Literature DB >> 26187181

Late I(Na) in the Heart: Physiology, Pathology, and Pathways.

Jonathan C Makielski1, John W Kyle2.   

Abstract

Entities:  

Keywords:  Editorials; arrhythmias, cardiac; calcium/calmodulin-dependent protein kinase type 2; long QT syndrome

Mesh：

Substances：

Year:  2015        PMID： 26187181      PMCID： PMC4552247          DOI： 10.1161/CIRCULATIONAHA.115.017980

Source DB:  PubMed          Journal:  Circulation        ISSN： 0009-7322            Impact factor:   29.690


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  22 in total

1.  Selective inhibition of the late sodium current has no adverse effect on electrophysiological or contractile function of the normal heart.

Authors:  Sarah Fernandes; Kirsten Hoyer; Gongxin Liu; Wei-Qun Wang; Arvinder K Dhalla; Luiz Belardinelli; Sridharan Rajamani
Journal:  J Cardiovasc Pharmacol       Date:  2014-06       Impact factor: 3.105

2.  Sodium and calcium regulation in cardiac myocytes: from molecules to heart failure and arrhythmia.

Authors:  Donald M Bers; Ye Chen-Izu
Journal:  J Physiol       Date:  2015-03-15       Impact factor: 5.182

3.  Caveolin-3 suppresses late sodium current by inhibiting nNOS-dependent S-nitrosylation of SCN5A.

Authors:  Jianding Cheng; Carmen R Valdivia; Ravi Vaidyanathan; Ravi C Balijepalli; Michael J Ackerman; Jonathan C Makielski
Journal:  J Mol Cell Cardiol       Date:  2013-03-26       Impact factor: 5.000

4.  Voltage-Gated Sodium Channel Phosphorylation at Ser571 Regulates Late Current, Arrhythmia, and Cardiac Function In Vivo.

Authors:  Patric Glynn; Hassan Musa; Xiangqiong Wu; Sathya D Unudurthi; Sean Little; Lan Qian; Patrick J Wright; Przemyslaw B Radwanski; Sandor Gyorke; Peter J Mohler; Thomas J Hund
Journal:  Circulation       Date:  2015-07-17       Impact factor: 29.690

5.  A novel, potent, and selective inhibitor of cardiac late sodium current suppresses experimental arrhythmias.

Authors:  Luiz Belardinelli; Gongxin Liu; Cathy Smith-Maxwell; Wei-Qun Wang; Nesrine El-Bizri; Ryoko Hirakawa; Serge Karpinski; Cindy Hong Li; Lufei Hu; Xiao-Jun Li; William Crumb; Lin Wu; Dmitry Koltun; Jeff Zablocki; Lina Yao; Arvinder K Dhalla; Sridharan Rajamani; John C Shryock
Journal:  J Pharmacol Exp Ther       Date:  2012-09-25       Impact factor: 4.030

Review 6.  Control of cardiac repolarization by phosphoinositide 3-kinase signaling to ion channels.

Authors:  Lisa M Ballou; Richard Z Lin; Ira S Cohen
Journal:  Circ Res       Date:  2015-01-02       Impact factor: 17.367

Review 7.  Cardiac late Na⁺ current: proarrhythmic effects, roles in long QT syndromes, and pathological relationship to CaMKII and oxidative stress.

Authors:  Luiz Belardinelli; Wayne R Giles; Sridharan Rajamani; Hrayr S Karagueuzian; John C Shryock
Journal:  Heart Rhythm       Date:  2014-11-11       Impact factor: 6.343

8.  Ca2+/calmodulin-dependent protein kinase II-based regulation of voltage-gated Na+ channel in cardiac disease.

Authors:  Olha M Koval; Jedidiah S Snyder; Roseanne M Wolf; Ryan E Pavlovicz; Patric Glynn; Jerry Curran; Nicholas D Leymaster; Wen Dun; Patrick J Wright; Natalia Cardona; Lan Qian; Colleen C Mitchell; Penelope A Boyden; Philip F Binkley; Chenglong Li; Mark E Anderson; Peter J Mohler; Thomas J Hund
Journal:  Circulation       Date:  2012-09-24       Impact factor: 29.690

Review 9.  The role of late I Na in development of cardiac arrhythmias.

Authors:  Charles Antzelevitch; Vladislav Nesterenko; John C Shryock; Sridharan Rajamani; Yejia Song; Luiz Belardinelli
Journal:  Handb Exp Pharmacol       Date:  2014

10.  Protein kinase C and Ca(2+) -calmodulin-dependent protein kinase II mediate the enlarged reverse INCX induced by ouabain-increased late sodium current in rabbit ventricular myocytes.

Authors:  Ying Wu; Leilei Wang; Jihua Ma; Yejia Song; Peihua Zhang; Antao Luo; Chen Fu; Zhenzhen Cao; Xiaojing Wang; John C Shryock; Luiz Belardinelli
Journal:  Exp Physiol       Date:  2015-03-10       Impact factor: 2.969
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  3 in total

1.  Contribution of two-pore K+ channels to cardiac ventricular action potential revealed using human iPSC-derived cardiomyocytes.

Authors:  Sam Chai; Xiaoping Wan; Drew M Nassal; Haiyan Liu; Christine S Moravec; Angelina Ramirez-Navarro; Isabelle Deschênes
Journal:  Am J Physiol Heart Circ Physiol       Date:  2017-03-24       Impact factor: 4.733

2.  Cardiac Late Sodium Channel Current Is a Molecular Target for the Sodium/Glucose Cotransporter 2 Inhibitor Empagliflozin.

Authors:  Koenraad Philippaert; Subha Kalyaanamoorthy; Mohammad Fatehi; Wentong Long; Shubham Soni; Nikole J Byrne; Amy Barr; Jyoti Singh; Jordan Wong; Taylor Palechuk; Chloe Schneider; Ahmed M Darwesh; Zaid H Maayah; John M Seubert; Khaled Barakat; Jason R B Dyck; Peter E Light
Journal:  Circulation       Date:  2021-04-09       Impact factor: 29.690

Review 3.  Phosphorylation of cardiac voltage-gated sodium channel: Potential players with multiple dimensions.

Authors:  Shahid M Iqbal; Rosa Lemmens-Gruber
Journal:  Acta Physiol (Oxf)       Date:  2018-12-16       Impact factor: 6.311
  3 in total

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