Literature DB >> 26192137

Chromosomes at Work: Organization of Chromosome Territories in the Interphase Nucleus.

Andrew J Fritz1, A Rasim Barutcu2, Lori Martin-Buley1, André J van Wijnen3, Sayyed K Zaidi1, Anthony N Imbalzano2, Jane B Lian1, Janet L Stein1, Gary S Stein1.   

Abstract

The organization of interphase chromosomes in chromosome territories (CTs) was first proposed more than one hundred years ago. The introduction of increasingly sophisticated microscopic and molecular techniques, now provide complementary strategies for studying CTs in greater depth than ever before. Here we provide an overview of these strategies and how they are being used to elucidate CT interactions and the role of these dynamically regulated, nuclear-structure building blocks in directly supporting nuclear function in a physiologically responsive manner.
© 2015 Wiley Periodicals, Inc.

Entities:  

Keywords:  CTs; INTERPHASE; NUCLEUS

Mesh：

Year:  2016        PMID： 26192137      PMCID： PMC4715719          DOI： 10.1002/jcb.25280

Source DB:  PubMed          Journal:  J Cell Biochem        ISSN： 0730-2312            Impact factor:   4.429


  168 in total

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3.  Looping and interaction between hypersensitive sites in the active beta-globin locus.

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4.  Cell type specific chromosome territory organization in the interphase nucleus of normal and cancer cells.

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