Literature DB >> 31419329

Efficacy of THN102 (a combination of modafinil and flecainide) on vigilance and cognition during 40-hour total sleep deprivation in healthy subjects: Glial connexins as a therapeutic target.

Fabien Sauvet1,2, Mégane Erblang1,2, Danielle Gomez-Merino1,2, Arnaud Rabat1,2, Mathias Guillard1,2, Dominique Dubourdieu3, Hervé Lefloch3, Catherine Drogou1,2, Pascal Van Beers1,2, Clément Bougard1,2, Cyprien Bourrrilhon1, Pierrick Arnal1,2, Werner Rein4, Franck Mouthon4, Francoise Brunner-Ferber5, Damien Leger2,6, Yves Dauvilliers7, Mounir Chennaoui1,2, Mathieu Charvériat4.   

Abstract

Entities:  

Keywords:  executive function; flecainide; modafinil; psychomotor vigilance task; safety; sleep deprivation; sustained attention; working memory

Mesh：

Substances：

Year:  2019        PMID： 31419329      PMCID： PMC6848897          DOI： 10.1111/bcp.14098

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN： 0306-5251            Impact factor:   4.335


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  49 in total

1.  A parametric study of prefrontal cortex involvement in human working memory.

Authors:  T S Braver; J D Cohen; L E Nystrom; J Jonides; E E Smith; D C Noll
Journal:  Neuroimage       Date:  1997-01       Impact factor: 6.556

2.  Effect of one night of sleep loss on changes in tumor necrosis factor alpha (TNF-α) levels in healthy men.

Authors:  M Chennaoui; F Sauvet; C Drogou; P Van Beers; C Langrume; M Guillard; B Gourby; C Bourrilhon; G Florence; D Gomez-Merino
Journal:  Cytokine       Date:  2011-07-06       Impact factor: 3.861

Review 3.  Treatment Options for Narcolepsy.

Authors:  Lucie Barateau; Régis Lopez; Yves Dauvilliers
Journal:  CNS Drugs       Date:  2016-05       Impact factor: 5.749

4.  Maximizing sensitivity of the psychomotor vigilance test (PVT) to sleep loss.

Authors:  Mathias Basner; David F Dinges
Journal:  Sleep       Date:  2011-05-01       Impact factor: 5.849

5.  Performance and alertness effects of caffeine, dextroamphetamine, and modafinil during sleep deprivation.

Authors:  Nancy J Wesensten; William D S Killgore; Thomas J Balkin
Journal:  J Sleep Res       Date:  2005-09       Impact factor: 3.981

6.  Sustaining executive functions during sleep deprivation: A comparison of caffeine, dextroamphetamine, and modafinil.

Authors:  William D S Killgore; Ellen T Kahn-Greene; Nancy L Grugle; Desiree B Killgore; Thomas J Balkin
Journal:  Sleep       Date:  2009-02       Impact factor: 5.849

7.  Evaluation of the safety of modafinil for treatment of excessive sleepiness.

Authors:  Thomas Roth; Jonathan R L Schwartz; Max Hirshkowitz; Milton K Erman; Jeffrey M Dayno; Sanjay Arora
Journal:  J Clin Sleep Med       Date:  2007-10-15       Impact factor: 4.062

8.  Interest of modafinil, a new psychostimulant, during a sixty-hour sleep deprivation experiment.

Authors:  D Lagarde; D Batejat; P Van Beers; D Sarafian; S Pradella
Journal:  Fundam Clin Pharmacol       Date:  1995       Impact factor: 2.748

9.  Executive control of attention in narcolepsy.

Authors:  Sophie Bayard; Muriel Croisier Langenier; Valérie Cochen De Cock; Sabine Scholz; Yves Dauvilliers
Journal:  PLoS One       Date:  2012-04-25       Impact factor: 3.240

10.  Cortico-Amygdala-Striatal Activation by Modafinil/Flecainide Combination.

Authors:  Dominique Vodovar; Adeline Duchêne; Catriona Wimberley; Claire Leroy; Géraldine Pottier; Yves Dauvilliers; Christian Giaume; Jian-Sheng Lin; Franck Mouthon; Nicolas Tournier; Mathieu Charvériat
Journal:  Int J Neuropsychopharmacol       Date:  2018-07-01       Impact factor: 5.176
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  5 in total

1.  Efficacy of THN201, a Combination of Donepezil and Mefloquine, to Reverse Neurocognitive Deficits in Alzheimer's Disease.

Authors:  Marine Droguerre; Adeline Duchêne; Christèle Picoli; Benjamin Portal; Camille Lejards; Bruno P Guiard; Johann Meunier; Vanessa Villard; Nicole Déglon; Michel Hamon; Franck Mouthon; Mathieu Charvériat
Journal:  Front Neurosci       Date:  2020-06-16       Impact factor: 4.677

Review 2.  Modeling and Targeting Neuroglial Interactions with Human Pluripotent Stem Cell Models.

Authors:  Julie Bigarreau; Nathalie Rouach; Anselme L Perrier; Franck Mouthon; Mathieu Charvériat
Journal:  Int J Mol Sci       Date:  2022-01-31       Impact factor: 5.923

Review 3.  Translational approaches to influence sleep and arousal.

Authors:  Ritchie E Brown; Tristan J Spratt; Gary B Kaplan
Journal:  Brain Res Bull       Date:  2022-05-10       Impact factor: 3.715

4.  Action of mefloquine/amitriptyline THN101 combination on neuropathic mechanical hypersensitivity in mice.

Authors:  Baptiste Letellier; Mélanie Kremer; Léa J Becker; Virginie Andry; Yannick Goumon; Quentin Leboulleux; Pierre Hener; Perrine Inquimbert; Nolwenn Couqueberg; Elisabeth Waltisperger; Ipek Yalcin; Franck Mouthon; Marine Droguerre; Mathieu Charvériat; Michel Barrot
Journal:  Pain       Date:  2021-12-01       Impact factor: 6.961

5.  Effects of Caffeine Intake on Cognitive Performance Related to Total Sleep Deprivation and Time on Task: A Randomized Cross-Over Double-Blind Study.

Authors:  Michael Quiquempoix; Fabien Sauvet; Mégane Erblang; Pascal Van Beers; Mathias Guillard; Catherine Drogou; Aurélie Trignol; Anita Vergez; Damien Léger; Mounir Chennaoui; Danielle Gomez-Merino; Arnaud Rabat
Journal:  Nat Sci Sleep       Date:  2022-03-16
  5 in total

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