Literature DB >> 26186761

An Open-Source Toolbox for Surrogate Modeling of Joint Contact Mechanics.

Ilan Eskinazi, Benjamin J Fregly.   

Abstract

GOAL: Incorporation of elastic joint contact models into simulations of human movement could facilitate studying the interactions between muscles, ligaments, and bones. Unfortunately, elastic joint contact models are often too expensive computationally to be used within iterative simulation frameworks. This limitation can be overcome by using fast and accurate surrogate contact models that fit or interpolate input-output data sampled from existing elastic contact models. However, construction of surrogate contact models remains an arduous task. The aim of this paper is to introduce an open-source program called Surrogate Contact Modeling Toolbox (SCMT) that facilitates surrogate contact model creation, evaluation, and use.
METHODS: SCMT interacts with the third-party software FEBio to perform elastic contact analyses of finite-element models and uses MATLAB to train neural networks that fit the input-output contact data. SCMT features sample point generation for multiple domains, automated sampling, sample point filtering, and surrogate model training and testing.
RESULTS: An overview of the software is presented along with two example applications. The first example demonstrates creation of surrogate contact models of artificial tibiofemoral and patellofemoral joints and evaluates their computational speed and accuracy, while the second demonstrates the use of surrogate contact models in a forward dynamic simulation of an open-chain leg extension-flexion motion.
CONCLUSION: SCMT facilitates the creation of computationally fast and accurate surrogate contact models. Additionally, it serves as a bridge between FEBio and OpenSim musculoskeletal modeling software. SIGNIFICANCE: Researchers may now create and deploy surrogate models of elastic joint contact with minimal effort.

Entities:  

Mesh:

Year:  2015        PMID: 26186761      PMCID: PMC4896840          DOI: 10.1109/TBME.2015.2455510

Source DB:  PubMed          Journal:  IEEE Trans Biomed Eng        ISSN: 0018-9294            Impact factor:   4.538


  35 in total

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3.  FEBio: finite elements for biomechanics.

Authors:  Steve A Maas; Benjamin J Ellis; Gerard A Ateshian; Jeffrey A Weiss
Journal:  J Biomech Eng       Date:  2012-01       Impact factor: 2.097

4.  Mathematical models of passive motion at the human ankle joint by equivalent spatial parallel mechanisms.

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5.  Function of posterior cruciate ligament bundles during in vivo knee flexion.

Authors:  Ramprasad Papannagari; Louis E DeFrate; Kyung W Nha; Jeremy M Moses; Mohamed Moussa; Thomas J Gill; Guoan Li
Journal:  Am J Sports Med       Date:  2007-03-21       Impact factor: 6.202

6.  Co-simulation of neuromuscular dynamics and knee mechanics during human walking.

Authors:  Darryl G Thelen; Kwang Won Choi; Anne M Schmitz
Journal:  J Biomech Eng       Date:  2014-02       Impact factor: 2.097

7.  Anatomy of the lateral retinaculum of the knee.

Authors:  A M Merican; A A Amis
Journal:  J Bone Joint Surg Br       Date:  2008-04

8.  Computational modeling of a forward lunge: towards a better understanding of the function of the cruciate ligaments.

Authors:  Tine Alkjaer; Maja R Wieland; Michael S Andersen; Erik B Simonsen; John Rasmussen
Journal:  J Anat       Date:  2012-10-11       Impact factor: 2.610

9.  Tensile properties of the medial patellofemoral ligament: the effect of specimen orientation.

Authors:  Kwang E Kim; Shan-Ling Hsu; Savio L-Y Woo
Journal:  J Biomech       Date:  2013-11-25       Impact factor: 2.712

10.  Patellar tendon orientation and patellar tracking in male and female knees.

Authors:  Kartik M Varadarajan; Thomas J Gill; Andrew A Freiberg; Harry E Rubash; Guoan Li
Journal:  J Orthop Res       Date:  2010-03       Impact factor: 3.494

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  1 in total

Review 1.  Bioinspired Technologies to Connect Musculoskeletal Mechanobiology to the Person for Training and Rehabilitation.

Authors:  Claudio Pizzolato; David G Lloyd; Rod S Barrett; Jill L Cook; Ming H Zheng; Thor F Besier; David J Saxby
Journal:  Front Comput Neurosci       Date:  2017-10-18       Impact factor: 2.380

  1 in total

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