| Literature DB >> 18615590 |
Gary S Stein1, Sayyed K Zaidi, Janet L Stein, Jane B Lian, Andre J van Wijnen, Martin Montecino, Daniel W Young, Amjad Javed, Jitesh Pratap, Je-Yong Choi, Syed A Ali, Sandhya Pande, Mohammad Q Hassan.
Abstract
The regulatory machinery that governs genetic and epigenetic control of gene expression is compartmentalized in nuclear microenvironments. Temporal and spatial parameters of regulatory complex organization and assembly are functionally linked to biological control and are compromised with the onset and progression of tumorigenesis providing a novel platform for cancer diagnosis and treatment.Entities:
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Year: 2008 PMID: 18615590 PMCID: PMC2612589 DOI: 10.1002/jcb.21813
Source DB: PubMed Journal: J Cell Biochem ISSN: 0730-2312 Impact factor: 4.429