery sleep. CONCLUSION: Six nights of extended sleep improve sustained attention and reduce sleep pressure. Sleep extension also protects against psychomotor vigilance task lapses and microsleep degradation during total sleep deprivation. These beneficial effects persist after one night of recovery sleep.
RCT Entities:
OBJECTIVES: To investigate the effects of 6 nights of sleep extension on sustained attention and sleep pressure before and during total sleep deprivation and after a subsequent recovery sleep. DESIGN: Subjects participated in two experimental conditions (randomized cross-over design): extended sleep (EXT, 9.8 ± 0.1 h (mean ± SE) time in bed) and habitual sleep (HAB, 8.2 ± 0.1 h time in bed). In each condition, subjects performed two consecutive phases: (1) 6 nights of either EXT or HAB (2) three days in-laboratory: baseline, total sleep deprivation and after 10 h of recovery sleep. SETTING: Residential sleep extension and sleep performance laboratory (continuous polysomnographic recording). PARTICIPANTS: 14 healthy men (age range: 26-37 years). INTERVENTIONS: EXT vs. HAB sleep durations prior to total sleep deprivation. MEASUREMENTS AND RESULTS: Total sleep time and duration of all sleep stages during the 6 nights were significantly higher in EXT than HAB. EXT improved psychomotor vigilance task performance (PVT, both fewer lapses and faster speed) and reduced sleep pressure as evidenced by longer multiple sleep latencies (MSLT) at baseline compared to HAB. EXT limited PVT lapses and the number of involuntary microsleeps during total sleep deprivation. Differences in PVT lapses and speed and MSLT at baseline were maintained after one night of recovery sleep. CONCLUSION: Six nights of extended sleep improve sustained attention and reduce sleep pressure. Sleep extension also protects against psychomotor vigilance task lapses and microsleep degradation during total sleep deprivation. These beneficial effects persist after one night of recovery sleep.
Authors: Miroslaw Mackiewicz; Keith R Shockley; Micah A Romer; Raymond J Galante; John E Zimmerman; Nirinjini Naidoo; Donald A Baldwin; Shane T Jensen; Gary A Churchill; Allan I Pack Journal: Physiol Genomics Date: 2007-08-14 Impact factor: 3.107
Authors: M Thomas; H Sing; G Belenky; H Holcomb; H Mayberg; R Dannals; H Wagner; D Thorne; K Popp; L Rowland; A Welsh; S Balwinski; D Redmond Journal: J Sleep Res Date: 2000-12 Impact factor: 3.981